Zu "K18964" wurden 34 Artikel gefunden!

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Ropidoxuridine
Ropidoxuridine

Artikelnummer: Cay41220-10

Ropidoxuridine is a radiosensitizer and a prodrug form of the antiviral compound idoxuridine (Cay-20222). It also inhibits viral plaque formation in HeLa cells infected by herpes simplex virus 1 (HSV-1) or HSV-2 when used at a concentration of 100 µM. Ropidoxuridine (1,000 mg/kg per day for six days) enhances...
Schlagworte: 5-Iodo-2-pyrimidinone-2'-deoxyribose, IPdR, 1-(2-deoxy-beta-D-erythro-pentofuranosyl)-5-iodo-2(1H)-pyrimidinone
Anwendung: Idoxuridine prodrug, radiosensitizer
CAS 93265-81-7
MW: 338.1 D
ab 272,00 €
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Cyclopropavir
Cyclopropavir

Artikelnummer: TGM-T15028-100mg

Description: Cyclopropavir (Filociclovir, MBX-400) is a compound of broad-spectrum anti-herpesvirus. It has good antiviral activity against cytomegalovirus (CMV), herpes simplex virus (HHV)-6 and HHV-8 (EC50s: 0.7 µM to 8 µM). Target: Others. Smiles: C(O)C1(CO)/C(=C\N2C3=C(N=C2)C(=O)N=C(N)N3)/C1. References: Kern...
Schlagworte: Filociclovir, ZSM-I-62, MBX-400
Anwendung: Targets Herpesviridae DNA polymerase catalytic subunit [EC:2.7.7.7] (UL30, UL54, BALF5, U38)
CAS 632325-71-4
MW: 263.25 D
ab 1.971,00 €
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Penciclovir
Penciclovir

Artikelnummer: TGM-T1643-100mg

Description: Penciclovir (BRL 39123) is a Herpesvirus Nucleoside Analog DNA Polymerase Inhibitor. In HSV infected cells, penciclovir is phosphorylated by viral thymidine kinase and subsequently converted by cellular kinases into the active metabolite, penciclovir triphosphate, which competitively inhibits viral HSV...
Schlagworte: BRL 39123, VSA 671
Anwendung: Targets Herpesviridae DNA polymerase catalytic subunit [EC:2.7.7.7] (UL30, UL54, BALF5, U38)
CAS 39809-25-1
MW: 253.26 D
ab 30,00 €
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Famciclovir
Famciclovir

Artikelnummer: TGM-T1646-100mg

Description: Famciclovir (BRL 42810) is a Herpes Simplex Virus Nucleoside Analog DNA Polymerase Inhibitor. The mechanism of action of famciclovir is as a DNA Polymerase Inhibitor, and DNA Polymerase Inhibitor. Target: DNA/RNA Synthesis, HSV. Smiles: CC(=O)OCC(CCN1C=NC2=C1N=C(N)N=C2)COC(C)=O. References:...
Schlagworte: BRL 42810
Anwendung: Targets Herpesviridae DNA polymerase catalytic subunit [EC:2.7.7.7] (UL30, UL54, BALF5, U38)
CAS 104227-87-4
MW: 321.33 D
ab 31,00 €
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Acyclovir
Acyclovir

Artikelnummer: TGM-T1454-100mg

Description: Acyclovir (Aciclovir) is a synthetic analog of the purine nucleoside, guanosine, with potent antiviral activity against herpes simplex viruses type 1 and 2, varicella-zoster virus and other viruses of the herpesvirus family. Target: HSV, Antibacterial, Apoptosis, DNA/RNA Synthesis, Antibiotic....
Schlagworte: Acycloguanosine, Aciclovir
Anwendung: Targets Herpesviridae DNA polymerase catalytic subunit [EC:2.7.7.7] (UL30, UL54, BALF5, U38)
CAS 59277-89-3
MW: 225.2 D
ab 40,00 €
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Acyclovir sodium
Acyclovir sodium

Artikelnummer: TGM-T1454L-100mg

Description: Acyclovir sodium is an antimetabolite. Acyclovir sodium inhibits HSV-specified DNA polymerases and prevents further viral DNA synthesis. Target: Others. Smiles: [Na+].Nc1nc([O-])c2ncn(COCCO)c2n1. References: Caviness AC, Demmler GJ, Swint JM, Cantor SB. Cost-effectiveness analysis of herpes simplex...
Schlagworte: Aciclovir sodium
Anwendung: Targets Herpesviridae DNA polymerase catalytic subunit [EC:2.7.7.7] (UL30, UL54, BALF5, U38)
CAS 69657-51-8
MW: 248.19 D
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Vidarabine
Vidarabine

