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PFI-90
PFI-90

Artikelnummer: TGM-T9243-1mL

Description: PFI-90, a selective histone demethylase (KDM3B) inhibitor, targets PAX3-FOXO1 action and demonstrates potential antitumor activity. It induces apoptosis and myogenic differentiation, leading to increased cell death. Target: Histone Demethylase, Others. Smiles: O=C(NNc1ccccn1)c1ccccn1. References: KHAN,...
Anwendung: KDM (lysine demethylase) inhibitor
CAS 53995-62-3
MW: 214.22 D
ab 34,00 €
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KDM3B Protein, Human, Recombinant (His & Myc & SUMO)
KDM3B Protein, Human, Recombinant (His & Myc & SUMO)

Artikelnummer: TGM-TMPH-01622-100ug

Description: Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Demethylation of Lys residue generates formaldehyde and succinate. May have tumor suppressor activity.
Schlagworte: JmjC domain-containing histone demethylation protein 2B, KDM3B, [histone H3]-dimethyl-L-lysine(9) demethylase 3B,...
MW: 45.6 kD
ab 193,00 €
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Lysine-specific demethylase 3B (KDM3B), partial, human, recombinant
Lysine-specific demethylase 3B (KDM3B), partial, human,...

Artikelnummer: CSB-EP759174HU.1

Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 1498-1721aa. Protein Length: Partial. Tag Info: N-terminal 10xHis-SUMO-tagged and C-terminal Myc-tagged. Target Protein Sequence: MPTRFEDLME NLPLPEYTKR DGRLNLASRL PSYFVRPDLG PKMYNAYGLI TAEDRRVGTT NLHLDVSDAV NVMVYVGIPI GEGAHDEEVL KTIDEGDADE VTKQRIHDGK...
Schlagworte: KDM3B, C5orf7, Nuclear protein 5qNCA, Lysine-specific demethylase 3B, Jumonji domain-containing protein 1B, [histone...
Anwendung: Activity not tested
Exprimiert in: E.coli
Ursprungsart: human
MW: 45.6 kD
ab 213,00 €
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Anti-KDM3B
Anti-KDM3B

Artikelnummer: CSB-PA052445.100

Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: KDM3B. Antigen Species: Human
Schlagworte: Anti-KDM3B, Anti-C5orf7, Anti-Nuclear protein 5qNCA, Anti-Lysine-specific demethylase 3B, Anti-Jumonji domain-containing...
Anwendung: ELISA, WB, IHC
Wirt: Rabbit
Spezies-Reaktivität: human, mouse
ab 163,00 €
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Anti-KDM3B
Anti-KDM3B

Artikelnummer: CSB-PA980184.100

Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: KDM3B. Antigen Species: Human
Schlagworte: Anti-KDM3B, Anti-C5orf7, Anti-Nuclear protein 5qNCA, Anti-Lysine-specific demethylase 3B, Anti-Jumonji domain-containing...
Anwendung: ELISA, IHC
Wirt: Rabbit
Spezies-Reaktivität: human, mouse
ab 163,00 €
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PFI-90
PFI-90

Artikelnummer: Cay40120-100

PFI-90 is an inhibitor of lysine demethylases (KDMs). It inhibits KDM3B, KDM4B, KDM5A, and KDM6B by 46.8 to 87.1% when used at a concentration of 10 µM. PFI-90 induces cell death in SJSA-1 osteosarcoma and TC-32 Ewing's sarcoma cancer cells (IC50s = 2 and 1 µM, respectively).Formal Name: 2-(2-pyridinyl)hydrazide,...
Schlagworte: 2-(2-pyridinyl)hydrazide, 2-pyridinecarboxylic acid
Anwendung: KDM (lysine demethylase) inhibitor
CAS 53995-62-3
MW: 214.2 D
ab 64,00 €
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Human KDM3A (Lysine-specific demethylase 3A) ELISA Kit
Human KDM3A (Lysine-specific demethylase 3A) ELISA Kit

