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CBL-B TR-FRET Assay Kit
Artikelnummer: BPS-79575
Human Casitas B-lineage lymphoma proto-oncogene b (CBL-B) is an E3 ubiquitinprotein ligase that functions as a negative regulator of T-cell activation. It is a promising drug target in cancer immunotherapy. The CBL-B TR-FRET Assay Kit is designed to measure CBL-B auto-ubiquitination activity in a homogeneous 384...
| Schlagworte: | UBE1, UBA1, ubcH5b, UBE2D2, E3 ubiquitin-protein ligase CBL-B, RING finger protein 56, CBL, CBLB, HTRF, cblb, |
| Anwendung: | Drug discovery, HTS |
| Spezies-Reaktivität: | human |
3.138,00 €
CBL-B, His-tag, Biotin-labeled
Artikelnummer: BPS-80412-2
Human Casitas B-lineage lymphoma proto-oncogene b (CBL-B), also known as E3 ubiquitin-protein ligase CBL-B, RING finger protein 56, and SH3- binding protein CBL-B GenBank Accession No. NM_170662, a.a. 39 - 426 with N-terminal His-tag and N-terminal Avi-tag, expressed in an E. coli expression system. This protein was...
| Schlagworte: | CBLB, RNF56, Nbla00127, RING finger protein 56, SH3-binding protein CBL-B, Signal transduction protein CBL-B, E3... |
| Anwendung: | Enzyme kinetics, regulation, dephosphorylation, inhibitor screening |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 48 kD |
ab 466,00 €
Anti-Cbl-b
Artikelnummer: A302-902A
Protein function: E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and transfers it to substrates, generally promoting their degradation by the proteasome. Negatively regulates TCR (T-cell receptor), BCR (B- cell receptor) and FCER1 (high affinity immunoglobulin...
| Schlagworte: | Anti-CBLB, Anti-RNF56, Anti-Nbla00127, Anti-RING finger protein 56, Anti-SH3-binding protein CBL-B, Anti-Signal... |
| Anwendung: | WB, IP, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 164,00 €
-30 %
Rabattaktion
Anti-CBLB
Artikelnummer: ARG57312.100
Protein function: E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and transfers it to substrates, generally promoting their degradation by the proteasome. Negatively regulates TCR (T-cell receptor), BCR (B- cell receptor) and FCER1 (high affinity immunoglobulin...
| Schlagworte: | Anti-CBLB, Anti-RNF56, Anti-Nbla00127, Anti-RING finger protein 56, Anti-SH3-binding protein CBL-B, Anti-Signal... |
| Anwendung: | WB, IHC (paraffin) |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
624,00 €
436,80 €
Anti-Cbl-b
Artikelnummer: A302-903A
Protein function: E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and transfers it to substrates, generally promoting their degradation by the proteasome. Negatively regulates TCR (T-cell receptor), BCR (B- cell receptor) and FCER1 (high affinity immunoglobulin...
| Schlagworte: | Anti-CBLB, Anti-RNF56, Anti-Nbla00127, Anti-RING finger protein 56, Anti-SH3-binding protein CBL-B, Anti-Signal... |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 164,00 €
CBL-B (Y363F), His-tag, Biotin-labeled
Artikelnummer: BPS-80413-1
Human Casitas B-lineage lymphoma proto-oncogene b (CBL-B), also known as E3 ubiquitin-protein ligase CBL-B, RING finger protein 56, and SH3- binding protein CBL-B with Y363F mutation GenBank Accession No. NM_170662, a.a. 39 - 426 with N-terminal His-tag and N-terminal Avi-tag, expressed in an E. coli expression...
| Schlagworte: | CBLB, RNF56, Nbla00127, RING finger protein 56, SH3-binding protein CBL-B, Signal transduction protein CBL-B, E3... |
| Anwendung: | Enzyme kinetics, regulation, dephosphorylation, inhibitor screening |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 48 kD |
ab 437,00 €
CBL-B, His-Avi-Tag
Artikelnummer: BPS-80414
Human Casitas B-lineage lymphoma proto-oncogene b (CBL-B), also known as E3 ubiquitin-protein ligase CBL-B, RING finger protein 56, and SH3-binding protein CBL-B, GenBank Accession No. NM_170662, a.a. 39 - 426 with N-terminal His-tag and N-terminal Avi-tag, expressed in an E. coli expression system. MW=48 kDa.
| Schlagworte: | CBLB, RNF56, Nbla00127, RING finger protein 56, SH3-binding protein CBL-B, Signal transduction protein CBL-B, E3... |
| Anwendung: | Enzyme kinetics, regulation, target substrate dephosphorylation, inhibitor screening |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 48 kD |
496,00 €
CBL-B, GST-Tag (Human)
Artikelnummer: BPS-80415
Human Casitas B-lineage lymphoma proto-oncogene b (CBL-B), also known as E3 ubiquitin-protein ligase CBL-B, RING finger protein 56, and SH3-binding protein CBL-B, GenBank Accession No. NM_170662, a.a. 39 - 426 with N-terminal GST-Tag expressed in an E. coli expression system. MW=72 kDa.
| Schlagworte: | CBLB, RNF56, Nbla00127, RING finger protein 56, SH3-binding protein CBL-B, Signal transduction protein CBL-B, E3... |
| Anwendung: | Enzyme kinetics, regulation, target substrate dephosphorylation, inhibitor screening |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 72 kD |
533,00 €
Human CBLB ELISA Kit
Artikelnummer: G-HUFI01885.96
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
641,00 €
Anti-CBLB
Artikelnummer: ATA-HPA018327.100
Protein function: E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and transfers it to substrates, generally promoting their degradation by the proteasome. Negatively regulates TCR (T-cell receptor), BCR (B-cell receptor) and FCER1 (high affinity immunoglobulin...
| Schlagworte: | Anti-CBLB, Anti-RNF56, Anti-Nbla00127, Anti-RING finger protein 56, Anti-SH3-binding protein CBL-B, Anti-E3... |
| Anwendung: | IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 300,00 €
Anti-CBLB
Artikelnummer: ATA-HPA019880.100
Protein function: E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and transfers it to substrates, generally promoting their degradation by the proteasome. Negatively regulates TCR (T-cell receptor), BCR (B-cell receptor) and FCER1 (high affinity immunoglobulin...
| Schlagworte: | Anti-CBLB, Anti-RNF56, Anti-Nbla00127, Anti-RING finger protein 56, Anti-SH3-binding protein CBL-B, Anti-E3... |
| Anwendung: | WB, IHC, ICC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 300,00 €
CBL-B-driven Tyro3 Ubiquitination Intrachain TR-FRET...
Artikelnummer: BPS-78388
Covalent conjugation to ubiquitin (Ub) is one of the major post-translational modifications regulating protein stability, function, and localization. Ubiquitination is the concerted action of three enzymes: a Ub-activating enzyme (E1), a Ub-conjugating enzyme (E2), and a Ub ligase (E3). The specificity and...
| Schlagworte: | CBLB, RNF56, Nbla00127, RING finger protein 56, SH3-binding protein CBL-B, Signal transduction protein CBL-B, E3... |
| Anwendung: | CBL-B Ub ligase inhibitor screening, drug discovery, HTS, IC50 determination, real-time kinetics |
| Spezies-Reaktivität: | human |
3.444,00 €