Zu "K17712" wurden 56 Artikel gefunden!
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Dehydro Aripiprazole (hydrochloride)
Artikelnummer: TGM-T36664-10mg
Description: Dehydro aripiprazole is the primary, active metabolite of aripiprazole, an atypical antipsychotic. The metabolite is produced from the parent compound by the actions of cytochrome P450 (CYP) isoforms CYP3A4 and CYP2D6. Dehydro aripiprazole has similar pharmacological properties to aripiprazole. Target:...
| Anwendung: | Aripiprazole metabolite |
| CAS | 1008531-60-9 |
| MW: | 482.83 D |
ab 237,00 €
Endoxifen
Artikelnummer: TGM-T4281-10mg
Description: (E/Z)-Endoxifen ((E/Z)-Endoxifen) is an active metabolite of tamoxifen produced by the sequential action of cytochrome P450 (CYP) isoforms, including CYP2D6. It is a strong anti-estrogen, as it has an approximately 100-fold greater affinity for estrogen receptors than tamoxifen. As the efficient...
| Schlagworte: | (E/Z)-N-desmethyl-4-hydroxy Tamoxifen, (E/Z)-Endoxifen |
| Anwendung: | Tamoxifen metabolite |
| CAS | 110025-28-0 |
| MW: | 373.49 D |
ab 41,00 €
Promethazine Sulfoxide
Artikelnummer: TGM-T83896-10mg
Description: Promethazine sulfoxide, a metabolite of the histamine H1 receptor antagonist promethazine, is produced via the action of the cytochrome P450 (CYP) isoform CYP2D6, converting promethazine into this compound. Smiles: O=S1C2=C(N(CC(C)N(C)C)C3=C1C=CC=C3)C=CC=C2
| Anwendung: | Promethazine metabolite |
| CAS | 7640-51-9 |
| MW: | 300.42 D |
ab 237,00 €
4-hydroxy Nebivolol hydrochloride
Artikelnummer: TGM-T85245-10mg
Description: 4-Hydroxy Nebivolol, a primary metabolite of Nebivolol, results from the enzymatic hydroxylation of Nebivolol by the cytochrome P450 (CYP) isoform CYP2D6. Target: Others. Smiles: OC1C=2C(OC(C(CNCC(O)C3OC=4C(CC3)=CC(F)=CC4)O)C1)=CC=C(F)C2.Cl
| Anwendung: | Major nebivolol metabolite |
| CAS | 2717115-85-8 |
| MW: | 457.9 D |
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Des(benzylpyridyl) Atazanavi
Artikelnummer: TGM-T1883-100mg
Description: The N-dealkylated metabolite (M1) of Atazanavir, a HIV protease inhibitor. Target: HIV Protease. Smiles: [C@@H](CC1=CC=CC=C1)(NC([C@@H](NC(OC)=O)[C@@](C)(C)C)=O)[C@H](CNNC([C@@H](NC(OC)=O)C(C)(C)C)=O)O. References: Gianotti N, et al. New Microbiol. 2007 Apr,30(2):79-88.
| Anwendung: | Major metabolite |
| CAS | 1192224-24-0 |
| MW: | 537.65 D |
ab 39,00 €
N-Desmethyltamoxifen hydrochloride
Artikelnummer: TGM-T12148-100mg
Description: N-Desmethyltamoxifen hydrochloride is the primary metabolite of tamoxifen in humans. Target: Endogenous Metabolite, PKC, Estrogen Receptor/ERR. Smiles: Cl.CC\C(=C(/c1ccccc1)c1ccc(OCCNC)cc1)c1ccccc1
| Anwendung: | Tamoxifen active metabolite |
| CAS | 15917-65-4 |
| MW: | 393.95 D |
ab 35,00 €
(Z)-10-Hydroxynortriptyline
Artikelnummer: TGM-T13377-1mg
Description: (Z)-10-Hydroxy Nortriptyline is a Nortriptyline metabolite, and is a tricyclic antidepressant,and is used to relieve the symptoms of depression. Target: IL Receptor. Smiles: C(\CCNC)=C/1\C=2C(C(O)CC=3C1=CC=CC3)=CC=CC2. References: Shimoda K, et al. The impact of CYP2C19 and CYP2D6 genotypes on...
| Schlagworte: | (Z)-10-Hydroxy Nortriptyline |
| Anwendung: | Amitriptyline / nortriptyline active metabolite |
| CAS | 47132-19-4 |
| MW: | 279.38 D |
210,00 €
-30 %
Rabattaktion
Anti-CYP2D6
Artikelnummer: ARG44589.50
Protein function: A cytochrome P450 monooxygenase involved in the metabolism of fatty acids, steroids and retinoids (PubMed:18698000, PubMed:19965576, PubMed:20972997, PubMed:21289075, PubMed:21576599). Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a...
| Schlagworte: | Anti-CYP2DL1, Anti-CYPIID6, Anti-CYPIID6, Anti-Cytochrome P450-DB1, Anti-Cytochrome P450-DB1, Anti-Debrisoquine... |
| Anwendung: | IHC (paraffin), WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
520,00 €
364,00 €
Anti-CYP2D6
Artikelnummer: CSB-PA001959.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-CYPIID6, Anti-CYP2DL1, Anti-Cytochrome P450-DB1, Anti-Cytochrome P450 2D6, Anti-Cholesterol 25-hydroxylase,... |
| Anwendung: | ELISA, WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 106,00 €
Anti-CYP2D6
Artikelnummer: CSB-PA001966.50
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-CYPIID6, Anti-CYP2DL1, Anti-Cytochrome P450-DB1, Anti-Cytochrome P450 2D6, Anti-Cholesterol 25-hydroxylase,... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
106,00 €
Anti-CYP2D6
Artikelnummer: CSB-PA028466.100
Host Species: Rabbit. Isotype: IgG. Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by...
| Schlagworte: | Anti-CYPIID6, Anti-CYP2DL1, Anti-Cytochrome P450-DB1, Anti-Cytochrome P450 2D6, Anti-Cholesterol 25-hydroxylase,... |
| Anwendung: | ELISA, WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
275,00 €
Anti-CYP2D6
Artikelnummer: CSB-PA051152.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: CYP2D6. Antigen Species: Human
| Schlagworte: | Anti-CYPIID6, Anti-CYP2DL1, Anti-Cytochrome P450-DB1, Anti-Cytochrome P450 2D6, Anti-Cholesterol 25-hydroxylase,... |
| Anwendung: | ELISA, WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 163,00 €