Zu "K22472" wurden 26 Artikel gefunden!
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Adafosbuvir
Artikelnummer: TGM-T26560-5mg
Description: Adafosbuvir has antiviral activity. Target: Others. Smiles: CC(C)OC(=O)[C@H](C)NP(=O)(OC[C@@]1(F)O[C@@H](n2ccc(=O)[nH]c2=O)[C@](C)(O)[C@@H]1O)Oc1ccccc1
| Anwendung: | Targets Hepatitis C virus RNA-dependent RNA polymerase [EC:2.7.7.48] (NS5B) |
| CAS | 1613589-09-5 |
| MW: | 545.457 D |
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Deleobuvir sodium
Artikelnummer: TGM-T70846-100mg
Description: Deleobuvir sodium is the salt form of Deleobuvir, also known as BI207127, a non-nucleoside hepatitis C virus NS5B polymerase inhibitor for the treatment of hepatitis C. Deleobuvir was tested in combination regimens with pegylated interferon and ribavirin, and in interferon-free regimens with other...
| Anwendung: | Targets Hepatitis C virus RNA-dependent RNA polymerase [EC:2.7.7.48] (NS5B) |
| CAS | 1370023-80-5 |
| MW: | 675.56 D |
ab 2.121,00 €
Beclabuvir HCl
Artikelnummer: TGM-T68235-100mg
Description: Beclabuvir, also known as BMS-791325, is an allosteric inhibitor that binds to thumb site 1 of the hepatitis C virus (HCV) NS5B RNA-dependent RNA polymerase. BMS-791325 inhibits recombinant NS5B proteins from HCV genotypes 1, 3, 4, and 5 at 50% inhibitory concentrations (IC50) below 28 nM. In cell...
| Anwendung: | Targets Hepatitis C virus RNA-dependent RNA polymerase [EC:2.7.7.48] (NS5B) |
| CAS | 958002-36-3 |
| MW: | 696.3 D |
ab 1.971,00 €
cis-Lomibuvir
Artikelnummer: TGM-T73814-10mg
Description: Cis-Lomibuvir (cis-VX-222), a cis-isomer of Lomibuvir, is a selective non-nucleoside inhibitor of the hepatitis C virus (HCV) NS5B polymerase (RdRp), targeting thumb pocket 2 with a dissociation constant (Kd) of 17 nM. It exhibits an EC50 of 5.2 nM against the 1b/Con1 HCV subgenomic replicon,...
| Anwendung: | Antiviral, NS5B polymerase inhibitor |
| CAS | 1026785-59-0 |
| MW: | 445.61 D |
ab 574,00 €
Bemnifosbuvir hemisulfate
Artikelnummer: TGM-T9331-100mg
Description: Bemnifosbuvir hemisulfate (AT-527) is a potent inhibitor of HCV virus replication. Target: SARS-CoV, HCV Protease. Smiles:...
| Schlagworte: | AT-527 |
| Anwendung: | Targets Coronaviridae replicase polyprotein 1ab (pp1ab) |
| CAS | 2241337-84-6 |
| MW: | 1261.15 D |
ab 54,00 €
Bemnifosbuvir
Artikelnummer: TGM-T9341-100mg
Description: Bemnifosbuvir (AT-511), a novel phosphoramidate prodrug of 2'-fluoro-2'-C-methylguanosine-5'-monophosphate, exhibits potent in vitro activity against HCV. Target: Others, SARS-CoV, HCV Protease. Smiles: C[C@]1(F)[C@H](N2C=3C(N=C2)=C(NC)N=C(N)N3)O[C@H](COP(OC4=CC=CC=C4)(N[C@H](C(OC(C)C)=O)C)=O)[C@H]1O....
| Schlagworte: | AT-511 |
| Anwendung: | Targets Coronaviridae replicase polyprotein 1ab (pp1ab) |
| CAS | 1998705-64-8 |
| MW: | 581.53 D |
ab 60,00 €
Nesbuvir
Artikelnummer: TGM-TQ0090-100mg
Description: Nesbuvir is a selective hepatitis C virus (HCV) nonstructural protein 5B (NS5B) RNA-dependent polymerase inhibitor.Nesbuvir has an IC50 of 9 nM against hepatocellular carcinoma cells containing 1b HCV replicons. Target: HCV Protease. Smiles: CNC(=O)c1c(oc2cc(N(CCO)S(C)(=O)=O)c(cc12)C1CC1)-c1ccc(F)cc1....
