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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ABE-30-1735-100 | 100 tests | - |
3 - 11 business days* |
713.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
CD2 belongs to T lymphocyte glycoproteins of immunoglobulin superfamily. Its interaction with... more
Product information "Anti-CD2 / LFA-2 Monoclonal Antibody (Clone:LT2)-APC Conjugated"
CD2 belongs to T lymphocyte glycoproteins of immunoglobulin superfamily. Its interaction with CD58 stabilizes adhesion between T cells and antigen presenting or target cells. Relatively low affinity of CD2 to CD58 (as measured in solution) is compensated within the two-dimensional cell-cell interface to provide tight adhesion. Moreover, T cell activation induces increased CD2 expression and its lateral mobility, making easier contact between CD2 and CD58. Subsequently, T cell activation causes fixation of CD58-CD2 at sites of cell-cell contact, thereby strengthening intercellular adhesion. CD2 deficiency reduces intestinal inflammation and helps to control infection. Protein function: CD2 interacts with lymphocyte function-associated antigen CD58 (LFA-3) and CD48/BCM1 to mediate adhesion between T- cells and other cell types. CD2 is implicated in the triggering of T-cells, the cytoplasmic domain is implicated in the signaling function. [The UniProt Consortium]
Keywords: | Anti-CD2, Anti-SRBC, Anti-LFA-2, Anti-LFA-3 receptor, Anti-Rosette receptor, Anti-Erythrocyte receptor, Anti-T-cell surface antigen CD2, Anti-T-cell surface antigen T11/Leu-5, Anti-CD2 / LFA-2 Monoclonal Antibody (Clone:LT2)-APC Conjugated |
Supplier: | Abeomics |
Supplier-Nr: | 30-1735 |
Properties
Application: | FC, IP |
Antibody Type: | Monoclonal |
Clone: | LT2 |
Conjugate: | APC |
Host: | Mouse |
Species reactivity: | human |
Immunogen: | Normal human blood lymphocytes. |
Database Information
KEGG ID : | K06449 | Matching products |
UniProt ID : | P06729 | Matching products |
Gene ID | GeneID 914 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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