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Sancycline
Artikelnummer: Cay23100-5
Sancycline is a semisynthetic tetracycline antibiotic that is more active than tetracycline (Cay-14328) against 339 strains of anaerobic bacteria (average MIC90s = 1 and 32 µg/ml, respectively). Sancycline is active against tetracycline-resistant E. coli, S. aureus, and E. faecalis strains with MICs ranging from...
| Schlagworte: | 6-Demethyl-6-deoxytetracycline, GS 2147,... |
| Anwendung: | Antibacterial, Tetracycline antibiotic, Protein biosynthesis inhibitor, 30S subunit inhibitor |
| CAS | 808-26-4 |
| MW: | 414.4 D |
ab 43,00 €
Chlortetracycline
Artikelnummer: Cay23302-5
Chlortetracycline is a broad-spectrum antibiotic originally isolated from S. aureofaciens. It inhibits growth of both Gram-positive and Gram-negative bacteria at a range of 0.1-100 µg/ml against A. aerogenes, D. pneumoniae, E. coli, K. pneumoniae, P. morganii, and several species of Haemophilus, Neisseria,...
| Schlagworte: | 7-Chlortetracycline,... |
| Anwendung: | Broad-spectrum antibiotic, Protein biosynthesis inhibitor |
| CAS | 57-62-5 |
| MW: | 478.9 D |
ab 237,00 €
Rolitetracycline
Artikelnummer: Cay23479-5
Rolitetracycline is a tetracycline antibiotic with bacteriostatic activity at low concentrations (7.8 µg/ml) and bactericidal activity at high concentrations (15.6 µg/ml) against E. coli. It has additive and synergistic effects with penicillin and cephalothin, respectively, in vitro against 34 E. coli and S. aureus...
| Schlagworte: | Pyrrolidinylmethyltetracycline, SQ 15,659,... |
| Anwendung: | Antibacterial, Protein biosynthesis inhibitor |
| CAS | 751-97-3 |
| MW: | 527.6 D |
ab 163,00 €
Doxycycline (hyclate)
Artikelnummer: Cay14422-1
Doxycycline is a broad-spectrum tetracycline antibiotic. It inhibits bacterial protein synthesis by binding to ribosomes. Doxycycline also selectively inhibits human matrix metalloproteinase-8 (MMP-8) and MMP-13 over MMP-1 with 50, 60, and 5% inhibition, respectively, when used at a concentration of 30 µM. It can be...
| Schlagworte: | (4S,4aR,5S,5aR,6R,12aS)-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-... |
| Anwendung: | Antibiotic |
| CAS | 24390-14-5 |
| MW: | 1025.9 D |
ab 43,00 €
Anhydrochlortetracycline (hydrochloride)
Artikelnummer: Cay19941-1
Anhydrochlortetracycline is an impurity of the tetracycline antibiotic chlortetracycline formed by acid degradation. It is a poor inhibitor of protein synthesis and has minor antimicrobial activity against various strains of actinomycetes.Formal Name:...
| Schlagworte: | (4S,4aS,12aS)-7-chloro-4-(dimethylamino)-1,4,4a,5,12,12a-hexahydro-3,10,11,12a-tetrahydroxy-6-methyl-1,12-dioxo-2-naphthac... |
| Anwendung: | Chlortetracycline impurity |
| CAS | 65490-24-6 |
| MW: | 497.3 D |
ab 109,00 €
Tetracycline (hydrochloride)
Artikelnummer: Cay14328-10
Tetracycline is a broad-spectrum antibiotic that prevents bacterial growth by inhibiting protein synthesis. It binds to a single site in the 30S ribosomal subunit which prevents attachment of aminoacyl tRNA to the ribosomal acceptor site. It is used in cell biology as a selective agent in cell culture systems....
| Schlagworte: | (4S,4aS,5aS,6S,12aS)-... |
| Anwendung: | Antibiotic |
| CAS | 64-75-5 |
| MW: | 480.9 D |
ab 48,00 €
Minocycline (hydrochloride hydrate)
Artikelnummer: Cay14454-25
Minocycline is a broad-spectrum tetracycline antibiotic. It is active against E. faecium in vitro (MIC = 16 mg/L). Minocycline (20 mg/kg every 12 hours) reduces the number of bacteria in the lung in a mouse model of multidrug resistant A. baumannii-induced pneumonia. It reduces spinal cord lesion size and improves...
| Schlagworte: | NSC 141993,... |
| Anwendung: | Antibiotic |
| MW: | 493.9 D |
ab 43,00 €
Oxytetracycline
Artikelnummer: Cay18076-10
Oxytetracycline is a broad-spectrum tetracycline antibiotic that inhibits protein synthesis in both Gram-positive and Gram-negative bacteria. The features of its biosynthesis often serve as a representative example for understanding the synthesis of other type II polyketides. Oxytetracycline is also used to examine...
| Schlagworte: | NSC 9169, Terramycin,... |
| Anwendung: | Antibiotic, Protein synthesis inhibitor |
| CAS | 79-57-2 |
| MW: | 460.4 D |
ab 43,00 €
Epitetracycline (hydrochloride)
Artikelnummer: Cay19470-10
Epitetracycline is an epimer of the antibiotic tetracycline (Cay-14328). Epimers of tetracycline form without catalysis and are considered degradation products. Epitetracycline has decreased activity as an antibiotic or a Tet repressor effector but may have stronger toxic effects in animals.Formal Name:...
