Zu "K17718" wurden 30 Artikel gefunden!
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N-Desethyl amodiaquine dihydrochloride
Artikelnummer: TGM-T12154L-100mg
Description: N-Desethyl amodiaquine dihydrochloride is an antiparasitic agent and the major biologically active amodiaquine metabolite. Its IC50 values against strains V1/S and 3D7 were 97 nM and 25 nM, respectively. Target: Parasite. Smiles: Cl.Cl.CCNCc1cc(Nc2ccnc3cc(Cl)ccc23)ccc1O. References: Sasi P, et al. In...
| Anwendung: | Primary aminodiaquine metabolite |
| CAS | 79049-30-2 |
| MW: | 400.73 D |
ab 112,00 €
N-desmethyl Rosiglitazone
Artikelnummer: TGM-T35717-5mg
Description: N-desmethyl Rosiglitazone is a major metabolite of rosiglitazone , a potent and selective PPARgamma ligand present in formulations that have been used to treat type 2 diabetes. Rosiglitazone is metabolized by the cytochrome P450 (CYP) isoform CYP2C8 to form N-desmethyl rosiglitazone. Target: Others....
| Anwendung: | Rosiglitazone metabolite |
| CAS | 257892-31-2 |
| MW: | 343.4 D |
968,00 €
Anti-CYP2C8
Artikelnummer: CSB-PA007549.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-CYPIIC8, Anti-Cytochrome P450 2C8, Anti-Cytochrome P450 IIC2, Anti-Cytochrome P450 MP-12, Anti-Cytochrome P450 MP-20,... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 106,00 €
Anti-CYP2C8/CYP2C9/CYP2C18/CYP2C19
Artikelnummer: CSB-PA007564.50
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-CYPIIC8, Anti-Cytochrome P450 2C8, Anti-Cytochrome P450 IIC2, Anti-Cytochrome P450 MP-12, Anti-Cytochrome P450 MP-20,... |
| Anwendung: | ELISA, WB, IHC, IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
106,00 €
Anti-CYP2C8
Artikelnummer: CSB-PA694882.100
Host Species: Rabbit. Isotype: IgG. Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by...
| Schlagworte: | Anti-CYPIIC8, Anti-Cytochrome P450 2C8, Anti-Cytochrome P450 IIC2, Anti-Cytochrome P450 MP-12, Anti-Cytochrome P450 MP-20,... |
| Anwendung: | ELISA, WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
275,00 €
Cytochrome P450 2C8 (CYP2C8), human, recombinant
Artikelnummer: CSB-EP006418HU.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 27-490aa. Protein Length: Full Length of Mature Protein. Tag Info: N-terminal 10xHis-tagged and C-terminal Myc-tagged. Target Protein Sequence: RKLPPGPTPL PIIGNMLQID VKDICKSFTN FSKVYGPVFT VYFGMNPIVV FHGYEAVKEA LIDNGEEFSG RGNSPISQRI TKGLGIISSN...
| Schlagworte: | CYPIIC8, Cytochrome P450 2C8, Cytochrome P450 IIC2, Cytochrome P450 MP-20, Cytochrome P450 MP-12, Cytochrome P450 form 1,... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 60.1 kD |
ab 283,00 €
6alpha-hydroxy Paclitaxel-d5
Artikelnummer: Cay40926-1
An internal standard for the quantification of 6alpha-hydroxy paclitaxel 6alpha-hydroxy Paclitaxel-d5 is intended for use as an internal standard for the quantification of 6alpha-hydroxy paclitaxel (Cay-10009027) by GC- or LC-MS. 6alpha-hydroxy Paclitaxel is a metabolite of the antimitotic and anticancer agent...
| Schlagworte: | 6alpha-hydroxy Taxol-d5, (alphaR,betaS)-beta-(benzoyl-2,3,4,5,6-d5-amino)-alpha-hydroxy-benzenepropanoic acid,... |
| Anwendung: | GC-MS, LC-MS internal standard, quantification, paclitaxel metabolite |
| CAS | 1315376-90-9 |
| MW: | 874.9 D |
1.564,00 €
N-desethyl Amodiaquine (hydrochloride)
Artikelnummer: Cay20822-1
N-desethyl Amodiaquine is a primary metabolite of the antimalarial compound aminodiaquine (Cay-15954), produced by the action of cytochrome P450 isoform 2C8. N-desethyl Amodiaquine is highly active against P. falciparum and can synergize with amodiaquine.Formal Name:...
| Schlagworte: | 4-[(7-chloro-4-quinolinyl)amino]-2-[(ethylamino)methyl]-phenol, dihydrochloride |
| Anwendung: | Primary aminodiaquine metabolite |
| CAS | 79049-30-2 |
| MW: | 400.7 D |
ab 43,00 €
Carbamazepine 10,11-epoxide
Artikelnummer: Cay33908-5
Carbamazepine 10,11-epoxide is an active metabolite of the anticonvulsant carbamazepine. It is formed from carbamazepine by the cytochrome P450 (CYP) isoforms CYP3A4 and CYP2C8 in microsomes prepared from HepG2 cells expressing CYP3A4 or CYP2C8, respectively. Carbamazepine 10,11-epoxide has anticonvulsant activity...
| Schlagworte: | CBZ 10,11-epoxide, CBZ-E, 1a,10b-dihydro-6H-dibenz[b,f]oxireno[d]azepine-6-carboxamide |
| Anwendung: | Carbamazepine active metabolite |
| CAS | 36507-30-9 |
| MW: | 252.3 D |
ab 77,00 €
Anti-CYP2C8
Artikelnummer: NSJ-R34557-100UG
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Cytochrome P450 2C8 Protein function: Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway....
| Schlagworte: | Anti-CYP2C8, Anti-CYPIIC8, Anti-Cytochrome P450 2C8, Anti-Cytochrome P450 IIC2, Anti-Cytochrome P450 MP-12,... |
| Anwendung: | WB, ELISA (peptide) |
| Wirt: | Goat |
| Spezies-Reaktivität: | human |
755,00 €
N-desmethyl Rosiglitazone
Artikelnummer: Cay22103-1
N-desmethyl Rosiglitazone is a major metabolite of rosiglitazone (Cay-71740, Cay-71742, Cay-11884), a potent and selective PPARgamma ligand present in formulations that have been used to treat type 2 diabetes. Rosiglitazone is metabolized by the cytochrome P450 (CYP) isoform CYP2C8 to form N-desmethyl...
| Schlagworte: | SB-237216, 5-[[4-[2-(2-pyridinylamino)ethoxy]phenyl]methyl]-2,4-thiazolidinedione |
| Anwendung: | Rosiglitazone metabolite |
| CAS | 257892-31-2 |
| MW: | 343.4 D |
ab 139,00 €
Hydroxy Pioglitazone
Artikelnummer: Cay28043-1
Hydroxy pioglitazone is a major metabolite of the peroxisome proliferator-activated receptor gamma (PPARgamma) agonist pioglitazone (Cay-71745, Cay-22263, Cay-10028). It is formed from pioglitazone by the cytochrome P450 (CYP) isoform CYP2C8 with minor contributions from CYP3A4. Hydroxy pioglitazone binds to...
| Schlagworte: | 5-[[4-[2-[5-(1-hydroxyethyl)-2-pyridinyl]ethoxy]phenyl]methyl]-2,4-thiazolidinedione |
| Anwendung: | Major metabolite |
| CAS | 146062-44-4 |
| MW: | 372.4 D |
ab 369,00 €