Zu "K20796" wurden 21 Artikel gefunden!
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MRK-740
Artikelnummer: Cay26387-1
MRK-740 is an inhibitor of the lysine methyltransferase PR/SET domain 9 (PRDM9, IC50 = 80 nM). It inhibits PRDM9-dependent trimethylation of ectopic histone H3K4 (IC50 = 0.8 µM) and endogenous H3K4 in HEK293 cells in a concentration-dependent manner. MRK-740 induces meiotic defects in mouse spermatocytes.Formal...
| Schlagworte: | 4-[3-(3,5-dimethoxyphenyl)-1,2,4-oxadiazol-5-yl]-1-methyl-9-(2-methyl-4-pyridinyl)-1,4,9-triazaspiro[5.5]undecane |
| Anwendung: | PRDM9 inhibitor |
| CAS | 2387510-80-5 |
| MW: | 464.6 D |
ab 44,00 €
Probable histone-lysine N-methyltransferase PRDM7...
Artikelnummer: CSB-EP873626HU.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 1-492aa. Protein Length: Full Length. Tag Info: N-terminal 6xHis-tagged. Target Protein Sequence: MSPERSQEES PEGDTERTER KPMVKDAFKD ISIYFTKEEW AEMGDWEKTR YRNVKMNYNA LITVGLRATR PAFMCHRRQA IKLQVDDTED SDEEWTPRQQ VKPPWMAFRG EQSKHQKGMP KASFNNESSL...
| Schlagworte: | PFM4, PRDM7, EC=2.1.1.-, PR domain-containing protein 7, PR domain zinc finger protein 7, Probable histone-lysine... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 59.9 kD |
ab 292,00 €
PRDM9, GST-Tag
Artikelnummer: BPS-100078
Human PRDM9, also known as PR domain zinc finger protein 9, MEISETZ, and PR/SET domain 9, GenBank Accession No. NM_020227, a.a. 2-400, with an N-terminal GST-tag, expressed in an E. coli expression system. MW = 73 kDa.
| Schlagworte: | PFM6, PR domain-containing protein 9, PR domain zinc finger protein 9, Protein-lysine N-methyltransferase PRDM9,... |
| Anwendung: | Enzyme kinetics, inhibitor screening, selectivity profiling |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 73 kD |
663,00 €
Anti-Prdm9
Artikelnummer: NSJ-R35239-100UG
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: PR domain containing 9 Protein function: Histone methyltransferase that specifically trimethylates 'Lys-4' of histone H3 during meiotic prophase and is essential for proper meiotic progression....
| Schlagworte: | Anti-Prdm9, EC=2.1.1.43, Anti-PR domain-containing protein 9, Anti-PR domain zinc finger protein 9, Anti-Histone-lysine... |
| Anwendung: | WB, ELISA (peptide) |
| Wirt: | Goat |
| Spezies-Reaktivität: | rat |
790,00 €
PRDM9 Chemiluminescent Assay Kit
Artikelnummer: BPS-79625
The PRDM9 Chemiluminescent Assay Kit is designed to measure PRDM9 activity for screening and profiling applications, using purified PRDM9. The PRDM9 Chemiluminescent Assay Kit comes in a convenient format, with 8-well strips pre-coated with histone H3 peptide substrate, an antibody against methylated lysine on...
| Schlagworte: | PFM6, PR domain-containing protein 9, PR domain zinc finger protein 9, Protein-lysine N-methyltransferase PRDM9,... |
| Anwendung: | Enzyme kinetics, HTS |
| Spezies-Reaktivität: | human |
1.204,00 €
Anti-PRDM7
Artikelnummer: E-AB-62374.120
This gene encodes a member of a family of proteins that may have roles in transcription and other nuclear processes. The encoded protein contains a KRAB (Kruppel-associated box) domain -A box and a SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain and may function as a histone methyltransferase. Protein...
| Schlagworte: | Anti-PFM4, Anti-PRDM7, EC=2.1.1.43, Anti-PR domain-containing protein 7, Anti-PR domain zinc finger protein 7,... |
| Anwendung: | WB, IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 243,00 €
Anti-PRDM9
Artikelnummer: ATA-HPA059555.100
Protein function: Histone methyltransferase that sequentially mono-, di-, and tri-methylates both 'Lys-4' (H3K4) and 'Lys-36' (H3K36) of histone H3 to produce respectively trimethylated 'Lys-4' (H3K4me3) and trimethylated 'Lys-36' (H3K36me3) histone H3 and plays a key role in meiotic prophase by determining hotspot...
| Schlagworte: | Anti-PFM6, Anti-PR domain-containing protein 9, Anti-PR domain zinc finger protein 9, Anti-Histone-lysine... |
| Anwendung: | IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 239,00 €
Anti-PRDM7
Artikelnummer: ATA-HPA059944.100
Protein function: Probable histone methyltransferase. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 29% and to rat: 28%
| Schlagworte: | Anti-PFM4, Anti-PRDM7, EC=2.1.1.-, Anti-PR domain-containing protein 7, Anti-PR domain zinc finger protein 7,... |
| Anwendung: | IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 358,00 €
Anti-PRDM7
Artikelnummer: ARG43931.50
Protein function: Probable histone methyltransferase. [The UniProt Consortium]
| Schlagworte: | Anti-PFM4, Anti-PRDM7, Anti-PR domain-containing protein 7, Anti-PR domain-containing protein 7, Anti-PR domain zinc... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
551,00 €
NEU
Anti-prdm9
Artikelnummer: CSB-PA750787XA01DIL.2
Make to order. Production time: 70-80 business days. Deliverables: 1. 200 µg antigen (used as positive control), 2. 1 ml pre-immune serum (used as negative control) , 3. Rabbit polyclonal antibody, antigen affinity purified. Quality Guarantee: 1. Antibody purity > 90% confirmed by SDS-PAGE, 2. Antibody titer > 1:...
| Schlagworte: | Anti-prdm9, Anti-PR domain-containing protein 9, Anti-PR domain zinc finger protein 9, Anti-Histone-lysine... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | Danio rerio (Zebrafish) (Brachydanio rerio) |
ab 1.529,00 €
NEU
Anti-PRDM7
Artikelnummer: CSB-PA873626ZA01HU.2
Make to order. Production time: 70-80 business days. Deliverables: 1. 200 µg antigen (used as positive control), 2. 1 ml pre-immune serum (used as negative control) , 3. Rabbit polyclonal antibody, antigen affinity purified. Quality Guarantee: 1. Antibody purity > 90% confirmed by SDS-PAGE, 2. Antibody titer > 1:...
| Schlagworte: | Anti-PFM4, Anti-PRDM7, EC=2.1.1.-, Anti-PR domain-containing protein 7, Anti-PR domain zinc finger protein 7,... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | Homo sapiens (Human) |
ab 1.529,00 €
PRDM9 (human), recombinant protein
Artikelnummer: ABS-PP-2813.20
| Schlagworte: | Histone-lysine N-methyltransferase PRDM9, PR domain zinc finger protein 9, PR domain-containing protein 9, Protein-lysine... |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 17.5 kD |
ab 90,00 €