Artikelnummer: TGM-T1506-100mg

Description: Vidarabine (Adenine Arabinoside) is a nucleoside antibiotic isolated from Streptomyces antibioticus. It has some antineoplastic properties and has broad spectrum activity against DNA viruses in cell cultures and significant antiviral activity against infections caused by a variety of viruses such as the...
Schlagworte: Vira-A, Arabinosyladenine, Ara-A, 9-beta-D-Arabinofuranosyladenine, Adenine Arabinoside
Anwendung: Targets Herpesviridae DNA polymerase catalytic subunit [EC:2.7.7.7] (UL30, UL54, BALF5, U38)
CAS 5536-17-4
MW: 267.24 D
ab 40,00 €
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Fiacitabine
Fiacitabine

Artikelnummer: TGM-T15280-100mg

Description: Fiacitabine (NSC-382097) is a selective inhibitor of DNA replication of the herpes simplex virus(HSV) (IC50: 2.5 nM and 12.6 nM for HSV1 and HSV2, respectively). Target: HSV. Smiles: Nc1nc(=O)n(cc1I)[C@@H]1O[C@H](CO)[C@@H](O)[C@@H]1F. References: Allaudeen HS, et al. Selective inhibition of DNA...
Schlagworte: FOAC, FIAC, NSC 382097
Anwendung: Targets Herpesviridae DNA polymerase catalytic subunit [EC:2.7.7.7] (UL30, UL54, BALF5, U38)
CAS 69123-90-6
MW: 371.1 D
ab 161,00 €
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Valganciclovir hydrochloride
Valganciclovir hydrochloride

Artikelnummer: TGM-T1533-100mg

Description: Valganciclovir hydrochloride (Valganciclovir HCl) is a hydrochloride salt form of valganciclovir, a prodrug form of ganciclovir, a nucleoside analog of 2'-deoxyguanosine, with antiviral activity. After phosphorylation, valganciclovir is incorporated into DNA, resulting in inhibition of viral DNA...
Schlagworte: Valcyt, Valcyte, Valganciclovir HCl
Anwendung: Targets Herpesviridae DNA polymerase catalytic subunit [EC:2.7.7.7] (UL30, UL54, BALF5, U38)
CAS 175865-59-5
MW: 390.82 D
ab 31,00 €
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Sorivudine
Sorivudine

Artikelnummer: TGM-T16911-10mg

Description: Sorivudine (BV-araU) has antiviral activity against several viruses including varicella zoster virus, herpes simplex type 1 virus, and Epstein-Barr virus by interfering with viral DNA synthesis. Target: DNA/RNA Synthesis. Smiles: OC[C@H]1O[C@H]([C@@H](O)[C@@H]1O)n1cc(\C=C\Br)c(=O)[nH]c1=O. References:...
Schlagworte: BV-araU
Anwendung: Targets Herpesviridae DNA polymerase catalytic subunit [EC:2.7.7.7] (UL30, UL54, BALF5, U38)
CAS 77181-69-2
MW: 349.13 D
ab 55,00 €
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Valomaciclovir stearate
Valomaciclovir stearate

Artikelnummer: TGM-T29093-100mg

Description: Valomaciclovir stearate is a DNA polymerase inhibitor. Valomaciclovir stearate is an orally available drug with broad-spectrum antiviral activity against a variety of important herpesviruses, including Epstein-Barr virus, or EBV (the first virus to be directly associated with human cancer), varicella...
Schlagworte: EPB-348, ABT-606, MIV-606, A-174606.0, RP-606
Anwendung: Targets Herpesviridae DNA polymerase catalytic subunit [EC:2.7.7.7] (UL30, UL54, BALF5, U38)
CAS 195156-77-5
MW: 618.85 D
ab 1.971,00 €
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Omaciclovir
Omaciclovir

Artikelnummer: TGM-T28234-100mg

Description: Omaciclovir is a DNA-directed DNA polymerase inhibitor. Target: Others. Smiles: Nc1nc2n(C[C@H](CO)CCO)cnc2c(=O)[nH]1. References: Bonnafous P, Agut H. Activity of H2G on human herpesvirus-6B strains either sensitive or resistant to ganciclovir. J Clin Virol. 2010 Jun,48(2):153-4. doi:...
Schlagworte: H2G, ABT091, (-)-2HM-HBG, ABT 091, ABT-091, H 2G
Anwendung: Targets Herpesviridae DNA polymerase catalytic subunit [EC:2.7.7.7] (UL30, UL54, BALF5, U38)
CAS 124265-89-0
MW: 253.26 D
ab 1.270,00 €
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