| Schlagworte: | HCV-796 |
| Anwendung: | Targets Hepatitis C virus RNA-dependent RNA polymerase [EC:2.7.7.48] (NS5B) |
| CAS | 691852-58-1 |
| MW: | 446.49 D |
ab 97,00 €
Sofosbuvir
Artikelnummer: TGM-T6676-100mg
Description: Sofosbuvir (GS 7977) is a uridine monophosphate analog inhibitor of hepatitis C virus (HCV) polymerase NS5B that is used as an antiviral agent in the treatment of chronic hepatitis C. Target: HCV Protease. Smiles: CC(C)OC(=O)[C@H](C)NP(=O)(OC[C@H]1O[C@@H](n2ccc(=O)[nH]c2=O)[C@](C)(F)[C@@H]1O)Oc1ccccc1....
| Schlagworte: | PSI-7977, GS 7977 |
| Anwendung: | Targets Hepatitis C virus RNA-dependent RNA polymerase [EC:2.7.7.48] (NS5B) |
| CAS | 1190307-88-0 |
| MW: | 529.45 D |
ab 45,00 €
Lomibuvir
Artikelnummer: TGM-T6729-100mg
Description: Lomibuvir (VCH-222) is a selective, non-nucleoside allosteric inhibitor of HCV NS5B polymerase (RdRp) with a Kd of 17 nM. Lomibuvir inhibits the 1b/Con1 HCV subgenomic replicon with an EC 50 of 5.2 nM. Lomibuvir preferentially inhibits elongative RNA synthesis rather than de novo -initiated RNA...
| Schlagworte: | VCH-222, VX-222 |
| Anwendung: | Targets Hepatitis C virus RNA-dependent RNA polymerase [EC:2.7.7.48] (NS5B) |
| CAS | 1026785-55-6 |
| MW: | 445.61 D |
ab 42,00 €
Tegobuvir
Artikelnummer: TGM-T17029-100mg
Description: Tegobuvir (GS 333126) is a specific and covalent HCV NS5B polymerase inhibitor. Target: HCV Protease. Smiles: Fc1ccccc1-c1nc2ccn(Cc3ccc(nn3)-c3ccc(cc3C(F)(F)F)C(F)(F)F)cc2n1
| Schlagworte: | GS-9190, GS 333126 |
| Anwendung: | Targets Hepatitis C virus RNA-dependent RNA polymerase [EC:2.7.7.48] (NS5B) |
| CAS | 1000787-75-6 |
| MW: | 517.4 D |
ab 81,00 €
Taribavirin hydrochloride
Artikelnummer: TGM-T16992-100mg
Description: Taribavirin hydrochloride is an orally active inosine monophosphate dehydrogenase inhibitor designed to concentrate within the liver to target HCV-infected hepatocytes, while minimizing distribution within red blood cells and the development of hemolytic anemia [2]. Target: Others. Smiles:...
| Anwendung: | Targets Hepatitis C virus RNA-dependent RNA polymerase [EC:2.7.7.48] (NS5B) |
| CAS | 40372-00-7 |
| MW: | 279.68 D |
ab 764,00 €
Balapiravir
Artikelnummer: TGM-T14493-2mg
Description: Balapiravir (R1626, Ro 4588161) is the prodrug of a nucleoside analogue inhibitor of the hepatitis C virus (HCV) RNA-dependent RNA polymerase (R1479, RG1479). IC50 Value: Target: HCV Balapiravir was discontinued for safety reasons in 28-36% of patients (most often for lymphopenia) and the percentage of...
| Schlagworte: | Ro 4588161, R1626 |
| Anwendung: | Targets Hepatitis C virus RNA-dependent RNA polymerase [EC:2.7.7.48] (NS5B) |
| CAS | 690270-29-2 |
| MW: | 494.5 D |
112,00 €