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Zu "K16315" wurden 19 Artikel gefunden!
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Artikelnummer: TGM-T11830-100mg
Description: LDN-192960 hydrochloride is an inhibitor of Dual-specificity Tyrosine-regulated Kinase 2 (DYRK2) and Haspin, with IC50 values of 48 nM and 10 nM, respectively. Target: Others. Smiles: COC1=CC2=C(C=C1)N=C3C=CC(OC)=CC3=C2SCCCN.Cl.Cl. References: Cuny GD, et al. Structure-activity relationship study of...
Anwendung: | HASPIN / DYRK2 inhibitor |
CAS | 2309172-48-1 |
MW: | 401.35 D |
ab 750,00 €
Artikelnummer: TGM-T14959-100mg
Description: CHR-6494 is a haspin inhibitor that inhibits histone H3T3 phosphorylation (IC50: 2 nM). Target: Others. Smiles: OC(=O)C(F)(F)F.CCCNc1ccc2ncc(-c3ccc4[nH]ncc4c3)n2n1. References: Huertas D, et al. Antitumor activity of a small-molecule inhibitor of the histone kinase Haspin. Oncogene. 2012 Mar...
Anwendung: | Haspin Kinase Inhibitor |
CAS | 1333377-65-3 |
MW: | 292.34 D |
ab 52,00 €
Artikelnummer: A302-241A
Protein function: Serine/threonine-protein kinase that phosphorylates histone H3 at 'Thr-3' (H3T3ph) during mitosis. This positions and activates AURKB and other components of the chromosomal passenger complex (CPC) at centromeres to ensure proper chromatid cohesion, metaphase alignment and normal progression...
Schlagworte: | Anti-GSG2, Anti-H-haspin, EC=2.7.11.1, Anti-Germ cell-specific gene 2 protein, Anti-Serine/threonine-protein kinase... |
Anwendung: | WB, IP, IHC |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
ab 164,00 €
Artikelnummer: Cay19089-10
LDN-192960 is an inhibitor of haspin protein kinase and dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 (DYRK2) with IC50 values of 10 and 48 nM, respectively. It is selective for haspin and DYRK2 over TRKB, CLK1, DYRK1A, DYRK3, ROS, HIPK1, HIPK2, PIM-1, and PIM-2 kinases (IC50s = 720-91,000...
Schlagworte: | 3-[(2,7-dimethoxy-9-acridinyl)thio]-1-propanamine, dihydrochloride |
Anwendung: | HASPIN / DYRK2 inhibitor |
CAS | 2309172-48-1 |
MW: | 401.4 D |
ab 130,00 €
Artikelnummer: Cay11478-1
CHR-6494 is a haspin protein kinase inhibitor (IC50 = 2 nM) selective over 27 other protein kinases, including Aurora B kinase (IC50 > 1 µM). Haspin is a kinase necessary for mitosis that selectively phosphorylates histone 3 at the threonine 3 residue (H3T3ph). CHR-6494 decreases phosphorylation of H3T3 and arrests...
Schlagworte: | 3-(1H-indazol-5-yl)-N-propyl-imidazo[1,2-b]pyridazin-6-amine |
Anwendung: | Haspin Kinase Inhibitor |
CAS | 1333377-65-3 |
MW: | 292.3 D |
ab 43,00 €
Artikelnummer: E-AB-18068.120
Serine/threonine-protein kinase that phosphorylates histone H3 at 'Thr-3' (H3T3ph) during mitosis. This positions and activates AURKB and other components of the chromosomal passenger complex (CPC) at centromeres to ensure proper chromatid cohesion, metaphase alignment and normal progression through the cell cycle....
Schlagworte: | Anti-H-haspin, EC=2.7.11.1, Anti-Germ cell-specific gene 2 protein, Anti-Serine/threonine-protein kinase haspin,... |
Anwendung: | IHC, ELISA |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
ab 71,00 €
Artikelnummer: E-AB-19975.120
Serine/threonine-protein kinase that phosphorylates histone H3 at 'Thr-3' (H3T3ph) during mitosis. This positions and activates AURKB and other components of the chromosomal passenger complex (CPC) at centromeres to ensure proper chromatid cohesion, metaphase alignment and normal progression through the cell cycle....
Schlagworte: | Anti-H-haspin, EC=2.7.11.1, Anti-Germ cell-specific gene 2 protein, Anti-Serine/threonine-protein kinase haspin,... |
Anwendung: | IHC, ELISA |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
ab 71,00 €
Artikelnummer: ATA-HPA027422.100
Protein function: Serine/threonine-protein kinase that phosphorylates histone H3 at 'Thr-3' (H3T3ph) during mitosis. May act through H3T3ph to both position and modulate activation of AURKB and other components of the chromosomal passenger complex (CPC) at centromeres to ensure proper chromatid cohesion, metaphase...
Schlagworte: | Anti-H-haspin, Anti-Germ cell-specific gene 2 protein, Anti-Serine/threonine-protein kinase haspin, Anti-Haploid germ... |
Anwendung: | WB, IHC |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
ab 300,00 €
Artikelnummer: ATA-HPA030698.100
Protein function: Serine/threonine-protein kinase that phosphorylates histone H3 at 'Thr-3' (H3T3ph) during mitosis. May act through H3T3ph to both position and modulate activation of AURKB and other components of the chromosomal passenger complex (CPC) at centromeres to ensure proper chromatid cohesion, metaphase...
Schlagworte: | Anti-H-haspin, Anti-Germ cell-specific gene 2 protein, Anti-Serine/threonine-protein kinase haspin, Anti-Haploid germ... |
Anwendung: | ICC |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
ab 300,00 €
Artikelnummer: AQT-CSKS-AQT0798B
Bulk Sensor Peptide Substrate recommended for HASPIN PhosphoSens-Kinetic assays and HASPIN PhosphoSens-Red assays
Schlagworte: | HASPIN |
3.744,00 €
Artikelnummer: AQT-CSKS-AQT0798K
PhosphoSens Kinase Assay Kit recommended for HASPIN PhosphoSens-Kinetic assays
Schlagworte: | HASPIN |
837,00 €
Artikelnummer: AQT-CSKS-AQT0798KR
PhosphoSens Kinase Assay Kit recommended for HASPIN PhosphoSens-Red assays
Schlagworte: | HASPIN |
837,00 €