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Zu "K15729" wurden 36 Artikel gefunden!
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Artikelnummer: CSB-CF018976MO.100
Organism: Mus musculus (Mouse). Source: in vitro E.coli expression system. Expression Region: 1-153aa. Protein Length: Full Length. Tag Info: N-terminal 10xHis-SUMO-tagged. Target Protein Sequence: MPSPGLVMES GQVLPAFLLC STLLVIKMYA VAVITGQMRL RKKAFANPED ALKRGGLQYY RSDPDVERCL RAHRNDMETI YPFLFLGFVY SFLGPNPLIA...
Schlagworte: | Pges, Ptges, mPGES-1, Prostaglandin E synthase, Glutathione peroxidase PTGES, Glutathione transferase PTGES, Microsomal... |
Anwendung: | Activity not tested |
Exprimiert in: | E.coli in vitro |
Ursprungsart: | mouse |
MW: | 35.8 kD |
ab 1.413,00 €
Artikelnummer: CSB-PA003751.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
Schlagworte: | Anti-PTGES, Anti-MPGES-1, Anti-MGST1-L1, Anti-Prostaglandin E synthase, Anti-p53-induced gene 12 protein, Anti-Glutathione... |
Anwendung: | ELISA, WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse, rat |
ab 106,00 €
Artikelnummer: Cay37925-1
Vipoglanstat is an inhibitor of microsomal prostaglandin E synthase-1 (mPGES-1, IC50 = =0.5 nM in isolated human whole blood). It reduces LPS-induced increases in the influx of neutrophils and levels of cytokines in bronchoalveolar lavage fluid (BALF), as well as the expression of PTGES, the gene encoding mPGES-1,...
Schlagworte: | BI 1029539, GS-248, OX-MPI,... |
Anwendung: | mPGES-1 inhibitor |
CAS | 1360622-01-0 |
MW: | 678.5 D |
ab 267,00 €
Artikelnummer: Cay160140-1
Prostaglandin E Synthase-1 (PGES-1) catalyzes the isomerization of PGH2 (Cay-17020) to PGE2 (Cay-14010). PGE2 is one of the primary COX products of arachidonic acid (Cay-90010) and one of the most widely investigated prostaglandins. Its activity influences inflammation, fertility and parturition, gastric mucosal...
Schlagworte: | Anti-PTGES, Anti-Prostaglandin E synthase, Anti-Prostaglandin E synthase, Anti-Glutathione peroxidase PTGES,... |
Anwendung: | IF, WB |
Wirt: | Rabbit |
422,00 €
Artikelnummer: ELK-ELK2327.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human PTGES. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human PTGES. Next,...
Schlagworte: | PTGES, MPGES-1, MGST1-L1, Prostaglandin E synthase, p53-induced gene 12 protein, Glutathione peroxidase PTGES, Glutathione... |
Anwendung: | ELISA |
Spezies-Reaktivität: | human |
ab 365,00 €
Artikelnummer: ELK-ELK4721.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat PTGES. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat PTGES. Next,...
Schlagworte: | Ptges, mPGES-1, Prostaglandin E synthase, Glutathione peroxidase PTGES, Glutathione transferase PTGES, Inducible... |
Anwendung: | ELISA |
Spezies-Reaktivität: | rat |
ab 365,00 €
Artikelnummer: Cay15129-1
Microsomal prostaglandin E synthase-1 (mPGES-1) converts the COX product PGH2 into the biologically active PGE2. Like COX-2, the expression of mPGES-1 is induced in response to pro-inflammatory mediators, including LPS, IL-1beta, and TNF-alpha. CAY10678 is a benzoimidazole that potently inhibits human and rat...
Schlagworte: | mPGES-1 Inhibitor III, N-cyclopentyl-1-[5,6-dimethyl-1-(1-methylethyl)-1H-benzimidazol-2-yl]-4-piperidinecarboxamide |
Anwendung: | mPGES-1 inhibitor |
CAS | 1268709-57-4 |
MW: | 382.5 D |
ab 84,00 €
Artikelnummer: Cay13217-1
Microsomal prostaglandin E2 synthase-1 (mPGES-1) is the terminal enzyme in the biosynthesis of PGE2. MF63 is a potent, selective, and orally active inhibitor of human mPGES-1 (IC50 = 1.3 nM). It displays greater than 1,000-fold selectivity over other prostanoid synthases. MF63 also potently inhibits guinea pig...
Schlagworte: | 2-(9-chloro-1H-phenanthro[9,10-d]imidazol-2-yl)-1,3-benzenedicarbonitrile |
Anwendung: | mPGES-1 inhibitor |
CAS | 892549-43-8 |
MW: | 378.8 D |
ab 46,00 €
Artikelnummer: Cay13665-1
Microsomal prostaglandin E2 synthase-1 (mPGES-1), with cyclooxygenase-2 (COX-2), synthesizes PGE2, which is directly involved in signaling during inflammation, fever, and pain. 5-Lipoxygenase (5-LO) initiates the synthesis of leukotrienes (LTs), which are pro-inflammatory mediators. YS-121 is a dual inhibitor of...
Schlagworte: | 2-[[4-chloro-6-[(2,3-dimethylphenyl)amino]-2-pyrimidinyl]thio]-octanoic acid |
Anwendung: | mPGES-1/5-LO inhibitor |
CAS | 916482-17-2 |
MW: | 408 D |
ab 74,00 €
Artikelnummer: Cay18904-1
Microsomal prostaglandin E synthase-1 (mPGES-1) converts the COX product prostaglandin H2 (PGH2, Cay-17020) into the biologically active PGE2 (Cay-14010). Like COX-2, the expression of mPGES-1 is induced in response to pro-inflammatory mediators, including LPS, IL-1beta, and TNF-alpha. PF-9184 is a potent inhibitor...
Schlagworte: | N-(3',4'-dichloro[1,1'-biphenyl]-4-yl)-4-hydroxy-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide |
Anwendung: | mPGES-1 inhibitor |
CAS | 1221971-47-6 |
MW: | 461.3 D |
ab 60,00 €
Artikelnummer: Cay18905-1
Prostaglandin E2 (PGE2, Cay-14010) is the major PG synthesized at sites of inflammation and plays an important role in different inflammatory diseases. It acts as a mediator of pain and inflammation and promotes bone destruction. The increased synthesis of PGE2 during inflammation can be accounted for by increased...
Schlagworte: | 2-chloro-5-[[(2,2-dimethyl-1-oxopropyl)amino]methyl]-N-1H-imidazol-2-yl-benzamide |
Anwendung: | mPGES-1 inhibitor |
CAS | 1381846-21-4 |
MW: | 334.8 D |
ab 77,00 €
Artikelnummer: Cay22768-1
PF-4693627 is an orally bioavailable inhibitor of microsomal prostaglandin E (PGE) synthase-1 (mPGES-1, IC50 = 3 nM). It is selective for mPGES-1 over PGDS, TXAS, and 5-LO in HWB-1483 cells, which have IC50 values greater than 50 µM, as well as COX-2 in fetal fibroblasts (IC50 = >10 µM). PF-4693627 inhibits...
Schlagworte: | 1-[5-chloro-6-(4-chlorophenyl)-2-benzoxazolyl]-N-[(1S,3S)-3-(hydroxymethyl)cyclohexyl]-4-piperidinecarboxamide |
Anwendung: | mPGES-1 inhibitor |
CAS | 1312815-93-2 |
MW: | 502.4 D |
ab 50,00 €