Zu "K15680" wurden 60 Artikel gefunden!
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Anti-HSD11B1
Artikelnummer: ABS-KC-3295.100
Protein function: Catalyzes reversibly the conversion of cortisol to the inactive metabolite cortisone (PubMed:10497248). Catalyzes reversibly the conversion of 7-ketocholesterol to 7-beta-hydroxycholesterol. In intact cells, the reaction runs only in one direction, from 7- ketocholesterol to...
| Schlagworte: | Anti-11-beta-hydroxysteroid dehydrogenase 1, Anti-11-DH, Anti-11-beta-HSD1, Anti-7-oxosteroid reductase,... |
| Anwendung: | IHC |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
ab 206,00 €
Anti-HSD11B1
Artikelnummer: ABS-KC-3946.100
Protein function: Catalyzes reversibly the conversion of cortisol to the inactive metabolite cortisone (PubMed:10497248). Catalyzes reversibly the conversion of 7-ketocholesterol to 7-beta-hydroxycholesterol. In intact cells, the reaction runs only in one direction, from 7- ketocholesterol to...
| Schlagworte: | Anti-11-beta-hydroxysteroid dehydrogenase 1, Anti-11-DH, Anti-11-beta-HSD1, Anti-7-oxosteroid reductase,... |
| Anwendung: | IP |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human, mouse |
ab 206,00 €
11beta-Hydroxysteroid Dehydrogenase (human, recombinant)
Artikelnummer: Cay10007815-100
11beta-Hydroxysteroid dehydrogenase (11beta-HSD) exists as two isozymes 11beta-HSD1 and 11beta-HSD2. Both isoforms are members of the short-chain dehydrogenase/reductase (SDRs) family. 11beta-HSD1 is a membrane-bound glycoprotein localized on the endoplasmic reticulum. The main catalytic domain of 11beta-HSD1 lies...
| Schlagworte: | HSD11, 11-DH, 11-DH, 11-beta-HSD1, 11-beta-HSD1, 11-beta-hydroxysteroid dehydrogenase 1, 11-beta-hydroxysteroid... |
| Anwendung: | Enzyme activity, WB |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 31,4 kD |
664,00 €
Ammonium glycyrrhizinate
Artikelnummer: TGM-T2891-1mL
Description: Ammonium glycyrrhizinate (Glycyrram) exhibits diverse pharmacological properties, including anti-inflammatory, antiallergic, antigastriculcer, and antihepatitis activities. Target: Others. Smiles:...
| Schlagworte: | Monoammonium glycyrrhizinate hydrate, Glycyrram, Glycamil, Ammonium Glycyrrhizate, Monoammonium glycyrrhizinate |
| Anwendung: | Targets corticosteroid 11-beta-dehydrogenase isozyme 1 [EC:1.1.1.146] (HSD11B1) |
| CAS | 53956-04-0 |
| MW: | 839.97 D |
ab 42,00 €
BVT-14225
Artikelnummer: TGM-T3542-100mg
Description: BVT-14225, a selective 11beta-Hydroxysteroid dehydrogenase type 1 (11beta-HSD1) inhibitor, has an IC50 value of 52 nM. Target: Dehydrogenase. Smiles: CCN(CC)C(=O)Cc1csc(NS(=O)(=O)c2cccc(Cl)c2C)n1. References: Barf T, et al. Arylsulfonamidothiazoles as a new class of potential antidiabetic drugs....
| Schlagworte: | BVT 14225 |
| Anwendung: | 11beta-HSD1 inhibitor |
| CAS | 376638-65-2 |
| MW: | 401.93 D |
ab 40,00 €
Dipotassium glycyrrhizinate
Artikelnummer: TGM-T5666-100mg
Description: Dipotassium glycyrrhizinate is an anionic surfactant having anti-allergic and anti-inflammatory activities. Target: Virus Protease. Smiles:...
