Zu "K15618" wurden 98 Artikel gefunden!
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Anti-BCL6
Artikelnummer: ABS-KC-1099.100
Protein function: Transcriptional repressor mainly required for germinal center (GC) formation and antibody affinity maturation which has different mechanisms of action specific to the lineage and biological functions. Forms complexes with different corepressors and histone deacetylases to repress the...
| Schlagworte: | Anti-B-cell lymphoma 6 protein, Anti-BCL-6, Anti-B-cell lymphoma 5 protein, Anti-BCL-5, Anti-Protein LAZ-3, Anti-Zinc... |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
ab 232,00 €
BI-3812
Artikelnummer: Cay41114-1
BI-3812 is an inhibitor of the oncogenic transcription factor Bcl-6 (IC50 = 95%. Formulation: (Request formulation change), A solid. Solubility: Acetonitrile: Slightly soluble: 0.1-1 mg/ml. SMILES: O=C1C(OCC(NC)=O)=CC2=C(N1C)C(OC)=CC(NC3=NC(N4CCC(CC4)C(N(C)C)=O)=NC=C3Cl)=C2. InChi Code:...
| Schlagworte: | 1-[5-chloro-4-[[1,2-dihydro-8-methoxy-1-methyl-3-[2-(methylamino)-2-oxoethoxy]-2-oxo-6-quinolinyl]amino]-2-pyrimidinyl]-N,... |
| Anwendung: | Bcl-6 inhibitor |
| CAS | 2166387-64-8 |
| MW: | 558 D |
ab 81,00 €
BI-3802
Artikelnummer: Cay41731-1
BI-3802 is a degrader of Bcl-6 with a half-maximal degradation concentration (DC50) value of 20 nM in SU-DHL-4 B cell lymphoma cells. It binds to Bcl-6 in a cell-free assay and inhibits the interaction of Bcl-6 with nuclear receptor co-repressor 1 (NCOR1) in a reporter assay (IC50s = =3 and 43 nM, respectively)....
| Schlagworte: | rel-2-[[6-[[5-chloro-2-[(3R,5S)-3,5-dimethyl-1-piperidinyl]-4-pyrimidinyl]amino]-1,2-dihydro-1-methyl-2-oxo-3-quinolinyl]o... |
| Anwendung: | Bcl-6 degrader |
| CAS | 2166387-65-9 |
| MW: | 485 D |
ab 103,00 €
BCL6 Protein, Human, Recombinant (His)
Artikelnummer: TGM-TMPH-00999-100ug
Description: BCL6 Protein, Human, Recombinant (His) is expressed in E. coli.
| Schlagworte: | Zinc finger protein 51, Zinc finger and BTB domain-containing protein 27, B-cell lymphoma 5 protein, BCL5, BCL-5, BCL-6,... |
| MW: | 84.8 kD |
ab 236,00 €
BCL6 Protein, Human, Recombinant
Artikelnummer: TGM-TMPH-01000-100ug
Description: BCL6 Protein, Human, Recombinant is expressed in E. coli.
| Schlagworte: | B-cell lymphoma 6 protein, BCL-6, BCL5, Zinc finger and BTB domain-containing protein 27, B-cell lymphoma 5 protein, BCL6,... |
| MW: | 79.0 kD |
ab 390,00 €
BCL6 Protein, Human, Recombinant (aa 1-150, His & Trx)
Artikelnummer: TGM-TMPY-02430-100ug
Description: The protein encoded by this gene is an evolutionarily conserved 95-kDa protein containing six C-terminal zinc-finger motifs and an N-terminal POZ domain. It has been reported that BCL-6 is present in DNA-binding complexes in nuclear extracts from various B-cell lines. There are many relationships...
| Schlagworte: | ZNF51, BCL5, B-cell CLL/lymphoma 6, LAZ3, ZBTB27, BCL6A |
| MW: | 34.2 kD |
397,00 €
CCT369260
Artikelnummer: Cay41314-10
CCT369260 is a degrader of Bcl-6. It induces degradation of Bcl-6 in SU-DHL-4, OCI-LY1, and Karpas-422 cells with half-maximal degradation concentration (DC50) values of 0.09, 0.049, and 0.062 µM, respectively. CCT369260 inhibits the growth of SU-DHL-4, OCI-LY1, and OCI-Ly3 cancer cells (GI50s = 0.092, 0.035, and...
