Zu "K19021" wurden 32 Artikel gefunden!
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Anti-PDE3A
Artikelnummer: A302-740A
Protein function: Cyclic nucleotide phosphodiesterase with a dual- specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. [The UniProt Consortium]
| Schlagworte: | Anti-PDE3A, Anti-CGI-PDE A, EC=3.1.4.17, Anti-Cyclic GMP-inhibited phosphodiesterase A, Anti-cGMP-inhibited 3',5'-cyclic... |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 178,00 €
3,4-Dehydro Cilostazol
Artikelnummer: TGM-T38135-1mL
Description: 3,4-Dehydro Cilostazol (OPC-13015), an active metabolite of Cilostazol, is used for pharmacokinetic studies[1]. Target: Others. Smiles: O=c1ccc2cc(OCCCCc3nnnn3C3CCCCC3)ccc2[nH]1. References: T R S Satheeshmanikandan, et al. Liquid Chromatography - Tandem Mass Spectrometry for the Simultaneous...
| Anwendung: | Cilostazol active metabolite |
| CAS | 73963-62-9 |
| MW: | 367.44 D |
ab 60,00 €
Anti-PDE3A
Artikelnummer: A302-741A
Protein function: Cyclic nucleotide phosphodiesterase with a dual- specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. [The UniProt Consortium]
| Schlagworte: | Anti-PDE3A, Anti-CGI-PDE A, EC=3.1.4.17, Anti-Cyclic GMP-inhibited phosphodiesterase A, Anti-cGMP-inhibited 3',5'-cyclic... |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 178,00 €
PDE3B, active human recombinant protein
Artikelnummer: BPS-60031
Active human PDE3B (GenBank Accession No. NM_000922), (amino acids 592-end), with N-terminal GST tag, MW = 86 kDa, expressed in a Baculovirus infected Sf9 cell expression system.
| Schlagworte: | cGI-PDE, CGI-PDE A, cGMP-inhibited cAMP phosphodiesterase, Cyclic GMP-inhibited phosphodiesterase A, cGMP-inhibited... |
| Anwendung: | Enzyme kinetics, inhibitor screening |
| MW: | 86 kD |
685,00 €
PDE3A (His-GST), active human recombinant protein
Artikelnummer: BPS-60032
Human PDE3A (GenBank Accession No. NM_000921), amino acids 669-1141(end), with N-terminal His-GST tag, MW = 82 kDa, expressed in a Baculovirus infected Sf9 cell expression system.
| Schlagworte: | cGI-PDE, CGI-PDE A, cGMP-inhibited cAMP phosphodiesterase, Cyclic GMP-inhibited phosphodiesterase A, cGMP-inhibited... |
| Anwendung: | Enzyme kinetics, inhibitor screening, selectivity profiling |
| Exprimiert in: | Baculovirus |
| Ursprungsart: | human |
| MW: | 82 kD |
685,00 €
Vesnarinone
Artikelnummer: Cay23489-1
Vesnarinone is an inhibitor of phosphodiesterase 3 (PDE3, IC50s = 10.7 and 13.2 µM for PDE3A and PDE3B, respectively). It also inhibits ether-a-go-go-related gene 1 (ERG1) channels (IC50 = 1.1 µM in HEK293T cells expressing human ERG1). Vesnarinone (3-300 µM) increases contractile tension in isolated ventricular...
| Schlagworte: | OPC 8212, 6-[4-(3,4-dimethoxybenzoyl)-1-piperazinyl]-3,4-dihydro-2(1H)-quinolinone |
| Anwendung: | PDE3 inhibitor |
| CAS | 81840-15-5 |
| MW: | 395.5 D |
ab 44,00 €
Carbazeran
Artikelnummer: Cay26092-1
Carbazeran is an inhibitor of phosphodiesterase 2 (PDE2) and PDE3. It inhibits cAMP hydrolysis (IC50 = 4.1 µM in rabbit heart ventricles) selectively over cGMP hydrolysis (IC50 = 171 µM). It induces positive inotropic (EC50 = 100 µM) and negative chronotropic effects in isolated rabbit papillary muscle and right...
| Schlagworte: | N-ethyl-carbamic acid, 1-(6,7-dimethoxy-1-phthalazinyl)-4-piperidinyl ester |
| Anwendung: | PDE2 / PDE3 inhibitor |
| CAS | 70724-25-3 |
| MW: | 360.4 D |
ab 44,00 €
Anti-PDE3A
Artikelnummer: ARG10796.50
Protein function: Cyclic nucleotide phosphodiesterase with a dual- specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. [The UniProt Consortium]
| Schlagworte: | Anti-PDE3A, Anti-CGI-PDE A, EC=3.1.4.17, Anti-Cyclic GMP-inhibited phosphodiesterase A, Anti-cGMP-inhibited 3',5'-cyclic... |
| Anwendung: | IF, ELISA, FRET, ICC, IF, IHC (paraffin), IP, WB, DB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, monkey, mouse, rat, Xenopus |
608,00 €
PDE3A (Mouse), GST-Tag
Artikelnummer: BPS-60036
Mouse PDE3A (GenBank Accession No. NM_018779), amino acids 484-1141 end), with N-terminal GST tag, MW = 100 kDa, expressed in a Baculovirus infected Sf9 cell expression system.
| Schlagworte: | Phosphodiesterase, |
| Anwendung: | Enzyme kinetics, inhibitor screening, selectivity profiling |
| Exprimiert in: | insect cells |
| Ursprungsart: | mouse |
| MW: | 100 kD |
685,00 €
PDE3B Assay Kit
Artikelnummer: BPS-60383
The PDE3B Assay Kit is designed for identification of PDE3B inhibitors using fluorescence polarization. The assay is based on the binding of a fluorescent nucleotide monophosphate generated by PDE3B to the binding agent. The key to the PDE3B Assay Kit is the specific binding agent. Using this kit, only two simple...
| Schlagworte: | PDE3B, phosphodiesterase 3B, |
| Anwendung: | Enzyme kinetics, inhibitor screening, drug discovery, HTS |
| Spezies-Reaktivität: | human |
1.255,00 €
Amrinone
Artikelnummer: Cay23898-1
Amrinone is an inhibitor of phosphodiesterase 3 (PDE3, IC50 = 19.5 µM). It increases developed tension and contractile force in isolated cat papillary muscle. Amrinone (1-10 mg/kg) has positive inotropic effects, increasing the rate and force of heart contraction in anesthetized and unanesthetized dogs.Formal Name:...
| Schlagworte: | WIN 40,680, 5-amino-[3,4'-bipyridin]-6(1H)-one |
| Anwendung: | PDE3 inhibitor |
| CAS | 60719-84-8 |
| MW: | 187.2 D |
ab 61,00 €
Mouse PDE3A1 Assay Kit
Artikelnummer: BPS-79606
Phosphodiesterases (PDEs) play an important role in the dynamic regulation of cAMP and cAMP signaling. Mouse PDE3A, also known as cAMP-inhibited phosphodiesterase, has been implicated in cardiovascular function and fertility. The Mouse PDE3A1 Assay Kit is designed for identification of inhibitors of Mouse PDE3A1...
| Schlagworte: | PDE3A, phosphodiesterase 3A, PDE3, |
| Anwendung: | Enzyme kinetics, drug discovery, HTS |
| Spezies-Reaktivität: | mouse |
670,00 €