Zu "K22182" wurden 72 Artikel gefunden!
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TXNRD2 Protein, Human, Recombinant (His & SUMO)
Artikelnummer: TGM-TMPH-02198-100ug
Description: Involved in the control of reactive oxygen species levels and the regulation of mitochondrial redox homeostasis. Maintains thioredoxin in a reduced state. May play a role in redox-regulated cell signaling.
| Schlagworte: | TR-beta, TXNRD2, Thioredoxin reductase TR3, Selenoprotein Z, Thioredoxin reductase 2, mitochondrial |
| MW: | 68.9 kD |
ab 193,00 €
TRXR1/TXNRD1 Protein, Human, Recombinant (aa 161-647, His)
Artikelnummer: TGM-TMPY-02271-100ug
Description: Thioredoxin reductase 1 (TXNRD1) which is a selenocysteine-containing protein is overexpressed in many malignancies. TXNRD1 plays a key role in regulating cell growth and transformation, and protects cells against oxidative damage. We investigated the association between TXNRD1 polymorphisms and ATDH...
| Schlagworte: | TXNR, TR1, thioredoxin reductase 1, TR, GRIM-12, TRXR1 |
| MW: | 55 kD |
587,00 €
TrxR inhibitor D9
Artikelnummer: TGM-T29018-100mg
Description: TrxR-IN-D9 is a novel inhibitor of thioredoxin reductase (TrxR). Target: Others. Smiles: [P]([Au+][C-]#CC1=CC=C(OC)C=C1)(C2=CC=CS2)(C3=CC=CC=C3)C4=CC=CC=C4
| Schlagworte: | TrxR-IN-D9, D9 |
| Anwendung: | Thioredoxin reductase (TXNRD) inhibitor |
| CAS | 1527513-89-8 |
| MW: | 596.43 D |
ab 1.491,00 €
LCS3
Artikelnummer: TGM-T60446-100mg
Description: LCS3 is a reversible and non-competitive synergistic inhibitor of glutathione disulfide reductase (GSR) and thioredoxin reductase 1 (TXNRD1) with IC50s of 3.3 µM and 3.8 µM, respectively. LCS3 has antitumour activity, induces apoptosis and can be used in the study of lung adenocarcinoma (LUAD). Target:...
| Anwendung: | GR / TrxR inhibitor |
| CAS | 109844-92-0 |
| MW: | 266.64 D |
ab 51,00 €
TRi-1
Artikelnummer: TGM-T5481-100mg
Description: TRi-1 is irreversible inhibitor of cytosolic thioredoxin reductase 1 (TXNRD1), with an IC50 of 12 nM. TRi-1 has little mitochondrial toxicity for anticancer therapy. Target: Others. Smiles: COc1ccc(c(n1)S(=O)(=O)c1ccc(Cl)cc1)[N+]([O-])=O. References: Stafford WC, et al. Irreversible inhibition of...
| Anwendung: | Irreversible TrxR1 inhibitor |
| CAS | 246020-68-8 |
| MW: | 328.73 D |
ab 66,00 €
Anti-TXNRD2
Artikelnummer: CSB-PA004337.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-SelZ, Anti-TXNRD2, Anti-TR-beta, Anti-KIAA1652, EC=1.8.1.9, Anti-Selenoprotein Z, Anti-Thioredoxin reductase TR3,... |
| Anwendung: | ELISA, WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 106,00 €
Thioredoxin reductase 1, cytoplasmic (TXNRD1),partial,...
Artikelnummer: CSB-EP613705HU.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 1-497aa. Protein Length: Partial of Isoform 5. Tag Info: N-terminal 6xHis-tagged. Target Protein Sequence: MNGPEDLPKS YDYDLIIIGG GSGGLAAAKE AAQYGKKVMV LDFVTPTPLG TRWGLGGTCV NVGCIPKKLM HQAALLGQAL QDSRNYGWKV EETVKHDWDR MIEAVQNHIG SLNWGYRVAL REKKVVYENA...
| Schlagworte: | TR, TXNRD1, GRIM12, GRIM-12, EC=1.8.1.9, Thioredoxin reductase TR1, Thioredoxin reductase 1, cytoplasmic, KM-102-derived... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 58.5 kD |
ab 213,00 €
Thioredoxin reductase 1, mitochondrial (Trxr1), partial,...
