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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
AG-20B-0083PF-C100 | 100 µg | - |
3 - 9 business days* |
429.00€
|
|||
AG-20B-0083PF-C500 | 500 µg | - |
3 - 9 business days* |
1,045.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
APRIL is a secreted cytokine, belonging to the TNF superfamily that binds to transmembrane... more
Product information "Anti-April (mouse), mAb (blocking) (Centotto-1) (preservative free)"
APRIL is a secreted cytokine, belonging to the TNF superfamily that binds to transmembrane activator and CAML interactor (TACI), B cell maturation antigen (BCMA) and can interact with carbohydrate side chains of heparan sulfate proteoglycans (HSPG) that may trigger cross-linking. APRIL maintains B cell homeostasis by acting at a later stage, modulating the function and survival of antigen-experienced B cells. APRIL (as well as BAFF) stimulates class-switch recombination (CSR), hence contributes to shaping humoral effector mechanisms. With regards to humoral memory, APRIL is involved in the establishment and survival of the long-lived plasma cell (LLPC) pool in the bone marrow (BM). Recently, APRIL has been shown to confer atheroprotection via binding to heparan sulfate (HS) chains of heparan-sulfate proteoglycan 2 (HSPG2), which limits LDL retention,macrophage accumulation and necrotic core formation. Protein function: Cytokine that binds to TNFRSF13B/TACI and to TNFRSF17/BCMA. Plays a role in the regulation of tumor cell growth. May be involved in monocyte/macrophage-mediated immunological processes. [The UniProt Consortium]
Keywords: | Anti-CD256, Anti-April, Anti-APRIL, Anti-Tnfsf13, Anti-A proliferation-inducing ligand, Anti-Tumor necrosis factor ligand superfamily member 13 |
Supplier: | AdipoGen Life Sciences |
Supplier-Nr: | AG-20B-0083PF |
Properties
Application: | FA (Blocking), IP |
Antibody Type: | Monoclonal |
Clone: | Centotto-1 |
Conjugate: | No |
Host: | Mouse |
Species reactivity: | mouse |
Immunogen: | Recombinant mouse APRIL. |
Format: | Purified |
Database Information
KEGG ID : | K05475 | Matching products |
UniProt ID : | Q9D777 | Matching products |
Gene ID | GeneID 69583 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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