Zu "K18438" wurden 35 Artikel gefunden!
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Anti-PDE10A
Artikelnummer: CSB-PA282556.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-PDE10A, EC=3.1.4.35, EC=3.1.4.17, Anti-cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A, 5''-cyclic... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, rat |
ab 106,00 €
Human PDE10A (Phosphodiesterase 10A) ELISA Kit
Artikelnummer: ELK-ELK4132.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human PDE10A. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human PDE10A....
| Schlagworte: | PDE10A, cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
ab 365,00 €
PDE10A1, active human recombinant protein, N-terminal GST...
Artikelnummer: BPS-60099
Human PDE10A1 (GenBank Accession No. NM_001130690), a.a. 2-789(end) with N-terminal GST-tag, MW=116 kDa, expressed in Sf9 cells via a Baculovirus expression system. One unit is defined as the amount of enzyme that will convert 1 pmole of 3',5'-cAMP to 5'- AMP per min at 37°C. Assay condition: 10 mM Tris-HCl, pH 7.4,...
| Schlagworte: | PDE10A, cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A, |
| Anwendung: | Enzyme kinetics, inhibitor screening, selectivity profiling |
| Exprimiert in: | Baculovirus |
| Ursprungsart: | human |
| MW: | 116 kD |
672,00 €
PDE10A assay kit
Artikelnummer: BPS-60400
The PDE10A Assay Kit is designed for identification of PDE10A inhibitors using fluorescence polarization. The assay is based on the binding of a fluorescent nucleotide monophosphate generated by PDE10A to the binding agent. PDE10A is a dual substrate PDE highly expressed in striatal medium spiny neurons. PDE10A...
| Schlagworte: | inhibitor screening, assay kit, PDE10A, |
| Anwendung: | PDE10A assays, inhibitor screening, FP |
599,00 €
PDE10A2, active human recombinant protein
Artikelnummer: BPS-60100
Active human PDE10A2 (GenBank Accession No. NM_006661), full length with N-terminal GST tag, MW= 116 kDa, expressed in a Baculovirus infected Sf9 cell expression system.
| Schlagworte: | PDE10A, cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A, |
| Anwendung: | Enzyme kinetics, inhibitor screening |
| MW: | 116 kD |
672,00 €
Papaverine
Artikelnummer: Cay10011133-100
Papaverine (Cay-10011133) is an analytical reference standard categorized as a muscle relaxant. Papaverine has been found as an impurity in seized heroin. This product is intended for research and forensic applications.Formal Name: 1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy isoquinoline. CAS Number: 58-74-2....
| Schlagworte: | NSC 136630, 1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy isoquinoline |
| Anwendung: | Analytical reference standard, smooth muscle relaxant, phosphodiesterase inhibitor |
| CAS | 58-74-2 |
| MW: | 339.4 D |
ab 125,00 €
TAK-063
Artikelnummer: Cay22208-5
TAK-063 is a potent inhibitor of phosphodiesterase 10A (PDE10A, IC50 = 0.3 nM). It is >15,000-fold selective for PDE10A over other PDEs and exhibits 14276, Cay-ISO60194) with a minimum effective dose (MED) of 0.3 mg/kg, p.o., in wild-type mice but has no effect in PDE10A knockout mice at doses up to 1 mg/kg. TAK-063...
| Schlagworte: | 1-[2-fluoro-4-(1H-pyrazol-1-yl)phenyl]-5-methoxy-3-(1-phenyl-1H-pyrazol-5-yl)-4(1H)-pyridazinone |
| Anwendung: | PDE10A inhibitor |
| CAS | 1238697-26-1 |
| MW: | 428.4 D |
ab 115,00 €
Papaverine hydrochloride
Artikelnummer: CDX-P0164-G025
White powder. Soluble in DMSO, ethanol or dimethylformamide. Alkaloid antispasmodic drug that most usually treats visceral spasm or vasospasm. It has also been used in the treatment of erectile dysfunction. Smooth muscle relaxant and vasodilator. Phosphodiesterase PDE10A inhibitor. Show to have antiviral and...
| Schlagworte: | 6,7-Dimethoxy-1-veratrylisoquinoline, NSC 35443, NCI-C56359 |
| Anwendung: | Smooth muscle relaxant, Vasodilator, PDE10A inhibitor |
| CAS | 61-25-6 |
| MW: | 375,9 D |
ab 138,00 €
Anti-PDE10A
Artikelnummer: ARG10786.50
Protein function: Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. Can hydrolyze both cAMP and cGMP, but has higher affinity for cAMP and is more efficient with cAMP as substrate. May play a critical role in regulating cAMP and cGMP levels in the striatum, a...
| Schlagworte: | Anti-PDE10A, EC=3.1.4.35, EC=3.1.4.17, Anti-cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A |
| Anwendung: | IF, ELISA, ICC, IF, IHC, IP, WB, DB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, monkey, mouse, rat |
576,00 €
PDE10A, Active Murine Recombinant Protein
Artikelnummer: BPS-60101
Active mouse PDE10A GenBank Accession No. NM_011866), full length with N-terminal GST tag, MW=114.5 kDa, expressed in a Baculovirus infected Sf9 cell expression system.
| Schlagworte: | Pde10a, cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A, |
| Anwendung: | Enzyme kinetics, inhibitor screening |
| MW: | 114.5 kD |
672,00 €
PDE10A Active Rat Recombinant Protein
Artikelnummer: BPS-60102
Active rat PDE10A GenBank Accession No. NM_022236), amino acids 449-end with Nterminal GST tag, MW=66 kDa, expressed in a Baculovirus infected Sf9 cell expression system.
| Schlagworte: | Pde10a, cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A, |
| Anwendung: | Enzyme kinetics, inhibitor screening |
| MW: | 66 kD |
672,00 €
PDE10A1 Assay Kit
Artikelnummer: BPS-60385
The PDE10A1 Assay Kit is designed for identification of PDE10A1 inhibitors using fluorescence polarization. The assay is based on the binding of a fluorescent nucleotide monophosphate generated by PDE10A1 to the binding agent. The key to the PDE10A1 Assay Kit is the specific binding agent. Using this kit, only two...
| Schlagworte: | PDE10A, EC=3.1.4.17, EC=3.1.4.35, cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A |
| Anwendung: | Enzyme kinetics, inhibitor screening, drug discovery, HTS |
| Spezies-Reaktivität: | human |
1.173,00 €