Artikelnummer: CSB-EP310089DLU.1
Organism: Drosophila melanogaster (Fruit fly). Source: E.coli. Expression Region: 111-588aa. Protein Length: Partial. Tag Info: C-terminal 6xHis-tagged. Target Protein Sequence: GSYDYDLIVI GGGSAGLACA KEAVLNGARV ACLDFVKPTP TLGTKWGVGG TCVNVGCIPK KLMHQASLLG EAVHEAAAYG WNVDEKIKPD WHKLVQSVQN HIKSVNWVTR VDLRDKKVEY...
| Schlagworte: | EC=1.8.1.9, Thioredoxin reductase 1, mitochondrial, Recombinant Drosophila melanogaster Thioredoxin reductase 1,... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | Drosophila melanogaster |
| MW: | 58.9 kD |
ab 283,00 €
Thioredoxin reductase 2, mitochondrial (TXNRD2), human,...
Artikelnummer: CSB-EP885675HU.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 37-524aa. Protein Length: Full Length of Mature Protein. Tag Info: N-terminal 6xHis-SUMO-tagged. Target Protein Sequence: QRDYDLLVVG GGSGGLACAK EAAQLGRKVA VVDYVEPSPQ GTRWGLGGTC VNVGCIPKKL MHQAALLGGL IQDAPNYGWE VAQPVPHDWR KMAEAVQNHV KSLNWGHRVQ...
| Schlagworte: | SelZ, TXNRD2, TR-beta, KIAA1652, EC=1.8.1.9, Selenoprotein Z, Thioredoxin reductase TR3, Thioredoxin reductase 2,... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 68.9 kD |
ab 213,00 €
LCS3
Artikelnummer: Cay36636-1
LCS3 is an inhibitor of glutathione reductase (GR) and thioredoxin reductase (TrxR, IC50s = 3.3 and 3.8 µM, respectively). It decreases the glutathione (GSH) to oxidized GSH (GSSG) ratio in NCI H1650 and H23 lung adenocarcinoma cells in a concentration-dependent manner. LCS3 (3 µM) induces apoptosis in NCI H1650 and...
| Schlagworte: | N-(4-chlorophenyl)-5-nitro-2-furancarboxamide |
| Anwendung: | GR / TrxR inhibitor |
| CAS | 109844-92-0 |
| MW: | 266.6 D |
ab 44,00 €
Thioredoxin Reductase 1 (human, recombinant)
Artikelnummer: Cay39624-200
Thioredoxin reductase 1 (TrxR1) is an oxidoreductase encoded by the TXNRD1 gene in humans and a member of the antioxidant thioredoxin system, which is involved in the maintenance of cellular thiol redox homeostasis. It exists as a homodimer and contains a dimer interface domain, FAD- and NADPH-binding domains, an...
| Schlagworte: | NADPH-dependent Thioredoxin Reductase, TrxR1, TR, TXNRD1, GRIM12, GRIM-12, EC=1.8.1.9, Thioredoxin reductase TR1,... |
| Anwendung: | WB, SDS-PAGE |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | ~55 kD |
797,00 €
-30 %
Rabattaktion
Anti-TXNRD2, clone 3F2-E12-F10
Artikelnummer: ARG54100.100
Protein function: Maintains thioredoxin in a reduced state. Implicated in the defenses against oxidative stress. May play a role in redox- regulated cell signaling. [The UniProt Consortium]
| Schlagworte: | Anti-SelZ, Anti-TXNRD2, Anti-TR-beta, Anti-KIAA1652, EC=1.8.1.9, Anti-Selenoprotein Z, Anti-Thioredoxin reductase TR3,... |
| Anwendung: | WB |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
624,00 €
436,80 €