Anti-CDC42BPB/MRCK beta

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
A304-893A-T	10 µl (10 µg)		-		2 - 8 business days*		164.00€
A304-893A	100 µl (100 µg)		-		2 - 8 business days*		588.00€

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Protein function: Serine/threonine-protein kinase which is an important downstream effector of... more

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Product information "Anti-CDC42BPB/MRCK beta"

Protein function: Serine/threonine-protein kinase which is an important downstream effector of CDC42 and plays a role in the regulation of cytoskeleton reorganization and cell migration. Regulates actin cytoskeletal reorganization via phosphorylation of PPP1R12C and MYL9/MLC2 (PubMed:21457715, PubMed:21949762). In concert with MYO18A and LURAP1, is involved in modulating lamellar actomyosin retrograde flow that is crucial to cell protrusion and migration (PubMed:18854160). Phosphorylates PPP1R12A (PubMed:21457715). In concert with FAM89B/LRAP25 mediates the targeting of LIMK1 to the lamellipodium resulting in its activation and subsequent phosphorylation of CFL1 which is important for lamellipodial F- actin regulation. [The UniProt Consortium]

Keywords:	Anti-MRCK beta, EC=2.7.11.1, Anti-CDC42BP-beta, Anti-DMPK-like beta, Anti-CDC42-binding protein kinase beta, Anti-Serine/threonine-protein kinase MRCK beta, Anti-Myotonic dystrophy protein kinase-like beta
Supplier:	Bethyl Laboratories
Supplier-Nr:	A304-893A

Properties

Application:	WB, IP
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human (Expected: mouse, rat)
Immunogen:	synthetic peptide. The epitope recognized by A304-893A-T maps to a region between residue 750 to 800 of human Serine/threonine-protein kinase MRCK beta using the numbering given in entry Q9Y5S2.2 (GeneID 9578).
Format:	Antigen Affinity Purified