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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
This gene encodes a cell surface glycoprotein that represents the founding member of the... more
Product information "Anti-CD66e"
This gene encodes a cell surface glycoprotein that represents the founding member of the carcinoembryonic antigen (CEA) family of proteins. The encoded protein is used as a clinical biomarker for gastrointestinal cancers and may promote tumor development through its role as a cell adhesion molecule. Additionally, the encoded protein may regulate differentiation, apoptosis, and cell polarity. This gene is present in a CEA family gene cluster on chromosome 19. Alternative splicing results in multiple transcript variants. Protein function: Cell surface glycoprotein that plays a role in cell adhesion, intracellular signaling and tumor progression (PubMed:2803308, PubMed:10910050, PubMed:10864933). Mediates homophilic and heterophilic cell adhesion with other carcinoembryonic antigen-related cell adhesion molecules, such as CEACAM6 (PubMed:2803308). Plays a role as an oncogene by promoting tumor progression, induces resistance to anoikis of colorectal carcinoma cells (PubMed:10910050). [The UniProt Consortium]
Keywords: | Anti-CEA, Anti-CD66e, Anti-CEACAM5, Anti-Meconium antigen 100, Anti-Carcinoembryonic antigen, Anti-Carcinoembryonic antigen-related cell adhesion molecule 5, CD66e Polyclonal Antibody |
Supplier: | Elabscience |
Supplier-Nr: | E-AB-60116 |
Properties
Application: | WB |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, mouse |
Immunogen: | Recombinant protein of human CEACAM5 |
Database Information
KEGG ID : | K06499 | Matching products |
UniProt ID : | P06731 | Matching products |
Gene ID | GeneID 1048 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | 4°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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