Zu "K17709" wurden 31 Artikel gefunden!
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8-hydroxy Efavirenz
Artikelnummer: TGM-T37162-1mg
Description: 8-hydroxy Efavirenz is a major oxidative metabolite of the non-nucleoside reverse transcriptase inhibitor efavirenz . 8-hydroxy Efavirenz is formed when efavirenz is metabolized by the cytochrome P450 (CYP) isoform CYP2B6. It induces apoptosis in rat primary hippocampal neurons and loss of dendritic...
| Anwendung: | Oxidative metabolite |
| CAS | 205754-33-2 |
| MW: | 331.68 D |
1.481,00 €
4-Hydroxytamoxifen
Artikelnummer: TGM-T4420-100mg
Description: 4-Hydroxytamoxifen (ICI 79280) is the active metabolite of Tamoxifen, an estrogen receptor modulator (SERM) with selective and oral potency. 4-Hydroxytamoxifen has antitumor activity and may be used in breast cancer research. Target: Estrogen/progestogen Receptor, Estrogen Receptor/ERR. Smiles:...
| Schlagworte: | (Z)-4-hydroxy Tamoxifen, ICI 79280, trans-4-Hydroxytamoxifen |
| Anwendung: | Tamoxifen metabolite |
| CAS | 68047-06-3 |
| MW: | 387.51 D |
ab 53,00 €
Cedrol
Artikelnummer: TGM-T5594-1mL
Description: Cedrol is a cedrane sesquiterpenoid and a tertiary alcohol,Cedrol inhibits the cytochrome P450 (CYP) isoforms CYP2B6 and CYP3A4 (Kis = 0.9 and 3.4 µM, respectively). Target: Antifungal, P450. Smiles: [H][C@@]12CC[C@@H](C)[C@@]11C[C@]([H])(C2(C)C)[C@](C)(O)CC1. References: CHENG, SenSung, CHUNG, et al....
| Anwendung: | Bioactive sesquiterpene alcohol, CYP2B6 & CYP3A4 inhibitor |
| CAS | 77-53-2 |
| MW: | 222.37 D |
ab 30,00 €
2-Phenyl-2-(1-piperidinyl)propane
Artikelnummer: TGM-T7788-100mg
Description: 2-Phenyl-2-(1-piperidinyl)propane (PPP), an analog of phencyclidine, is a chemical compound. Target: Others. Smiles: CC(C)(N1CCCCC1)c1ccccc1. References: Chun J , Kent U M , Moss R M , et al. Mechanism-based inactivation of cytochromes P450 2B1 and P450 2B6 by 2- phenyl-2-(1-piperidinyl) propane[J]....
| Anwendung: | CYP2B6 inactivator |
| CAS | 92321-29-4 |
| MW: | 203.32 D |
ab 47,00 €
(1R,4R)-N-desmethyl Sertraline hydrochloride
Artikelnummer: TGM-T84956-10mg
Description: "(1R,4R)-N-desmethyl Sertraline, a metabolite of the selective serotonin reuptake inhibitor (SSRI) sertraline, plays a key role in its pharmacological effects.". Target: Others. Smiles: N[C@H]1C=2C([C@H](CC1)C3=CC(Cl)=C(Cl)C=C3)=CC=CC2.Cl
| Schlagworte: | (1R,4R)-N-demethyl Sertraline |
| Anwendung: | Sertraline metabolite |
| CAS | 675126-09-7 |
| MW: | 328.66 D |
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Anti-CYP2B6
Artikelnummer: CSB-PA001956.50
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-CYPIIB6, Anti-Cytochrome P450 2B6, Anti-Cytochrome P450 IIB1, Anti-1,4-cineole 2-exo-monooxygenase, 1,4 cineole 2 exo... |
| Anwendung: | ELISA, WB, IHC, IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
106,00 €
Anti-CYP2B6
Artikelnummer: CSB-PA007566.50
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-CYPIIB6, Anti-Cytochrome P450 2B6, Anti-Cytochrome P450 IIB1, Anti-1,4-cineole 2-exo-monooxygenase, 1,4 cineole 2 exo... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
106,00 €
Anti-CYP2B6
Artikelnummer: CSB-PA212733.100
Host Species: Rabbit. Isotype: IgG. Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by...
| Schlagworte: | Anti-CYPIIB6, Anti-Cytochrome P450 2B6, Anti-Cytochrome P450 IIB1, Anti-1,4-cineole 2-exo-monooxygenase, 1,4 cineole 2 exo... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
275,00 €
Anti-CYP2B6
Artikelnummer: CSB-PA254762.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: CYP2B6. Antigen Species: Human
| Schlagworte: | Anti-CYPIIB6, Anti-Cytochrome P450 2B6, Anti-Cytochrome P450 IIB1, Anti-1,4-cineole 2-exo-monooxygenase, 1,4 cineole 2 exo... |
| Anwendung: | ELISA, WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 163,00 €
Anti-CYP2B6
Artikelnummer: CSB-PA289766.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: CYP2B6. Antigen Species: Human
| Schlagworte: | Anti-CYPIIB6, Anti-Cytochrome P450 2B6, Anti-Cytochrome P450 IIB1, Anti-1,4-cineole 2-exo-monooxygenase, 1,4 cineole 2 exo... |
| Anwendung: | ELISA, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 163,00 €
(Z)-4-hydroxy Tamoxifen
Artikelnummer: Cay14854-1
(Z)-4-hydroxy Tamoxifen is an active metabolite of the estrogen receptor (ER) modulator tamoxifen (Cay-13258). It is primarily formed from tamoxifen by the cytochrome P450 (CYP) isoforms CYP2D6 and CYP2B6. (Z)-4-hydroxy Tamoxifen (10 nM) decreases progesterone receptor (PR) mRNA expression induced by the estrogen...
| Schlagworte: | trans-4-hydroxy Tamoxifen, ICI 79280, 4-[(1Z)-1-[4-[2-(dimethylamino)ethoxy]phenyl]-2-phenyl-1-buten-1-yl]-phenol |
| Anwendung: | Tamoxifen metabolite |
| CAS | 68047-06-3 |
| MW: | 387.5 D |
ab 50,00 €
2-Phenyl-2-(1-piperidinyl)propane
Artikelnummer: Cay17799-10
2-Phenyl-2-(1-piperidinyl)propane is an analog of phencyclidine that acts as a mechanism-based inactivator of human cytochrome P450 (CYP) 2B6 (Ki = 5.6 µM, IC50 = 5.1 µM). It is 15-fold more selective for inhibition of CYP2B6 over CYP2D6 and 40-60-fold more selective for CYP2B6 over CYP1A2, CYP2A6, CYP2Cs, and...
| Schlagworte: | 1-(alpha,alpha-dimethylbenzyl)-Piperidine, PPP, 1-(1-methyl-1-phenylethyl)-piperidine |
| Anwendung: | CYP2B6 inactivator |
| CAS | 92321-29-4 |
| MW: | 203.3 D |
ab 60,00 €