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Zu "K19801" wurden 18 Artikel gefunden!
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Artikelnummer: TGM-T2616-100mg
Description: PIK-93, the first potent synthetic PI4K inhibitor, exhibits an IC50 of 19 nM and also inhibits PI3Kalpha with an IC50 of 39 nM. Target: PI3K, mTOR, ATM/ATR, PI4K, DNA-PK, HSV, Carbonic Anhydrase, Virus Protease. Smiles: CC(=O)Nc1nc(C)c(s1)-c1ccc(Cl)c(c1)S(=O)(=O)NCCO. References: Knight ZA, Cell,...
Schlagworte: | PIK 93 |
Anwendung: | PI4K-beta inhibitor |
CAS | 593960-11-3 |
MW: | 389.88 D |
ab 38,00 €
Artikelnummer: Cay39530-1
PI4KIIIbeta inhibitor 3 is an inhibitor of PI4KIIIbeta (IC50 = 19 nM). It is approximately 100-fold selective for PI4KIIIbeta over PI4KIIalpha, PI4KIIbeta, and PI4KIIIalpha, PI3Kalpha, PI3Kbeta, PI3Kgamma, and PI3Kdelta, and PI3KC3, as well as 100-500-fold selective over PI3KC2alpha, PI3KC2beta, and...
Schlagworte: | 4-[5-amino-2-(3-pyridinyl)thiazolo[5,4-d]pyrimidin-7-yl]-N -(4-methylphenyl)-1-piperazinecarboxamide |
Anwendung: | Phosphatidylinositol 4-kinase beta (PI4KB) inhibitor |
CAS | 1245319-54-3 |
MW: | 446.5 D |
ab 82,00 €
Artikelnummer: TGM-T12467-1mg
Description: PI4KIII beta inhibitor 3 is a novel, highly effective inhibitor of PI4KIIIbeta with an IC50 of 5.7 nM. Target: PI3K. Smiles: Cc1ccc(NC(=O)N2CCN(CC2)c2nc(N)nc3sc(nc23)-c2cccnc2)cc1. References: Jean Herman, et al. Autoimmune and inflammatory disorder therapy. From PCT Int. Appl. (2013), WO 2013034738 A1
Anwendung: | PI4KIII beta inhibitor |
CAS | 1245319-54-3 |
MW: | 446.53 D |
ab 251,00 €
Artikelnummer: Cay10009212-10
PIK-93 is an inhibitor of phosphatidylinositol 4-kinase IIIbeta (PI4KIIIbeta, IC50 = 19 nM). It is selective for PI4KIIIbeta over PI4KIIIalpha and PI4KIIalpha (IC50s = 1,100 and >100,000 nM, respectively). However, it also inhibits the PI3K catalytic subunits (IC50s = 39, 590, 120, and 16 nM for p110alpha, p110beta,...
Schlagworte: | N-[5-[4-chloro-3-[[(2-hydroxyethyl)amino]sulfonyl]phenyl]-4-methyl-2-thiazolyl]-acetamide |
Anwendung: | PI4K-beta inhibitor |
CAS | 593960-11-3 |
MW: | 389.9 D |
ab 44,00 €
Artikelnummer: A303-733A
Protein function: Phosphorylates phosphatidylinositol (PI) in the first committed step in the production of the second messenger inositol- 1,4,5,-trisphosphate (PIP). May regulate Golgi disintegration/reorganization during mitosis, possibly via its phosphorylation. Involved in Golgi-to-plasma membrane trafficking....
Schlagworte: | Anti-NPIK, Anti-PI4KB, Anti-PI4K92, Anti-PIK4CB, Anti-PI4Kbeta, Anti-PI4K-beta, EC=2.7.1.67, Anti-PtdIns 4-kinase beta,... |
Anwendung: | WB, IP |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
ab 178,00 €
Artikelnummer: A303-734A
Protein function: Phosphorylates phosphatidylinositol (PI) in the first committed step in the production of the second messenger inositol- 1,4,5,-trisphosphate (PIP). May regulate Golgi disintegration/reorganization during mitosis, possibly via its phosphorylation. Involved in Golgi-to-plasma membrane trafficking....
