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Zu "K18669" wurden 54 Artikel gefunden!
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Artikelnummer: TGM-TMPY-04380-50ug
Description: Dual specificity tyrosine-phosphorylation-regulated kinase 3, also known as Regulatory erythroid kinase, REDK and DYRK3, is a nucleus protein which belongs to theprotein kinase superfamily, CMGC Ser/Thr protein kinase family and MNB/DYRK subfamily. DYRKs are an emerging family of dual-specificity...
Schlagworte: | hYAK3-2, dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3, DYRK5, RED, REDK |
MW: | 93.5 kD |
487,00 €
Artikelnummer: TGM-T15422-100mg
Description: GSK-626616 is a potent and orally bioavailable DYRK3 inhibitor (IC50: 0.7 nM). It inhibits other members of the DYRK family with similar potency. GSK-626616 is a potential therapy for the treatment of anemia. Target: DYRK. Smiles: Clc1cccc(Cl)c1NC1=NC(=O)\C(S1)=C\c1ccc2nccnc2c1. References: Connie L....
Anwendung: | DYRK3 inhibitor |
CAS | 1025821-33-3 |
MW: | 401.27 D |
ab 44,00 €
Artikelnummer: CSB-BP852896HU.1
Organism: Homo sapiens (Human). Source: Baculovirus. Expression Region: 1-528aa. Protein Length: Extracellular Domain. Tag Info: N-terminal 6xHis-tagged. Target Protein Sequence: MNDHLHVGSH AHGQIQVQQL FEDNSNKRTV LTTQPNGLTT VGKTGLPVVP ERQLDSIHRR QGSSTSLKSM EGMGKVKATP MTPEQAMKQY MQKLTAFEHH EIFSYPEIYF LGLNAKKRQG...
Schlagworte: | DYRK2, Dual specificity tyrosine-phosphorylation-regulated kinase 2, Recombinant Human Dual specificity... |
Anwendung: | Activity not tested |
Exprimiert in: | Insect cells |
Ursprungsart: | human |
MW: | 61.7 kD |
ab 426,00 €
Artikelnummer: Cay19089-5
LDN-192960 is an inhibitor of haspin protein kinase and dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 (DYRK2) with IC50 values of 10 and 48 nM, respectively. It is selective for haspin and DYRK2 over TRKB, CLK1, DYRK1A, DYRK3, ROS, HIPK1, HIPK2, PIM-1, and PIM-2 kinases (IC50s = 720-91,000...
Schlagworte: | 3-[(2,7-dimethoxy-9-acridinyl)thio]-1-propanamine, dihydrochloride |
Anwendung: | HASPIN / DYRK2 inhibitor |
CAS | 2309172-48-1 |
MW: | 401.4 D |
ab 130,00 €
Artikelnummer: Cay29225-1
Leucettine L41 is an inhibitor of dual-specificity tyrosine phosphorylation-regulated kinase 1A (DYRK1A), DYRK2, CDC-like kinase 1 (CLK1), and CLK3 (IC50s = 0.04, 0.035, 0.015, and 4.5 µM, respectively). It also inhibits GSK3alpha/beta and Pim1 with IC50 values of 0.41 and 4.1 µM, respectively. It inhibits...
Schlagworte: | (5Z)-5-(1,3-benzodioxol-5-ylmethylene)-3,5-dihydro-2-(phenylamino)-4H-imidazol-4-one |
Anwendung: | DYRK1A / DYRK2 / CLK1 / CLK3 inhibitor |
CAS | 1112978-84-3 |
MW: | 307.3 D |
ab 84,00 €
Artikelnummer: BPS-40053
Active human DYRK2 (GenBank Accession No. NM_003583), full length with N-terminal His tag, MW = 63.5 kDa, expressed in Baculovirus infected Sf9 cell expression system.
Schlagworte: | DYRK2, Dual specificity tyrosine-phosphorylation-regulated kinase 2, |
Anwendung: | Enzyme kinetics, inhibitor screening |
MW: | 63.5 kD |
525,00 €
-30 %
Rabattaktion
Artikelnummer: ARG54848.100
Protein function: Serine/threonine-protein kinase involved in the regulation of the mitotic cell cycle, cell proliferation, apoptosis, organization of the cytoskeleton and neurite outgrowth. Functions in part via its role in ubiquitin-dependent proteasomal protein degradation. Functions downstream of ATM and...
Schlagworte: | Anti-DYRK2, EC=2.7.12.1, Anti-Dual specificity tyrosine-phosphorylation-regulated kinase 2 |
Anwendung: | WB |
Wirt: | Mouse |
Spezies-Reaktivität: | human |
624,00 €
436,80 €
-30 %
Rabattaktion
Artikelnummer: ARG54849.100
Protein function: Serine/threonine-protein kinase involved in the regulation of the mitotic cell cycle, cell proliferation, apoptosis, organization of the cytoskeleton and neurite outgrowth. Functions in part via its role in ubiquitin-dependent proteasomal protein degradation. Functions downstream of ATM and...
Schlagworte: | Anti-DYRK2, EC=2.7.12.1, Anti-Dual specificity tyrosine-phosphorylation-regulated kinase 2 |
Anwendung: | IHC (paraffin), WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
624,00 €
436,80 €
Artikelnummer: Cay34621-1
GSK626616 is an inhibitor of dual-specificity tyrosine phosphorylation-regulated kinase 3 (DYRK3, IC50 = 0.7 nM). It enhances erythropoietin-induced erythropoiesis in isolated human bone marrow. GSK626616 increases hemoglobin levels in a mouse model of carboplatin- and radiation-induced anemia.Formal Name:...
Schlagworte: | (5Z)-2-[(2,6-dichlorophenyl)amino]-5-(6-quinoxalinylmethylene)-4(5H)-thiazolone |
Anwendung: | DYRK3 inhibitor |
CAS | 1025821-33-3 |
MW: | 401.3 D |
ab 43,00 €
Artikelnummer: G-PACO26365.50
DYRK3 Antibody is a IgG polyclonal antibody from Assay Genie with reactivity against Human and for use in ELISA, IHC applications. DYRK3 Antibody is a high quality polyclonal antibody for research use only.. Protein function: Dual-specificity protein kinase that promotes disassembly of several types of membraneless...
Schlagworte: | Anti-REDK, Anti-Regulatory erythroid kinase, Anti-Dual specificity tyrosine-phosphorylation-regulated kinase 3 |
Anwendung: | ELISA, IHC |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
363,00 €
Artikelnummer: ATA-HPA028065.100
Protein function: Possible non-essential role in spermiogenesis. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 91% and to rat: 88%
Schlagworte: | Anti-DYRK4, EC=2.7.12.1, Anti-Dual specificity tyrosine-phosphorylation-regulated kinase 4 |
Anwendung: | ICC, IHC, WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
ab 335,00 €
Artikelnummer: ATA-HPA056073.100
Protein function: Possible non-essential role in spermiogenesis. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 44% and to rat: 44%
Schlagworte: | Anti-DYRK4, EC=2.7.12.1, Anti-Dual specificity tyrosine-phosphorylation-regulated kinase 4 |
Anwendung: | ICC, IHC |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
ab 335,00 €