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Zu "K18052" wurden 61 Artikel gefunden!
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Artikelnummer: ABS-ES-501.50
Protein function: Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that mediates non-redundant functions in T-cell receptor (TCR) signaling, including T-cells activation, proliferation, differentiation and survival, by mediating activation of multiple...
Schlagworte: | Anti-PRKCT, Anti-PRKCQ, Anti-nPKC-theta, Anti-Protein kinase C theta type |
Anwendung: | ELISA |
Wirt: | Mouse/Mouse |
Spezies-Reaktivität: | human |
1.080,00 €
Artikelnummer: TGM-T5423-10mg
Description: PKC-theta inhibitor is PKC-thetainhibitor, with an IC50 of 12 nM. Target: PKC. Smiles: NCC1CCC(CNc2nc(NCc3ccccc3OC(F)(F)F)ncc2[N+]([O-])=O)CC1. References: Cywin CL, et al. Discovery of potent and selective PKC-theta inhibitors. Bioorg Med Chem Lett. 2007 Jan 1,17(1):225-30.
Anwendung: | PKC-theta inhibitor |
CAS | 736048-65-0 |
MW: | 454.45 D |
ab 264,00 €
Artikelnummer: TGM-T5817-100mg
Description: PKC-theta inhibitor hcl is a selective PKC-thetainhibitor(IC50:12 nM). Target: PKC. Smiles: Cl.NCC1CCC(CNc2nc(NCc3ccccc3OC(F)(F)F)ncc2[N+]([O-])=O)CC1. References: Cywin C L , Dahmann G , Iii A S P , et al. Discovery of potent and selective PKC-theta inhibitors[J]. Bioorganic & Medicinal Chemistry...
Schlagworte: | PKC-theta inhibitor |
Anwendung: | PKC-theta inhibitor |
CAS | 2253640-49-0 |
MW: | 490.91 D |
ab 84,00 €
Artikelnummer: TGM-T12496-100mg
Description: PKC-theta inhibitor 1 is an inhibitor of PKCtheta (Ki of 6 nM). Target: PKC. Smiles: C(F)(F)(F)C=1C2=C(C=CN=C2NN1)C3=CC(=CC=C3)C4(CN)COC4. References: Collier PN, et al. Discovery of Selective, Orally Bioavailable Pyrazolopyridine Inhibitors of Protein Kinase Ctheta (PKCtheta) That Ameliorate Symptoms...
Anwendung: | PKC-theta inhibitor |
CAS | 1160501-81-4 |
MW: | 348.32 D |
ab 1.820,00 €
Artikelnummer: TGM-T13314-100mg
Description: VTX-27 is a selective inhibitor of protein kinase C theta (PKC theta) (Kis: 0.08 nM and 16 nM for PKC theta and PKC delta). Target: PKC. Smiles: FC1=C(C=2C=3C(NN2)=NC=CC3)N=C(C(Cl)=C1)N4C[C@@]([C@](C(C)C)(C)O)(NCC4)[H]. References: Jimenez JM, et al. Design and optimization of selective protein kinase C...
Anwendung: | PKCtheta inhibitor |
CAS | 1321924-70-2 |
MW: | 418.9 D |
ab 84,00 €
Artikelnummer: CSB-PA030273.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
Schlagworte: | Anti-PRKCQ, Anti-PRKCT, Anti-nPKC-theta, Anti-Protein kinase C theta type, KPCT_HUMAN antibody, MGC126514 antibody,... |
Anwendung: | ELISA, WB, IHC |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse, rat |
ab 126,00 €
Artikelnummer: CSB-PA075054.100
Host Species: Rabbit. Isotype: IgG. Buffer: Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antibodies were produced by immunizing rabbits...
Schlagworte: | Anti-phospho-PRKCQ, Anti-phospho-PRKCT, Anti-phospho-nPKC-theta, Anti-phospho-Protein kinase C theta type, KPCT_HUMAN... |
Anwendung: | ELISA, WB, IHC, IF |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse, rat |
340,00 €
Artikelnummer: CSB-PA160849.100
Host Species: Rabbit. Isotype: IgG. Buffer: Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antibodies were produced by immunizing rabbits...
Schlagworte: | Anti-phospho-PRKCQ, Anti-phospho-PRKCT, Anti-phospho-nPKC-theta, Anti-phospho-Protein kinase C theta type, KPCT_HUMAN... |
Anwendung: | ELISA, WB, IHC |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse, rat |
340,00 €
Artikelnummer: CSB-PA443202.100
Host Species: Rabbit. Isotype: IgG. Buffer: Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antibodies were produced by immunizing rabbits...
Schlagworte: | Anti-PRKCQ, Anti-PRKCT, Anti-nPKC-theta, Anti-Protein kinase C theta type, KPCT_HUMAN antibody, MGC126514 antibody,... |
Anwendung: | ELISA, WB, IHC |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse, rat |
283,00 €
Artikelnummer: CSB-PA593320.100
Host Species: Rabbit. Isotype: IgG. Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by...
Schlagworte: | Anti-PRKCQ, Anti-PRKCT, Anti-nPKC-theta, Anti-Protein kinase C theta type, KPCT_HUMAN antibody, MGC126514 antibody,... |
Anwendung: | ELISA, IHC |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
283,00 €
Artikelnummer: CSB-PA798681.100
Host Species: Rabbit. Isotype: IgG. Buffer: Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antibodies were produced by immunizing rabbits...
Schlagworte: | Anti-PRKCQ, Anti-PRKCT, Anti-nPKC-theta, Anti-Protein kinase C theta type, KPCT_HUMAN antibody, MGC126514 antibody,... |
Anwendung: | ELISA, WB, IHC, IF |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse, rat |
283,00 €
Artikelnummer: Cay16726-1
Sotrastaurin is a protein kinase C (PKC) inhibitor that displays immunosuppressive activity, blocking T cell activation through the disruption of downstream NF-kappaB signaling. In cell-free assays, sotrastaurin was reported to inhibit PKCalpha, betaI, delta, epsilon, eta, and theta with Ki values of 0.95, 0.64,...
Schlagworte: | AEB071, 3-(1H-indol-3-yl)-4-[2-(4-methyl-1-piperazinyl)-4-quinazolinyl]-1H-pyrrole-2,5-dione |
Anwendung: | PKC inhibitor, immunosuppressor |
CAS | 425637-18-9 |
MW: | 438.5 D |
ab 67,00 €