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SMURF2 Protein, Human, Recombinant (His)
SMURF2 Protein, Human, Recombinant (His)

Artikelnummer: TGM-TMPH-01269-100ug

Description: E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Interacts with SMAD7 to trigger SMAD7-mediated transforming growth factor beta/TGF-beta receptor ubiquitin-dependent...
Schlagworte: SMURF2, HECT-type E3 ubiquitin transferase SMURF2, SMAD-specific E3 ubiquitin-protein ligase 2, E3 ubiquitin-protein...
MW: 90.3 kD
ab 198,00 €
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E3 ubiquitin-protein ligase SMURF2 (SMURF2), human, recombinant
E3 ubiquitin-protein ligase SMURF2 (SMURF2), human,...

Artikelnummer: CSB-YP872532HU.1

Organism: Homo sapiens (Human). Source: Yeast. Expression Region: 1-748aa. Protein Length: Full Length. Tag Info: N-terminal 6xHis-tagged. Target Protein Sequence: MSNPGGRRNG PVKLRLTVLC AKNLVKKDFF RLPDPFAKVV VDGSGQCHST DTVKNTLDPK WNQHYDLYIG KSDSVTISVW NHKKIHKKQG AGFLGCVRLL SNAINRLKDT GYQRLDLCKL GPNDNDTVRG QIVVSLQSRD...
Schlagworte: SMURF2, hSMURF2, E3 ubiquitin-protein ligase SMURF2, SMAD ubiquitination regulatory factor 2, HECT-type E3 ubiquitin...
Anwendung: Activity not tested
Exprimiert in: Yeast
Ursprungsart: human
MW: 88.2 kD
ab 242,00 €
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E3 ubiquitin-protein ligase SMURF2 (SMURF2), human, recombinant
E3 ubiquitin-protein ligase SMURF2 (SMURF2), human,...

Artikelnummer: CSB-EP872532HU.1

Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 1-748aa. Protein Length: Full Length. Tag Info: N-terminal GST-tagged. Target Protein Sequence: MSNPGGRRNG PVKLRLTVLC AKNLVKKDFF RLPDPFAKVV VDGSGQCHST DTVKNTLDPK WNQHYDLYIG KSDSVTISVW NHKKIHKKQG AGFLGCVRLL SNAINRLKDT GYQRLDLCKL GPNDNDTVRG QIVVSLQSRD...
Schlagworte: SMURF2, hSMURF2, E3 ubiquitin-protein ligase SMURF2, SMAD ubiquitination regulatory factor 2, HECT-type E3 ubiquitin...
Anwendung: Activity not tested
Exprimiert in: E.coli
Ursprungsart: human
MW: 113.2 kD
ab 219,00 €
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E3 ubiquitin-protein ligase SMURF2 (SMURF2), human, recombinant
E3 ubiquitin-protein ligase SMURF2 (SMURF2), human,...

Artikelnummer: CSB-EP872532HUa0.1

Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 1-748aa. Protein Length: Full Length. Tag Info: N-terminal 6xHis-tagged. Target Protein Sequence: MSNPGGRRNG PVKLRLTVLC AKNLVKKDFF RLPDPFAKVV VDGSGQCHST DTVKNTLDPK WNQHYDLYIG KSDSVTISVW NHKKIHKKQG AGFLGCVRLL SNAINRLKDT GYQRLDLCKL GPNDNDTVRG...
Schlagworte: SMURF2, hSMURF2, E3 ubiquitin-protein ligase SMURF2, SMAD ubiquitination regulatory factor 2, HECT-type E3 ubiquitin...
Anwendung: Activity not tested
Exprimiert in: E.coli
Ursprungsart: human
MW: 90.3 kD
ab 219,00 €
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Anti-SMURF2
Anti-SMURF2

Artikelnummer: CSB-PA967268.100

Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: SMURF2. Antigen Species: Human
Schlagworte: Anti-SMURF2, Anti-hSMURF2, Anti-E3 ubiquitin-protein ligase SMURF2, Anti-SMAD ubiquitination regulatory factor 2,...
Anwendung: ELISA, IHC
Wirt: Rabbit
Spezies-Reaktivität: human, mouse
ab 167,00 €
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Anti-SOCS1
Anti-SOCS1

