Zu "K19415" wurden 18 Artikel gefunden!
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Anti-PHF8
Artikelnummer: A301-772A
Protein function: Histone lysine demethylase with selectivity for the di- and monomethyl states that plays a key role cell cycle progression, rDNA transcription and brain development. Demethylates mono- and dimethylated histone H3 'Lys-9' residue (H3K9Me1 and H3K9Me2), dimethylated H3 'Lys-27' (H3K27Me2) and...
| Schlagworte: | Anti-PHF8, Anti-KIAA1111, EC=1.14.11.27, Anti-PHD finger protein 8, Anti-Histone lysine demethylase PHF8 |
| Anwendung: | WB, IP, IHC, ChIP-Seq |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 178,00 €
Anti-PHF8
Artikelnummer: A301-773A-T
Protein function: Histone lysine demethylase with selectivity for the di- and monomethyl states that plays a key role cell cycle progression, rDNA transcription and brain development. Demethylates mono- and dimethylated histone H3 'Lys-9' residue (H3K9Me1 and H3K9Me2), dimethylated H3 'Lys-27' (H3K27Me2) and...
| Schlagworte: | Anti-PHF8, Anti-KIAA1111, EC=1.14.11.27, Anti-PHD finger protein 8, Anti-Histone lysine demethylase PHF8 |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 178,00 €
Anti-PHF8
Artikelnummer: BPS-25308
PHD finger protein 8 (UniProtKB/Swiss Prot entry Q9UPP1) is a jumonji domain containing protein. Like other members of the jumonji family, PHF8 may therefore play a role in histone demethylation. Mutations in PHF8 lead to Siderius type X linked mental retardation (MRXSSD), a mild to borderline type of mental...
| Schlagworte: | Anti-PHF8, Anti-KIAA1111, Anti-PHD finger protein 8, Anti-Histone lysine demethylase PHF8, Anti-[histone... |
| Anwendung: | ELISA, WB |
| Spezies-Reaktivität: | human |
742,00 €
PHF8 (KDM7B), (2-525), FLAG-tag
Artikelnummer: BPS-50131
Human PHF8 also known as KDM7B (lysine-specific demethylase 7B), JHDM1F, and KIAA1111, GenBank Accession No. NM_001184896, a.a. 2 - 525, with N-terminal FLAG-tag, MW=62 kDa, expressed in a Baculovirus-infected Sf9 cell expression system.
| Schlagworte: | PHF8, KIAA1111, PHD finger protein 8, Histone lysine demethylase PHF8, [histone H3]-dimethyl-L-lysine(9) demethylase PHF8,... |
| Anwendung: | Enzyme kinetics, inhibitor screening, selectivity profiling |
| Exprimiert in: | insect cells |
| Ursprungsart: | human |
| MW: | 62 kD |
700,00 €
PHF8 (KDM7B), Full-length, FLAG-tag
Artikelnummer: BPS-50132
Human PHF8 also known as KDM7B (lysine-specific demethylase 7B), JHDM1F, and KIAA1111, GenBank Accession No. NM_001184896, full-length (a.a. 2-1060(end)), with N-terminal FLAG-tag, MW=120 kDa, expressed in a Baculovirus-infected Sf9 cell expression system.
| Schlagworte: | PHF8, KIAA1111, PHD finger protein 8, Histone lysine demethylase PHF8, [histone H3]-dimethyl-L-lysine(9) demethylase PHF8,... |
| Anwendung: | Enzyme kinetics, inhibitor screening, selectivity profiling |
| Exprimiert in: | insect cells |
| Ursprungsart: | human |
| MW: | 120 kD |
700,00 €
Anti-PHF8
Artikelnummer: 600-401-X40
Anti-PHF8 Antibody was purified by affinity purification. This product reacts with human PHF8. Cross reactivity with PHF8 from species other than human is not known. Protein function: Histone lysine demethylase with selectivity for the di- and monomethyl states that plays a key role cell cycle progression, rDNA...
