Zu "K17721" wurden 43 Artikel gefunden!
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Clopidogrel Carboxylic Acid (hydrochloride)
Artikelnummer: TGM-T36112-10mg
Description: Clopidogrel is an antithrombic compound whose active metabolite is a selective, irreversible antagonist of the platelet purinergic P2Y12 receptor (IC50 = 100 nM). Clopidogrel inhibits ADP-induced platelet aggregation ex vivo and functions as a prodrug whereupon biotransformation to its active thiol...
| Anwendung: | Clopidogrel metabolite, reference standard |
| CAS | 144750-42-5 |
| MW: | 344.26 D |
ab 112,00 €
(±)-N-3-Benzylnirvanol
Artikelnummer: TGM-T37332-100mg
Description: (±)-N-3-Benzylnirvanol is a racemic mixture of (+)-N-3-Benzylnirvanol and (-)-N-3-Benzylnirvanol. Both enantiomers are selective inhibitors of cytochrome P450, specifically inhibiting CYP2C19. (±)-N-3-Benzylnirvanol also reduces plasma cholesterol levels in mice. Target: P450. Smiles:...
| Anwendung: | CYP2C19 inhibitor |
| CAS | 93879-40-4 |
| MW: | 294.35 D |
ab 52,00 €
5-hydroxy Omeprazole
Artikelnummer: TGM-T37659-1mg
Description: 5-hydroxy Omeprazole is a major metabolite of omeprazole , an inhibitor of the gastric H+/K+-ATPase pump.[1] 5-hydroxy Omeprazole is produced from omeprazole by the action of cytochrome P450 (CYP) isoform 2C19, a monooxygenase. [2][3] CYP2C19 polymorphisms significantly influence the metabolism of...
| Anwendung: | Omeprazole metabolite |
| CAS | 92340-57-3 |
| MW: | 361.42 D |
ab 761,00 €
CYP2C19 Protein, Human, Recombinant (His & Myc)
Artikelnummer: TGM-TMPH-01185-100ug
Description: CYP2C19 Protein, Human, Recombinant (His & Myc) is expressed in E. coli.
| Schlagworte: | Cytochrome P450-11A, CYPIIC17, (S)-limonene 7-monooxygenase, CYPIIC19, CYP2C19, Cytochrome P450-254C, (S)-limonene... |
| MW: | 60.6 kD |
ab 281,00 €
(S)-(+)-N-3-Benzylnirvanol
Artikelnummer: TGM-T67926-100mg
Description: (S)-(+)-N-3-Benzylnirvanol (ZSN-76403) is a cytochrome P450 CYP2C19 inhibitor with an IC50 of 0.179 µM, suitable for studying HIV infection. Target: P450, HIV Protease. Smiles: C(C)[C@@]1(C(=O)N(CC2=CC=CC=C2)C(=O)N1)C3=CC=CC=C3. References: Suzuki H, et al. Active-site characteristics of CYP2C19 and...
| Schlagworte: | ZSN-76403 |
| Anwendung: | CYP2C19 inhibitor |
| CAS | 790676-40-3 |
| MW: | 294.35 D |
ab 145,00 €
Omeprazole metabolite Omeprazole sulfone
Artikelnummer: TGM-T12309-100mg
Description: Omeprazole sulfone is a metabolite of Omeprazole that inhibits the proton pump. Target: Proton pump, Others. Smiles: COc1ccc2[nH]c(nc2c1)S(=O)(=O)Cc1ncc(C)c(OC)c1C
| Schlagworte: | Omeprazole sulfone, Omeprazole sulphone |
| Anwendung: | CYP2C19 inhibitor |
| CAS | 88546-55-8 |
| MW: | 361.42 D |
ab 42,00 €
Cytochrome P450 2C19 (CYP2C19), human, recombinant
Artikelnummer: CSB-EP006417HU.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 26-490aa. Protein Length: Full Length of Mature Protein. Tag Info: N-terminal 10xHis-tagged and C-terminal Myc-tagged. Target Protein Sequence: RGKLPPGPTP LPVIGNILQI DIKDVSKSLT NLSKIYGPVF TLYFGLERMV VLHGYEVVKE ALIDLGEEFS GRGHFPLAER ANRGFGIVFS...