| Schlagworte: | 4-epi-Tetracycline, Quatrimycin,... |
| Anwendung: | Tetracycline degradation product |
| CAS | 23313-80-6 |
| MW: | 480.9 D |
ab 77,00 €
Methacycline (hydrochloride)
Artikelnummer: Cay21338-1
Methacycline is a tetracycline-class antibiotic that is active against a wide range of Gram-positive and Gram-negative organisms. It is readily absorbed from the gastrointestinal tract and reaches a maximum concentration at about the fourth hour, declining to a negligible amount in about 24 hours. It is more active...
| Schlagworte: | 6-methylene Oxytetracycline, Rondomycin,... |
| Anwendung: | Antibiotic, Antibacterial, Protein biosynthesis inhibitor |
| CAS | 3963-95-9 |
| MW: | 478.9 D |
ab 43,00 €
Isochlortetracycline
Artikelnummer: Cay22125-1
Isochlortetracycline is an inactive alkaline degradation product of the broad-spectrum antibiotic chlortetracycline. This molecule appears to be a product of in vivo chlortetracycline metabolism with epimerization rates exceeding >50%, and high levels can be detected in the yolks of eggs from chickens exposed to...
| Schlagworte: | 7-Chloroisotetracycline, Isoaureomycin,... |
| Anwendung: | Chlortetracycline metabolite, Reference standard |
| CAS | 514-53-4 |
| MW: | 478.9 D |
ab 77,00 €
4-epi-Chlortetracycline (hydrochloride)
Artikelnummer: Cay16663-500
Chlortetracycline is an analog of tetracycline (Cay-14328), a broad spectrum antibiotic. In addition to its actions against microorganisms, chlortetracycline suppresses inflammation by inhibiting neutrophil action and other aspects of the innate immune response. 4-epi-Chlortetracycline is an epimer of...
| Schlagworte: | 7-chloro-2-Naphthacenecarboxamide,... |
| Anwendung: | Antibiotic, Innate immune response suppressor |
| CAS | 101342-45-4 |
| MW: | 515.3 D |
ab 125,00 €
Demeclocycline (hydrochloride)
Artikelnummer: Cay21759-500
Demeclocycline is a broad-spectrum tetracycline antibiotic produced by S. aureofaciens. It has antimicrobial activity against ~3,200 pathogenic Gram-positive and Gram-negative bacteria in vitro that is 2-fold greater than that of tetracycline (Cay-14328). The bactericidal action of demeclocycline is comparable to...
| Schlagworte: | Demethylchlortetracycline, Demethyltetracycline,... |
| Anwendung: | Antibiotic |
| CAS | 64-73-3 |
| MW: | 501.3 D |
ab 115,00 €
Epioxytetracycline
Artikelnummer: Cay27987-1
Epioxytetracycline is a degradation product of the antibiotic oxytetracycline (Cay-18076). It has been found in swine manure compost and wastewater and is considered a pollutant.Formal Name:...
| Schlagworte: | 4-epi-Oxytetracycline,... |
| Anwendung: | Oxytetracycline degradation product |
| CAS | 14206-58-7 |
| MW: | 460.4 D |
ab 163,00 €
beta-Apooxytetracycline
Artikelnummer: Cay27099-500
beta-Apooxytetracycline is a potential impurity found in commercial preparations of oxytetracycline. beta-Apooxytetracycline is a degradation product formed from oxytetracycline (Cay-18076) via acid hydrolysis. It has a relative potency of 0.1 compared with oxytetracycline for inhibiting the growth of aerobic sludge...
| Schlagworte: | beta-Apo-Oxytetracycline, beta-Apoterramycin,... |
| Anwendung: | Potential impurity, Degradation product |
| CAS | 18751-99-0 |
| MW: | 442.4 D |
ab 54,00 €
Epianhydrotetracycline (hydrochloride)
Artikelnummer: Cay27954-1
Epianhydrotetracycline (EATC) is a degradation product of the antibiotic tetracycline (Cay-14328). EATC is active against Pseudomonas, Agrobacterium, Moraxella, Bacillus, and E. coli (MIC50s = 0.75-16 mg/L).Formal Name:...
| Schlagworte: | EATC,... |
| Anwendung: | Tetracycline degradation product, Antibiotic |
| CAS | 4465-65-0 |
| MW: | 462.9 D |
ab 43,00 €
Doxycycline-d3 (hyclate)
Artikelnummer: Cay28528-1
Doxycycline-d3 is intended for use as an internal standard for the quantification of doxycycline (Cay-14422) by GC- or LC-MS. Doxycycline is a broad-spectrum tetracycline antibiotic. It inhibits bacterial protein synthesis by binding to ribosomes. Doxycycline also selectively inhibits human matrix...
| Schlagworte: | (4S,4aR,5S,5aR,6R,12aS)-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-(6-methyl-d)-1,11-diox... |
| Anwendung: | GC-MS, LC-MS, Internal standard, Quantification, Antibacterial, Protein biosynthesis inhibitor |
| MW: | 894.9 D |
432,00 €
Sancycline (hydrochloride)
Artikelnummer: Cay28118-50
Sancycline is a semisynthetic tetracycline antibiotic that is more active than tetracycline (Cay-14328) against 339 strains of anaerobic bacteria (average MIC90s = 1 and 32 µg/ml, respectively). Sancycline is active against tetracycline-resistant E. coli, S. aureus, and E. faecalis strains with MICs ranging from...
| Schlagworte: | 6-Demethyl-6-deoxytetracycline, NSC 51812,... |
| Anwendung: | Antibacterial tetracycline antibiotic |
| CAS | 6625-20-3 |
| MW: | 450.9 D |
ab 47,00 €