Artikelnummer: ELK-ELK0797.48

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human KDM3A. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human KDM3A. Next,...
Schlagworte: KDM3A, JHDM2A, Lysine-specific demethylase 3A, Jumonji domain-containing protein 1A, [histone H3]-dimethyl-L-lysine(9)...
Anwendung: ELISA
Spezies-Reaktivität: human
ab 365,00 €
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Anti-JMJD1A/JHDM2A
Anti-JMJD1A/JHDM2A

Artikelnummer: A301-538A

Protein function: Histone demethylase that specifically demethylates 'Lys- 9' of histone H3, thereby playing a central role in histone code. Preferentially demethylates mono- and dimethylated H3 'Lys-9' residue, with a preference for dimethylated residue, while it has weak or no activity on trimethylated H3 'Lys-9'....
Schlagworte: Anti-KDM3A, Anti-JHDM2A, EC=1.14.11.-, Anti-Lysine-specific demethylase 3A, Anti-Jumonji domain-containing protein 1A,...
Anwendung: WB, IP
Wirt: Rabbit
Spezies-Reaktivität: human
ab 164,00 €
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Anti-JMJD1A/JHDM2A
Anti-JMJD1A/JHDM2A

Artikelnummer: A301-539A

Protein function: Histone demethylase that specifically demethylates 'Lys- 9' of histone H3, thereby playing a central role in histone code. Preferentially demethylates mono- and dimethylated H3 'Lys-9' residue, with a preference for dimethylated residue, while it has weak or no activity on trimethylated H3 'Lys-9'....
Schlagworte: Anti-KDM3A, Anti-JHDM2A, EC=1.14.11.-, Anti-Lysine-specific demethylase 3A, Anti-Jumonji domain-containing protein 1A,...
Anwendung: WB, IP
Wirt: Rabbit
Spezies-Reaktivität: human
ab 164,00 €
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JMJD1A (KDM3A), human recombinant protein
JMJD1A (KDM3A), human recombinant protein

Artikelnummer: BPS-50130

Human JMJD1A (also known as KDM3A or JHDM2A), GenBank Accession No. NM_018433, a.a. 2-1322 (end), with N-terminal FLAG-tag, MW=148.2 kDa, expressed in a Baculovirus infected Sf9 cell expression system.
Schlagworte: KDM3A, JHDM2A, Lysine-specific demethylase 3A, Jumonji domain-containing protein 1A, [histone H3]-dimethyl-L-lysine(9)...
Anwendung: Enzyme kinetics, inhibitor screening, selectivity profiling
Exprimiert in: Baculovirus
Ursprungsart: human
MW: 148.2 kD
686,00 €
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JMJD1B (KDM3B), FLAG-tag
JMJD1B (KDM3B), FLAG-tag

Artikelnummer: BPS-50421

Human JMJD1B, also known as lysine-specific demethylase 3B (KDM3B), JHDM2B, and KIA1082, GenBank Accession No. NM_016604/ NP_057688, a.a. 2-1761 (end) with N-terminal Avi- and FLAG-tags, MW=195 kDa, expressed in a baculovirus-infected Sf9 cell expression system.
Schlagworte: KDM3B, C5orf7, Nuclear protein 5qNCA, Lysine-specific demethylase 3B, Jumonji domain-containing protein 1B, [histone...
Anwendung: Enzyme kinetics, inhibitor screening, selectivity profiling
Exprimiert in: insect cells
Ursprungsart: human
MW: 195 kD
686,00 €
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Anti-JMJD1B
Anti-JMJD1B

Artikelnummer: A300-883A

Protein function: Histone demethylase that specifically demethylates 'Lys- 9' of histone H3, thereby playing a central role in histone code. Demethylation of Lys residue generates formaldehyde and succinate. May have tumor suppressor activity. [The UniProt Consortium]
Schlagworte: Anti-KDM3B, Anti-C5orf7, EC=1.14.11.-, Anti-Nuclear protein 5qNCA, Anti-Lysine-specific demethylase 3B, Anti-Jumonji...
Anwendung: WB, IP, IHC
Wirt: Rabbit
Spezies-Reaktivität: human
ab 164,00 €
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