| Schlagworte: | CYP2C19, CYPIIC19, CYPIIC17, Cytochrome P450-11A, Cytochrome P450-254C, Cytochrome P450 2C19, Mephenytoin 4-hydroxylase,... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 60.6 kD |
ab 292,00 €
Anti-CYP2C19
Artikelnummer: CSB-PA001958.50
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-CYP2C19, Anti-CYPIIC17, Anti-CYPIIC19, Anti-Cytochrome P450-11A, Anti-Cytochrome P450-254C, Anti-Cytochrome P450... |
| Anwendung: | ELISA, WB, IHC, IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
126,00 €
5-hydroxy Omeprazole
Artikelnummer: Cay10009028-500
5-hydroxy Omeprazole is a metabolite of the H+/K+-ATPase inhibitor omeprazole (Cay-14880). It is formed from omeprazole by the cytochrome P450 (CYP) isoform CYP2C19.Formal Name: 4-methoxy-6-[[(6-methoxy-1H-benzimidazol-2-yl)sulfinyl]methyl]-5-methyl-3-pyridinemethanol. CAS Number: 92340-57-3. Synonyms: 5-hydroxy...
| Schlagworte: | 4-methoxy-6-[[(6-methoxy-1H-benzimidazol-2-yl)sulfinyl]methyl]-5-methyl-3-pyridinemethanol |
| Anwendung: | Omeprazole metabolite |
| CAS | 92340-57-3 |
| MW: | 361.4 D |
ab 417,00 €
(±)4-Hydroxymephenytoin
Artikelnummer: Cay16124-5
(±)4-Hydroxymephenytoin is a metabolite of (R)-mephenytoin (Cay-25891) and (S)-mephenytoin (Cay-11913). It is formed from (R)- and (S)-mephenytoin by the cytochrome P450 (CYP) isoform CYP2C19 in the liver.Formal Name: 5-ethyl-5-(4-hydroxyphenyl)-3-methyl-2,4-imidazolidinedione. CAS Number: 61837-65-8. Molecular...
| Schlagworte: | 5-ethyl-5-(4-hydroxyphenyl)-3-methyl-2,4-imidazolidinedione |
| Anwendung: | (S)-mephenytoin metabolite |
| CAS | 61837-65-8 |
| MW: | 234.3 D |
ab 145,00 €
Clopidogrel Carboxylic Acid (hydrochloride)
Artikelnummer: Cay17871-500
Clopidogrel carboxylic acid is an inactive metabolite of (±)-clopidogrel (Cay-13657) and (S)-(+)-clopidogrel (Cay-21002). It is formed from (±)-clopidogrel and (S)-(+)-clopidogrel by carboxylesterase 1 (CES1).Formal Name: alphaS-(2-chlorophenyl)-6,7-dihydro-thieno[3,2-c]pyridine-5(4H)-acetic acid, monohydrochloride....
| Schlagworte: | SR26334, alphaS-(2-chlorophenyl)-6,7-dihydro-thieno[3,2-c]pyridine-5(4H)-acetic acid, monohydrochloride |
| Anwendung: | Clopidogrel metabolite, reference standard |
| CAS | 144750-42-5 |
| MW: | 344.3 D |
ab 67,00 €
Voriconazole N-oxide
Artikelnummer: Cay28047-5
Voriconazole N-oxide is a major metabolite of the triazole antifungal voriconazole (Cay-15633). It is formed via oxidation of voriconazole by the cytochrome P450 (CYP) isoforms CYP3A4 and CYP2C19.Formal Name:...
| Schlagworte: | UK 121265,... |
| Anwendung: | Major voriconazole metabolite |
| CAS | 618109-05-0 |
| MW: | 365.3 D |
ab 223,00 €