Artikelnummer: 600-401-ES0

Anti-SOCS1 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with SOCS1 from other sources has not been determined. Protein function: E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and...
Schlagworte: Anti-SMURF2, Anti-hSMURF2, EC=6.3.2.-, Anti-E3 ubiquitin-protein ligase SMURF2, Anti-SMAD ubiquitination regulatory factor...
Anwendung: ELISA, WB
Wirt: Rabbit
Spezies-Reaktivität: human
834,00 €
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SMURF2 intrachain TR-FRET Assay Kit
SMURF2 intrachain TR-FRET Assay Kit

Artikelnummer: BPS-78304

Covalent conjugation to ubiquitin (Ub) is one of the major post-translational modifications that regulates protein stability, function, and localization. Ubiquitination is the concerted action of three enzymes: a Ub-activating enzyme (E1),  a Ub-conjugating enzyme (E2), and a Ub ligase (E3). The specificity and...
Schlagworte: SMAD specific E3 ubiquitin protein ligase 2, SMURF2, TR-FRET Kit, Homogeneous Kit,
Anwendung: Small molecule screening, drug discovery, HTS, kinetics
Spezies-Reaktivität: human
2.298,00 €
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SMURF2, active human recombinant protein
SMURF2, active human recombinant protein

Artikelnummer: BPS-80403

Human SMURF 2 (GenBank Accession No. NM_022739), amino-acids 130-end, with N-terminal DDDDK tag (FLAG), MW= 72 kDa, expressed in a Baculovirus infected Sf9 cell expression system. Useful in conjunction with E1 and E2 for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
Schlagworte: hSMURF2, E3 ubiquitin-protein ligase SMURF2, SMAD ubiquitination regulatory factor 2, HECT-type E3 ubiquitin transferase...
Anwendung: Enzyme kinetics, inhibitor screening
MW: 72 kD
603,00 €
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Anti-SMURF2
Anti-SMURF2

Artikelnummer: NSJ-R32322

0.5mg/ml if reconstituted with 0.2ml sterile DI water. E3 ubiquitin-protein ligase SMURF2 is an enzyme that in humans is encoded by the SMURF2 gene. The SMURF2 gene is mapped to chromosome 17q22-q23 based on sequence similarity between the SMURF2 sequence and a genomic contig. SMURF2 is a HECT domain E3 ubiquitin...
Schlagworte: Anti-SMURF2, Anti-hSMURF2, EC=6.3.2.-, Anti-E3 ubiquitin-protein ligase SMURF2, Anti-SMAD ubiquitination regulatory factor...
Anwendung: WB
Wirt: Rabbit
Spezies-Reaktivität: human
772,00 €
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Anti-SMURF2
Anti-SMURF2

Artikelnummer: ARG59482.100

Protein function: E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Interacts with SMAD1 and SMAD7 in order to trigger their ubiquitination and proteasome-dependent degradation. In...
Schlagworte: Anti-SMURF2, Anti-hSMURF2, Anti-E3 ubiquitin-protein ligase SMURF2, Anti-SMAD ubiquitination regulatory factor 2,...
Anwendung: WB
Wirt: Rabbit
Spezies-Reaktivität: human, mouse, rat
658,00 €
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Anti-SMURF2
Anti-SMURF2

Artikelnummer: ATA-HPA071508.100

Protein function: E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Interacts with SMAD1 and SMAD7 in order to trigger their ubiquitination and proteasome-dependent degradation. In...
Schlagworte: Anti-SMURF2, Anti-hSMURF2, Anti-E3 ubiquitin-protein ligase SMURF2, Anti-SMAD ubiquitination regulatory factor 2,...
Anwendung: WB, IHC, ICC
Wirt: Rabbit
Spezies-Reaktivität: human
ab 320,00 €
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Anti-SMURF2, clone 1826CT865.51.28
Anti-SMURF2, clone 1826CT865.51.28

Artikelnummer: NSJ-F54130-0.05ML

In 1X PBS, pH 7.4, with 0.09% sodium azide. E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Interacts with SMAD1 and SMAD7 in order to trigger their ubiquitination and...
Schlagworte: Anti-hSMURF2, Anti-E3 ubiquitin-protein ligase SMURF2, Anti-SMAD ubiquitination regulatory factor 2, Anti-HECT-type E3...
Anwendung: WB
Wirt: Mouse
Spezies-Reaktivität: human
ab 350,00 €
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