| Schlagworte: | Anti-PHF8, Anti-KIAA1111, EC=1.14.11.27, Anti-PHD finger protein 8, Anti-Histone lysine demethylase PHF8 |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
675,00 €
Anti-PHF8 (IHC)
Artikelnummer: IHC-00343
Protein function: Histone lysine demethylase with selectivity for the di- and monomethyl states that plays a key role cell cycle progression, rDNA transcription and brain development. Demethylates mono- and dimethylated histone H3 'Lys-9' residue (H3K9Me1 and H3K9Me2), dimethylated H3 'Lys-27' (H3K27Me2) and...
| Schlagworte: | Anti-PHF8, Anti-KIAA1111, EC=1.14.11.27, Anti-PHD finger protein 8, Anti-Histone lysine demethylase PHF8 |
| Anwendung: | IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 178,00 €
Methylstat (hydrate)
Artikelnummer: Cay11091-5
Methylstat is a methyl ester prodrug of a Jumonji C domain-containing histone demethylase (JMJD) inhibitor that has favorable cell permeability. The free acid of methylstat inhibits JMJD2A, JMJD2C, JMJD2E, PHF8, and JMJD3 with IC50 values of approximately 4.3, 3.4, 5.9, 10, and 43 µM, respectively, in an in vitro...
| Schlagworte: | 4-[hydroxy[4-[[[4-[[[(1-naphthalenylamino)carbonyl]oxy]methyl]phenyl]methyl]amino]butyl]amino]-4-oxo-2E-butenoic acid,... |
| Anwendung: | JMJD2A / JMJD2C / JMJD2E / PHF8 / JMJD3 inhibitor prodrug |
| MW: | 505.6 D |
ab 74,00 €
PHF8 (KDM7B) Homogeneous Assay Kit
Artikelnummer: BPS-50515-1
The PHF8 Homogeneous Assay Kit is designed to measure the activity of PHF8 for screening and profiling applications. PHF8, also known as JHDM1F and KDM7B, is a JumonjiC (JmjC) domain-containing histone lysine demethylase that exhibits demethylation activity toward dimethyl-lysine 9 on histone H3. The PHF8...
| Schlagworte: | PHF8, KIAA1111, PHD finger protein 8, Histone lysine demethylase PHF8, [histone H3]-dimethyl-L-lysine(9) demethylase PHF8,... |
| Anwendung: | Enzyme kinetics, HTS |
| Spezies-Reaktivität: | human |
ab 1.336,00 €
Anti-PHF8
Artikelnummer: ATA-HPA038779.100
Protein function: Histone lysine demethylase with selectivity for the di- and monomethyl states that plays a key role cell cycle progression, rDNA transcription and brain development. Demethylates mono- and dimethylated histone H3 'Lys-9' residue (H3K9Me1 and H3K9Me2), dimethylated H3 'Lys-27' (H3K27Me2) and...
| Schlagworte: | Anti-PHF8, Anti-KIAA1111, Anti-PHD finger protein 8, Anti-Histone lysine demethylase PHF8, Anti-[histone... |
| Anwendung: | IHC, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
477,00 €
Anti-PHF8
Artikelnummer: ATA-HPA062015.100
Protein function: Histone lysine demethylase with selectivity for the di- and monomethyl states that plays a key role cell cycle progression, rDNA transcription and brain development. Demethylates mono- and dimethylated histone H3 'Lys-9' residue (H3K9Me1 and H3K9Me2), dimethylated H3 'Lys-27' (H3K27Me2) and...
| Schlagworte: | Anti-PHF8, Anti-KIAA1111, Anti-PHD finger protein 8, Anti-Histone lysine demethylase PHF8, Anti-[histone... |
| Anwendung: | ICC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 239,00 €
Daminozide
Artikelnummer: Cay12033-100
Daminozide is an inhibitor of the 2-oxoglutarate histone lysine demethylases KDM2A, PHF8, and KDM7A (IC50s = 1.5, 0.55, and 2.1 µM, respectively) and a plant growth regulator. It is selective for KDM2A, PHF8, and KDM7A over KDM3-6 (IC50s = >100 µM for all), as well as the additional 2-oxoglutarate oxygenases FIH,...
| Schlagworte: | Aminozide, 1-(2,2-dimethylhydrazide)-butanedioic acid |
| Anwendung: | KDM2A/PHF8/KDM7A inhibitor, plant growth regulator |
| CAS | 1596-84-5 |
| MW: | 160.2 D |
36,00 €