Schlagworte: | Anti-NPIK, Anti-PI4KB, Anti-PI4K92, Anti-PIK4CB, Anti-PI4Kbeta, Anti-PI4K-beta, EC=2.7.1.67, Anti-PtdIns 4-kinase beta,... |
Anwendung: | WB, IP |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
ab 178,00 €
Artikelnummer: 600-401-J92
Anti-PI4K beta was affinity purified from monospecific antiserum by immunoaffinity chromatography. A BLAST analysis was used to suggest cross-reactivity with bat, rat, primate, mouse, and human based on 100% sequence homology. Cross-reactivity with PI4K beta from other sources has not been determined....
Schlagworte: | Anti-NPIK, Anti-PI4KB, Anti-PIK4CB, Anti-PI4K92, EC=2.7.1.67, Anti-PI4Kbeta, Anti-PI4K-beta, Anti-PtdIns 4-kinase beta,... |
Anwendung: | ELISA, IHC, WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
719,00 €
Artikelnummer: ATA-HPA006280.100
Protein function: Phosphorylates phosphatidylinositol (PI) in the first committed step in the production of the second messenger inositol- 1,4,5,-trisphosphate (PIP). May regulate Golgi disintegration/reorganization during mitosis, possibly via its phosphorylation. Involved in Golgi-to-plasma membrane trafficking....
Schlagworte: | Anti-NPIK, Anti-PIK4CB, Anti-PI4K92, Anti-PI4KIII, Anti-PI4Kbeta, Anti-PI4K-beta, Anti-PtdIns 4-kinase beta,... |
Anwendung: | IHC, WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
ab 239,00 €
Artikelnummer: ATA-HPA006281.100
Protein function: Phosphorylates phosphatidylinositol (PI) in the first committed step in the production of the second messenger inositol- 1,4,5,-trisphosphate (PIP). May regulate Golgi disintegration/reorganization during mitosis, possibly via its phosphorylation. Involved in Golgi-to-plasma membrane trafficking....
Schlagworte: | Anti-NPIK, Anti-PIK4CB, Anti-PI4K92, Anti-PI4KIII, Anti-PI4Kbeta, Anti-PI4K-beta, Anti-PtdIns 4-kinase beta,... |
Anwendung: | IHC |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
ab 358,00 €
NEU
Artikelnummer: ABS-PP-9011.20
Schlagworte: | Phosphatidylinositol 4-kinase beta, PI4K-beta, PI4Kbeta, PtdIns 4-kinase beta, NPIK, PI4K92, PI4KIII, Recombinant Human... |
Exprimiert in: | E.coli |
Ursprungsart: | human |
MW: | 18 kD |
ab 90,00 €
Artikelnummer: CSB-PA017956GA01HU.100
Host Species: Rabbit. Isotype: IgG. Buffer: PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen Affinity Purified. Target Name: PI4KB. Antigen Species: Human
Schlagworte: | Anti-NPIK, Anti-PI4K92, Anti-PIK4CB, Anti-PI4KIII, Anti-PI4Kbeta, Anti-PI4K-beta, Anti-PtdIns 4-kinase beta,... |
Anwendung: | ELISA, WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse, rat |
552,00 €
Artikelnummer: CSB-CL883360HU.10
Length: 2406 Sequence: atgggagata cagtagtgga gcctgccccc ttgaagccaa cttctgagcc cacttctggc ccaccaggga ataatggggg gtccctgcta agtgtcatca cggagggggt cggggaacta tcagtgattg accctgaggt ggcccagaag gcctgccagg aggtgttgga gaaagtcaag cttttgcatg gaggcgtggc agtctctagc agaggcaccc cactggagtt ggtcaatggg gatggtgtgg acagtgagat...
Schlagworte: | NPIK, PI4K92, PIK4CB, PI4KIII, PI4Kbeta, PI4K-beta, PtdIns 4-kinase beta, Phosphatidylinositol 4-kinase beta |
Anwendung: | Molecular biology, clone |
Spezies-Reaktivität: | human |
482,00 €