| Anwendung: | Targets corticosteroid 11-beta-dehydrogenase isozyme 1 [EC:1.1.1.146] (HSD11B1) |
| CAS | 68797-35-3 |
| MW: | 899.12 D |
ab 31,00 €
11beta-HSD1-IN-12
Artikelnummer: TGM-T72814-100mg
Description: 11beta-HSD1-IN-12 is an 11beta-HSD1 inhibitor.11beta-HSD1-IN-12 is implicated in the conversion of glucocorticoids in vivo and can be used to study metabolic syndrome and obesity. Target: Dehydrogenase. Smiles: Cc1c(Cl)cccc1S(=O)(=O)N1CCC[C@@H](C1)C(=O)NC1CCCCC1. References: Wenqing Yao, et al....
| Anwendung: | 11beta-HSD1 inhibitor |
| CAS | 872506-67-7 |
| MW: | 398.95 D |
ab 194,00 €
Carbenoxolone
Artikelnummer: TGM-T7732-5mg
Description: Carbenoxolone (Biogastrone) is an inhibitor of 11beta-HSD and gap junction connexin channels. Carbenoxolone inhibits macrophage migration into atria and prevents the development of fatty liver disease. Target: Dehydrogenase, Gap Junction Protein. Smiles:...
| Schlagworte: | Carbenoxolone, Bioral, Biogastrone, Carbenoxolona |
| Anwendung: | Targets corticosteroid 11-beta-dehydrogenase isozyme 1 [EC:1.1.1.146] (HSD11B1) |
| CAS | 5697-56-3 |
| MW: | 570.76 D |
49,00 €
BI-187004
Artikelnummer: TGM-T9594-10mg
Description: BI-187004 is an 11beta-hydroxysteroid dehydrogenase 1 inhibitor. Target: Dehydrogenase. Smiles: C(=O)(N1[C@@]2([C@@](C=3C(C2)=CC=C(C#N)C3)(CCC1)[H])[H])C=4C=C5C(=CC4)N=CN5. References: Maw HH, et al. N-Methylation of BI 187004 by Thiol S-Methyltransferase. Drug Metab Dispos. 2018 Jun,46(6):770-778.
| Anwendung: | 11beta-HSD1 inhibitor |
| CAS | 1303515-32-3 |
| MW: | 342.39 D |
ab 72,00 €
HSD11B1 Protein, Human, Recombinant (His & SUMO)
Artikelnummer: TGM-TMPH-00843-100ug
Description: Catalyzes reversibly the conversion of cortisol to the inactive metabolite cortisone. Catalyzes reversibly the conversion of 7-ketocholesterol to 7-beta-hydroxycholesterol. In intact cells, the reaction runs only in one direction, from 7-ketocholesterol to 7-beta-hydroxycholesterol. HSD11B1 Protein,...
| Schlagworte: | Short chain dehydrogenase/reductase family 26C member 1, HSD11B1, Corticosteroid 11-beta-dehydrogenase isozyme 1,... |
| MW: | 45.5 kD |
ab 198,00 €
BVT 14225
Artikelnummer: Cay41224-1
BVT 14225 is an inhibitor of 11beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD1, IC50s = 52 and 284 nM for the human and mouse enzymes, respectively). It is selective for human 11beta-HSD1 over human 11beta-HSD2 (IC50 = >10,000 nM). It inhibits 11beta-HSD1 by 55% in HEK293 cells expressing human HSD11B1, the...
| Schlagworte: | 2-[[(3-chloro-2-methylphenyl)sulfonyl]amino]-N,N-diethyl-4-thiazoleacetamide |
| Anwendung: | 11beta-HSD1 inhibitor |
| CAS | 376638-65-2 |
| MW: | 401.9 D |
ab 35,00 €
11-beta-Hydroxysteroid dehydrogenase 1 (HSD11B1),...
Artikelnummer: CSB-EP010763HU.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 25-292aa. Protein Length: Partial. Tag Info: N-terminal 6xHis-SUMO-tagged. Target Protein Sequence: EEFRPEMLQG KKVIVTGASK GIGREMAYHL AKMGAHVVVT ARSKETLQKV VSHCLELGAA SAHYIAGTME DMTFAEQFVA QAGKLMGGLD MLILNHITNT SLNLFHDDIH HVRKSMEVNF LSYVVLTVAA...
| Schlagworte: | HSD11, 11-DH, 11-beta-HSD1, 11-beta-hydroxysteroid dehydrogenase 1, Corticosteroid 11-beta-dehydrogenase isozyme 1, Short... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 45.5 kD |
ab 219,00 €