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Zu "K15601" wurden 59 Artikel gefunden!
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Artikelnummer: TGM-T9243-1mL
Description: PFI-90, a selective histone demethylase (KDM3B) inhibitor, targets PAX3-FOXO1 action and demonstrates potential antitumor activity. It induces apoptosis and myogenic differentiation, leading to increased cell death. Target: Histone Demethylase, Others. Smiles: O=C(NNc1ccccn1)c1ccccn1. References: KHAN,...
Anwendung: | KDM (lysine demethylase) inhibitor |
CAS | 53995-62-3 |
MW: | 214.22 D |
ab 34,00 €
Artikelnummer: TGM-TMPH-01622-100ug
Description: Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Demethylation of Lys residue generates formaldehyde and succinate. May have tumor suppressor activity.
Schlagworte: | JmjC domain-containing histone demethylation protein 2B, KDM3B, [histone H3]-dimethyl-L-lysine(9) demethylase 3B,... |
MW: | 45.6 kD |
ab 193,00 €
Artikelnummer: CSB-EP759174HU.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 1498-1721aa. Protein Length: Partial. Tag Info: N-terminal 10xHis-SUMO-tagged and C-terminal Myc-tagged. Target Protein Sequence: MPTRFEDLME NLPLPEYTKR DGRLNLASRL PSYFVRPDLG PKMYNAYGLI TAEDRRVGTT NLHLDVSDAV NVMVYVGIPI GEGAHDEEVL KTIDEGDADE VTKQRIHDGK...
Schlagworte: | KDM3B, C5orf7, Nuclear protein 5qNCA, Lysine-specific demethylase 3B, Jumonji domain-containing protein 1B, [histone... |
Anwendung: | Activity not tested |
Exprimiert in: | E.coli |
Ursprungsart: | human |
MW: | 45.6 kD |
ab 213,00 €
Artikelnummer: CSB-PA052445.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: KDM3B. Antigen Species: Human
Schlagworte: | Anti-KDM3B, Anti-C5orf7, Anti-Nuclear protein 5qNCA, Anti-Lysine-specific demethylase 3B, Anti-Jumonji domain-containing... |
Anwendung: | ELISA, WB, IHC |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse |
ab 163,00 €
Artikelnummer: CSB-PA980184.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: KDM3B. Antigen Species: Human
Schlagworte: | Anti-KDM3B, Anti-C5orf7, Anti-Nuclear protein 5qNCA, Anti-Lysine-specific demethylase 3B, Anti-Jumonji domain-containing... |
Anwendung: | ELISA, IHC |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse |
ab 163,00 €
Artikelnummer: Cay40120-100
PFI-90 is an inhibitor of lysine demethylases (KDMs). It inhibits KDM3B, KDM4B, KDM5A, and KDM6B by 46.8 to 87.1% when used at a concentration of 10 µM. PFI-90 induces cell death in SJSA-1 osteosarcoma and TC-32 Ewing's sarcoma cancer cells (IC50s = 2 and 1 µM, respectively).Formal Name: 2-(2-pyridinyl)hydrazide,...
Schlagworte: | 2-(2-pyridinyl)hydrazide, 2-pyridinecarboxylic acid |
Anwendung: | KDM (lysine demethylase) inhibitor |
CAS | 53995-62-3 |
MW: | 214.2 D |
ab 64,00 €
Artikelnummer: ELK-ELK0797.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human KDM3A. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human KDM3A. Next,...
Schlagworte: | KDM3A, JHDM2A, Lysine-specific demethylase 3A, Jumonji domain-containing protein 1A, [histone H3]-dimethyl-L-lysine(9)... |
Anwendung: | ELISA |
Spezies-Reaktivität: | human |
ab 365,00 €
Artikelnummer: A301-538A
Protein function: Histone demethylase that specifically demethylates 'Lys- 9' of histone H3, thereby playing a central role in histone code. Preferentially demethylates mono- and dimethylated H3 'Lys-9' residue, with a preference for dimethylated residue, while it has weak or no activity on trimethylated H3 'Lys-9'....
Schlagworte: | Anti-KDM3A, Anti-JHDM2A, EC=1.14.11.-, Anti-Lysine-specific demethylase 3A, Anti-Jumonji domain-containing protein 1A,... |
Anwendung: | WB, IP |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
ab 164,00 €
Artikelnummer: A301-539A
Protein function: Histone demethylase that specifically demethylates 'Lys- 9' of histone H3, thereby playing a central role in histone code. Preferentially demethylates mono- and dimethylated H3 'Lys-9' residue, with a preference for dimethylated residue, while it has weak or no activity on trimethylated H3 'Lys-9'....
Schlagworte: | Anti-KDM3A, Anti-JHDM2A, EC=1.14.11.-, Anti-Lysine-specific demethylase 3A, Anti-Jumonji domain-containing protein 1A,... |
Anwendung: | WB, IP |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
ab 164,00 €
Artikelnummer: BPS-50130
Human JMJD1A (also known as KDM3A or JHDM2A), GenBank Accession No. NM_018433, a.a. 2-1322 (end), with N-terminal FLAG-tag, MW=148.2 kDa, expressed in a Baculovirus infected Sf9 cell expression system.
Schlagworte: | KDM3A, JHDM2A, Lysine-specific demethylase 3A, Jumonji domain-containing protein 1A, [histone H3]-dimethyl-L-lysine(9)... |
Anwendung: | Enzyme kinetics, inhibitor screening, selectivity profiling |
Exprimiert in: | Baculovirus |
Ursprungsart: | human |
MW: | 148.2 kD |
686,00 €
Artikelnummer: BPS-50421
Human JMJD1B, also known as lysine-specific demethylase 3B (KDM3B), JHDM2B, and KIA1082, GenBank Accession No. NM_016604/ NP_057688, a.a. 2-1761 (end) with N-terminal Avi- and FLAG-tags, MW=195 kDa, expressed in a baculovirus-infected Sf9 cell expression system.
Schlagworte: | KDM3B, C5orf7, Nuclear protein 5qNCA, Lysine-specific demethylase 3B, Jumonji domain-containing protein 1B, [histone... |
Anwendung: | Enzyme kinetics, inhibitor screening, selectivity profiling |
Exprimiert in: | insect cells |
Ursprungsart: | human |
MW: | 195 kD |
686,00 €
Artikelnummer: A300-883A
Protein function: Histone demethylase that specifically demethylates 'Lys- 9' of histone H3, thereby playing a central role in histone code. Demethylation of Lys residue generates formaldehyde and succinate. May have tumor suppressor activity. [The UniProt Consortium]
Schlagworte: | Anti-KDM3B, Anti-C5orf7, EC=1.14.11.-, Anti-Nuclear protein 5qNCA, Anti-Lysine-specific demethylase 3B, Anti-Jumonji... |
Anwendung: | WB, IP, IHC |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
ab 164,00 €