| Schlagworte: | rel-5-[[5-chloro-2-[(3R,5S)-4,4-difluoro-3,5-dimethyl-1-piperidinyl]-4-pyrimidinyl]amino]-1,3-dihydro-3-(3-hydroxy-3-methy... |
| Anwendung: | Bcl-6 degrader |
| CAS | 2253878-44-1 |
| MW: | 509 D |
ab 267,00 €
TP-021
Artikelnummer: Cay41315-10
TP-021 is an inhibitor of the protein-protein interaction between Bcl-6 and Bcl-6 corepressor (BCoR). It inhibits the protein-protein interaction between the Bcl-6 BTB domain and BCoR in a mammalian two-hybrid assay (IC50 = 0.72 µM).Formal Name:...
| Schlagworte: | 6-[[2-chloro-4-nitro-5-[(tetrahydro-2H-pyran-4-yl)oxy]phenyl]amino]-3,4-dihydro-2(1H)-quinolinone |
| Anwendung: | Bcl-6-BCoR protein-protein interaction inhibitor |
| CAS | 2130878-25-8 |
| MW: | 417.8 D |
ab 267,00 €
BCL6-IN-8c
Artikelnummer: TGM-T14515-5mg
Description: BCL6-IN-8c is an orally active and potent inhibitor of B-cell lymphoma 6 (BCL6)-corepressor interaction(IC50 of 0.10 µM in cell-free enzyme-linked immunosorbent assay). Target: Others. Smiles: [O-][N+](=O)c1cc(Cl)c(Nc2ccc3NC(=O)CCc3c2)cc1OC1CCOCC1. References: Yasui T, et al. Discovery of a novel B-cell...
| Anwendung: | Bcl-6-BCoR protein-protein interaction inhibitor |
| CAS | 2130878-25-8 |
| MW: | 417.84 D |
970,00 €
B-cell lymphoma 6 protein (BCL6), human, recombinant
Artikelnummer: CSB-EP002625HU.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 1-706aa. Protein Length: Full Length. Tag Info: N-terminal GST-tagged. Target Protein Sequence: MASPADSCIQ FTRHASDVLL NLNRLRSRDI LTDVVIVVSR EQFRAHKTVL MACSGLFYSI FTDQLKCNLS VINLDPEINP EGFCILLDFM YTSRLNLREG NIMAVMATAM YLQMEHVVDT CRKFIKASEA EMVSAIKPPR...
| Schlagworte: | BCL5, BCL6, BCL-6, BCL-5, Protein LAZ-3, Zinc finger protein 51, B-cell lymphoma 6 protein, B-cell lymphoma 5 protein,... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 105.5 kD |
ab 247,00 €
B-cell lymphoma 6 protein (BCL6), partial, human,...
Artikelnummer: CSB-EP002625HU1.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 1-418aa. Protein Length: Partial. Tag Info: N-terminal 6xHis-SUMO-tagged. Target Protein Sequence: MASPADSCIQ FTRHASDVLL NLNRLRSRDI LTDVVIVVSR EQFRAHKTVL MACSGLFYSI FTDQLKCNLS VINLDPEINP EGFCILLDFM YTSRLNLREG NIMAVMATAM YLQMEHVVDT CRKFIKASEA...
| Schlagworte: | BCL5, BCL6, BCL-6, BCL-5, Protein LAZ-3, Zinc finger protein 51, B-cell lymphoma 6 protein, B-cell lymphoma 5 protein,... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 59.3 kD |
ab 247,00 €
B-cell lymphoma 6 protein (BCL6), human, recombinant
Artikelnummer: CSB-EP002625HUa0.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 1-706aa. Protein Length: Full Length. Tag Info: N-terminal 6xHis-tagged. Target Protein Sequence: MASPADSCIQ FTRHASDVLL NLNRLRSRDI LTDVVIVVSR EQFRAHKTVL MACSGLFYSI FTDQLKCNLS VINLDPEINP EGFCILLDFM YTSRLNLREG NIMAVMATAM YLQMEHVVDT CRKFIKASEA...
| Schlagworte: | BCL5, BCL6, BCL-6, BCL-5, Protein LAZ-3, Zinc finger protein 51, B-cell lymphoma 6 protein, B-cell lymphoma 5 protein,... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 84.8 kD |
ab 247,00 €