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LDN-192960 hydrochloride
LDN-192960 hydrochloride

Artikelnummer: TGM-T11830-100mg

Description: LDN-192960 hydrochloride is an inhibitor of Dual-specificity Tyrosine-regulated Kinase 2 (DYRK2) and Haspin, with IC50 values of 48 nM and 10 nM, respectively. Target: Others. Smiles: COC1=CC2=C(C=C1)N=C3C=CC(OC)=CC3=C2SCCCN.Cl.Cl. References: Cuny GD, et al. Structure-activity relationship study of...
Anwendung: HASPIN / DYRK2 inhibitor
CAS 2309172-48-1
MW: 401.35 D
ab 750,00 €
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CHR-6494
CHR-6494

Artikelnummer: TGM-T14959-100mg

Description: CHR-6494 is a haspin inhibitor that inhibits histone H3T3 phosphorylation (IC50: 2 nM). Target: Others. Smiles: OC(=O)C(F)(F)F.CCCNc1ccc2ncc(-c3ccc4[nH]ncc4c3)n2n1. References: Huertas D, et al. Antitumor activity of a small-molecule inhibitor of the histone kinase Haspin. Oncogene. 2012 Mar...
Anwendung: Haspin Kinase Inhibitor
CAS 1333377-65-3
MW: 292.34 D
ab 52,00 €
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Anti-Haspin
Anti-Haspin

Artikelnummer: A302-241A

Protein function: Serine/threonine-protein kinase that phosphorylates histone H3 at 'Thr-3' (H3T3ph) during mitosis. This positions and activates AURKB and other components of the chromosomal passenger complex (CPC) at centromeres to ensure proper chromatid cohesion, metaphase alignment and normal progression...
Schlagworte: Anti-GSG2, Anti-H-haspin, EC=2.7.11.1, Anti-Germ cell-specific gene 2 protein, Anti-Serine/threonine-protein kinase...
Anwendung: WB, IP, IHC
Wirt: Rabbit
Spezies-Reaktivität: human
ab 164,00 €
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LDN-192960 (hydrochloride)
LDN-192960 (hydrochloride)

Artikelnummer: Cay19089-10

LDN-192960 is an inhibitor of haspin protein kinase and dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 (DYRK2) with IC50 values of 10 and 48 nM, respectively. It is selective for haspin and DYRK2 over TRKB, CLK1, DYRK1A, DYRK3, ROS, HIPK1, HIPK2, PIM-1, and PIM-2 kinases (IC50s = 720-91,000...
Schlagworte: 3-[(2,7-dimethoxy-9-acridinyl)thio]-1-propanamine, dihydrochloride
Anwendung: HASPIN / DYRK2 inhibitor
CAS 2309172-48-1
MW: 401.4 D
ab 130,00 €
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CHR-6494
CHR-6494

Artikelnummer: Cay11478-1

CHR-6494 is a haspin protein kinase inhibitor (IC50 = 2 nM) selective over 27 other protein kinases, including Aurora B kinase (IC50 > 1 µM). Haspin is a kinase necessary for mitosis that selectively phosphorylates histone 3 at the threonine 3 residue (H3T3ph). CHR-6494 decreases phosphorylation of H3T3 and arrests...
Schlagworte: 3-(1H-indazol-5-yl)-N-propyl-imidazo[1,2-b]pyridazin-6-amine
Anwendung: Haspin Kinase Inhibitor
CAS 1333377-65-3
MW: 292.3 D
ab 43,00 €
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Anti-HASPIN
Anti-HASPIN

Artikelnummer: E-AB-18068.120

Serine/threonine-protein kinase that phosphorylates histone H3 at 'Thr-3' (H3T3ph) during mitosis. This positions and activates AURKB and other components of the chromosomal passenger complex (CPC) at centromeres to ensure proper chromatid cohesion, metaphase alignment and normal progression through the cell cycle....
Schlagworte: Anti-H-haspin, EC=2.7.11.1, Anti-Germ cell-specific gene 2 protein, Anti-Serine/threonine-protein kinase haspin,...
Anwendung: IHC, ELISA
Wirt: Rabbit
Spezies-Reaktivität: human
ab 71,00 €
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Anti-HASPIN
Anti-HASPIN

Artikelnummer: E-AB-19975.120

Serine/threonine-protein kinase that phosphorylates histone H3 at 'Thr-3' (H3T3ph) during mitosis. This positions and activates AURKB and other components of the chromosomal passenger complex (CPC) at centromeres to ensure proper chromatid cohesion, metaphase alignment and normal progression through the cell cycle....
Schlagworte: Anti-H-haspin, EC=2.7.11.1, Anti-Germ cell-specific gene 2 protein, Anti-Serine/threonine-protein kinase haspin,...
Anwendung: IHC, ELISA
Wirt: Rabbit
Spezies-Reaktivität: human
ab 71,00 €
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Anti-GSG2
Anti-GSG2

Artikelnummer: ATA-HPA027422.100

Protein function: Serine/threonine-protein kinase that phosphorylates histone H3 at 'Thr-3' (H3T3ph) during mitosis. May act through H3T3ph to both position and modulate activation of AURKB and other components of the chromosomal passenger complex (CPC) at centromeres to ensure proper chromatid cohesion, metaphase...
Schlagworte: Anti-H-haspin, Anti-Germ cell-specific gene 2 protein, Anti-Serine/threonine-protein kinase haspin, Anti-Haploid germ...
Anwendung: WB, IHC
Wirt: Rabbit
Spezies-Reaktivität: human
ab 300,00 €
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Anti-GSG2
Anti-GSG2

Artikelnummer: ATA-HPA030698.100

Protein function: Serine/threonine-protein kinase that phosphorylates histone H3 at 'Thr-3' (H3T3ph) during mitosis. May act through H3T3ph to both position and modulate activation of AURKB and other components of the chromosomal passenger complex (CPC) at centromeres to ensure proper chromatid cohesion, metaphase...
Schlagworte: Anti-H-haspin, Anti-Germ cell-specific gene 2 protein, Anti-Serine/threonine-protein kinase haspin, Anti-Haploid germ...
Anwendung: ICC
Wirt: Rabbit
Spezies-Reaktivität: human
ab 300,00 €
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PhosphoSens Kinase Sensor Peptide
PhosphoSens Kinase Sensor Peptide

Artikelnummer: AQT-CSKS-AQT0798B

Bulk Sensor Peptide Substrate recommended for HASPIN PhosphoSens-Kinetic assays and HASPIN PhosphoSens-Red assays
Schlagworte: HASPIN
3.744,00 €
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PhosphoSens Kinase Sensor Peptide
PhosphoSens Kinase Sensor Peptide

Artikelnummer: AQT-CSKS-AQT0798K

PhosphoSens Kinase Assay Kit recommended for HASPIN PhosphoSens-Kinetic assays
Schlagworte: HASPIN
837,00 €
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PhosphoSens Kinase Sensor Peptide
PhosphoSens Kinase Sensor Peptide

Artikelnummer: AQT-CSKS-AQT0798KR

PhosphoSens Kinase Assay Kit recommended for HASPIN PhosphoSens-Red assays
Schlagworte: HASPIN
837,00 €
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