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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| ATA-HPA022821.25 | 25 µl | - |
7 - 10 business days* |
335.00€
|
|||
| ATA-HPA022821.100 | 100 µl | - |
7 - 10 business days* |
446.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Serine/threonine-protein kinase which is an important downstream effector of... more
Product information "Anti-CDC42BPB"
Protein function: Serine/threonine-protein kinase which is an important downstream effector of CDC42 and plays a role in the regulation of cytoskeleton reorganization and cell migration. Regulates actin cytoskeletal reorganization via phosphorylation of PPP1R12C and MYL9/MLC2 (PubMed:21457715, PubMed:21949762). In concert with MYO18A and LURAP1, is involved in modulating lamellar actomyosin retrograde flow that is crucial to cell protrusion and migration (PubMed:18854160). Phosphorylates PPP1R12A (PubMed:21457715). In concert with FAM89B/LRAP25 mediates the targeting of LIMK1 to the lamellipodium resulting in its activation and subsequent phosphorylation of CFL1 which is important for lamellipodial F-actin regulation. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 89% and to rat: 91%
| Keywords: | Anti-MRCK beta, EC=2.7.11.1, Anti-CDC42BP-beta, Anti-DMPK-like beta, Anti-CDC42-binding protein kinase beta, Anti-Serine/threonine-protein kinase MRCK beta, Anti-Myotonic dystrophy protein kinase-like beta |
| Supplier: | Atlas Antibodies |
| Supplier-Nr: | HPA022821 |
Properties
| Application: | IHC, WB |
| Antibody Type: | Polyclonal |
| Conjugate: | No |
| Host: | Rabbit |
| Species reactivity: | human, mouse, rat |
| Immunogen: | Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: KSKFSGAVLN VPDTSDNSKK QMLRTRSKRR FVFKVPEEER LQQRREMLRD PELRSKMISN PTNFNHVAHM GPGDGMQVLM DLPLSAVPPS QEERPGPAPT NLARQPPSRN KPYISWPSSG GSEPSVTVPL RSMSDPDQDF DKEPDSDST (ATA-APrEST70503) |
Database Information
| KEGG ID : | K16307 | Matching products |
| UniProt ID : | Q9Y5S2 | Matching products |
| Gene ID : | GeneID 9578 | Matching products |
| Protein Atlas Nr. : | ENSG00000198752 |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +20°C (International: +20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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