Zu "K23326" wurden 12 Artikel gefunden!
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NCT02
Artikelnummer: TGM-T60030-2mg
Description: NCT02, a cyclin K degrader, promotes the ubiquitination and proteasomal degradation of cyclin K (CCNK) and its complex partner CDK12, showing promise for metastatic colorectal cancer (CRC) research[1]. Target: Others. Smiles: Cc1cnc(NC(=O)Cc2coc3cc4CCCc4cc23)s1
| Anwendung: | Cyclin K degrader |
| CAS | 790245-61-3 |
| MW: | 312.39 D |
58,00 €
Anti-Cyclin K
Artikelnummer: A301-939A
Protein function: Regulatory subunit of cyclin-dependent kinases that mediates activation of target kinases. Plays a role in transcriptional regulation via its role in regulating the phosphorylation of the C-terminal domain (CTD) of the large subunit of RNA polymerase II (POLR2A). [The UniProt Consortium]
| Schlagworte: | Anti-CCNK, Anti-CPR4, Anti-Cyclin-K |
| Anwendung: | WB, IP, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 178,00 €
NCT-02
Artikelnummer: Cay39568-1
NCT-02 is a degrader of cyclin K. It reduces the levels of cyclin K in patient-derived colorectal cancer (CRC) cells in a concentration-dependent manner. NCT-02 inhibits cancer cell proliferation in CRC tissue samples isolated from the colon (IC50s = 0.9-20.6 µM), as well as from hepatic, lung, and rectal metastases...
| Schlagworte: | 6,7-dihydro-N-(5-methyl-2-thiazolyl)-5H-indeno[5,6-b]furan-3-acetamide |
| Anwendung: | Cyclin K degrader |
| CAS | 790245-61-3 |
| MW: | 312.4 D |
ab 40,00 €
Anti-CCNK
Artikelnummer: ATA-HPA000645.100
Protein function: Regulatory subunit of cyclin-dependent kinases that mediates activation of target kinases. Plays a role in transcriptional regulation via its role in regulating the phosphorylation of the C- terminal domain (CTD) of the large subunit of RNA polymerase II (POLR2A). [The UniProt Consortium] Buffer:...
| Schlagworte: | Anti-CPR4, Anti-CCNK, Anti-Cyclin-K |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 320,00 €
CDK12/Cyclin K, GST-Tags Recombinant
Artikelnummer: BPS-101235
| Schlagworte: | CPR4, CCNK, Cyclin-K, |
| Anwendung: | Enzyme kinetics, inhibitor screening, selectivity profiling |
| Exprimiert in: | insect cells |
| Ursprungsart: | human |
| MW: | 119 + 90 kD |
588,00 €
CDK12 (696-1082)/CyclinK, GST-Tags, Recombinant
Artikelnummer: BPS-100998
Recombinant human Complex of CDK19 and Cyclin. Recombinant human CDK1 (cyclin dependent kinase 12), encompassing amino acids 696-1082. This construct contains an N-terminal GST-tag and includes a Thrombin Cleavage Site to facilitate removal of the GST portion. Recombinant human Cyclin K (CCNK), full length,...
| Schlagworte: | CPR4, CCNK, Cyclin-K, |
| Anwendung: | Enzyme kinetics, inhibitor screening, selectivity profiling |
| Exprimiert in: | insect cells |
| Ursprungsart: | human |
| MW: | 72/90 kD |
588,00 €
CCNK (Vector Vector will be determined during the...
Artikelnummer: CSB-CL004828HU.10
Length: 1065 Sequence: atgaaggaga ataaagaaaa ttcaagccct tcagtaactt cagcaaacct ggaccacaca aagccatgtt ggtactggga taagaaagac ttggctcata caccctcaca acttgaagga cttgatccag ccaccgaggc ccggtaccgc cgagagggcg ctcggttcat ctttgatgtg ggcacacgtt tggggctaca ctatgatacc ctggcaactg gaataattta ttttcatcgc ttctatatgt ttcattcctt...
| Schlagworte: | CPR4, CCNK, Cyclin-K |
| Anwendung: | Molecular biology, clone |
| Spezies-Reaktivität: | human |
176,00 €
CyclinK protein-GST fusion
Artikelnummer: 009-001-R81S
Recombinant full-length human CyclinK was expressed by baculovirus in Sf9 insect cells using an N-Terminal Glutathione-S-Transferase fusion protein. The purity was determined to be >85% by densitometry. Protein function: Regulatory subunit of cyclin-dependent kinases that mediates activation of target kinases. Plays...
| Schlagworte: | CCNK, CPR4, Cyclin-K |
| Anwendung: | WB |
| Exprimiert in: | Human |
482,00 €
Anti-CCNK, NT (CCNK, CPR4, Cyclin-K)
Artikelnummer: 033419.200
The protein encoded by this gene is a member of the transcription cyclin family. These cyclins may regulate transcription through their association with and activation of cyclin-dependent kinases (CDK) that phosphorylate the C-terminal domain (CTD) of the large subunit of RNA polymerase II. This gene product may...
| Schlagworte: | Anti-CCNK, Anti-CPR4, Anti-Cyclin-K |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
745,00 €
CCNK PrEST Antigen
Artikelnummer: ATA-APrEST70529.100
Protein function: Regulatory subunit of cyclin-dependent kinases that mediates activation of target kinases. Plays a role in transcriptional regulation via its role in regulating the phosphorylation of the C- terminal domain (CTD) of the large subunit of RNA polymerase II (POLR2A). [The UniProt Consortium] Buffer:...
| Schlagworte: | CPR4, CCNK, Cyclin-K |
| Anwendung: | Control antigen |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
265,00 €
Anti-CCNK
Artikelnummer: G-CAB10261.20
Protein function: Regulatory subunit of cyclin-dependent kinases that mediates activation of target kinases. Plays a role in transcriptional regulation via its role in regulating the phosphorylation of the C- terminal domain (CTD) of the large subunit of RNA polymerase II (POLR2A). [The UniProt Consortium]
| Schlagworte: | Anti-CCNK, Anti-CPR4, Anti-Cyclin-K |
| Anwendung: | WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
149,00 €
Anti-CCNK
Artikelnummer: ELK-ES10509.100
The protein encoded by this gene is a member of the transcription cyclin family. These cyclins may regulate transcription through their association with and activation of cyclin-dependent kinases (CDK) that phosphorylate the C-terminal domain (CTD) of the large subunit of RNA polymerase II. This gene product may...
| Schlagworte: | Anti-CCNK, Anti-CPR4, Anti-Cyclin-K, CCNK rabbit pAb |
| Anwendung: | WB, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 173,00 €