- Suchergebnis für K14963
Cookie-Einstellungen
Diese Website benutzt Cookies, die für den technischen Betrieb der Website erforderlich sind und stets gesetzt werden. Andere Cookies, die den Komfort bei Benutzung dieser Website erhöhen, der Direktwerbung dienen oder die Interaktion mit anderen Websites und sozialen Netzwerken vereinfachen sollen, werden nur mit Ihrer Zustimmung gesetzt.
Konfiguration
Technisch erforderlich
Diese Cookies sind für die Grundfunktionen des Shops notwendig.
"Alle Cookies ablehnen" Cookie
"Alle Cookies annehmen" Cookie
Ausgewählter Shop
CSRF-Token
Cookie-Einstellungen
FACT-Finder Tracking
Individuelle Preise
Kundenspezifisches Caching
Session
Währungswechsel
Komfortfunktionen
Diese Cookies werden genutzt um das Einkaufserlebnis noch ansprechender zu gestalten, beispielsweise für die Wiedererkennung des Besuchers.
Facebook-Seite in der rechten Blog - Sidebar anzeigen
Merkzettel
Statistik & Tracking
Endgeräteerkennung
Kauf- und Surfverhalten mit Google Tag Manager
Partnerprogramm
Zu "K14963" wurden 49 Artikel gefunden!
Filter schließen
Filtern nach:
Für die Filterung wurden keine Ergebnisse gefunden!
Artikelnummer: Cay41325-1
Homer is a proteolysis-targeting chimera (PROTAC) composed of the probe for WD repeat domain 5 (WDR5) OICR-9429 (Cay-16095) and a von Hippel-Lindau (VHL) ligand. It induces degradation of WDR5 in MV4-11 cells with a half-maximal degradation concentration (DC50) of 53 nM. Homer (1 µM) reduces WDR5 protein levels, but...
Schlagworte: | N-(4'-((5-(((S)-1-((2S,4R)-4-hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan... |
Anwendung: | WDR5 degradation driving PROTAC |
CAS | 2737222-94-3 |
MW: | 1012.2 D |
ab 66,00 €
Artikelnummer: CSB-EP026038HU.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 2-334aa. Protein Length: Full Length of Mature Protein. Tag Info: N-terminal 6xHis-SUMO-tagged. Target Protein Sequence: ATEEKKPETE AARAQPTPSS SATQSKPTPV KPNYALKFTL AGHTKAVSSV KFSPNGEWLA SSSADKLIKI WGAYDGKFEK TISGHKLGIS DVAWSSDSNL LVSASDDKTL...
Schlagworte: | BIG3, WDR5, BMP2-induced 3-kb gene protein, WD repeat-containing protein 5, Recombinant Human WD repeat-containing protein... |
Anwendung: | Activity not tested |
Exprimiert in: | E.coli |
Ursprungsart: | human |
MW: | 52.5 kD |
ab 213,00 €
Artikelnummer: CSB-PA062933.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: WDR5. Antigen Species: Human
Schlagworte: | Anti-BIG3, Anti-WDR5, Anti-WD repeat-containing protein 5, Anti-BMP2-induced 3-kb gene protein, 2410008O07Rik antibody,... |
Anwendung: | ELISA, WB, IHC |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse, rat |
ab 163,00 €
Artikelnummer: CSB-PA097823.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: WDR5. Antigen Species: Human
Schlagworte: | Anti-BIG3, Anti-WDR5, Anti-WD repeat-containing protein 5, Anti-BMP2-induced 3-kb gene protein, 2410008O07Rik antibody,... |
Anwendung: | ELISA, WB, IHC |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse, rat |
ab 163,00 €
Artikelnummer: CSB-RA620753A0HU.100
Isotype: Rabbit IgG. Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Affinity-chromatography. Target Name: WDR5. Antigen Species: Human
Schlagworte: | Anti-BIG3, Anti-WDR5, Anti-WD repeat-containing protein 5, Anti-BMP2-induced 3-kb gene protein, WD repeat-containing... |
Anwendung: | ELISA, IHC, FC |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
ab 201,00 €
Artikelnummer: A302-429A
Protein function: Contributes to histone modification. May position the N- terminus of histone H3 for efficient trimethylation at 'Lys-4'. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic...
Schlagworte: | Anti-WDR5, Anti-BIG3, Anti-BMP2-induced 3-kb gene protein, Anti-WD repeat-containing protein 5 |
Anwendung: | WB, IP, IHC |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
ab 164,00 €
Artikelnummer: Cay17699-1
WD-repeat protein 5 (WDR5) is a scaffold protein commonly involved in the formation of nucleosome-modifying protein complexes with histones. It serves as a component of a mixed-lineage leukemia (MLL) methyltransferase complex that targets histone 3 at lysine 4 to upregulate transcription. MM-102 is a potent WDR5/MLL...
Schlagworte: | 1-[[(2S)-5-[(aminoiminomethyl)amino]-2-[[2-ethyl-2-[(2-methyl-1-oxopropyl)amino]-1-oxobutyl]amino]-1-oxopentyl]amino]-N-[b... |
Anwendung: | WDR5/MLL interaction inhibitor |
CAS | 1417329-24-8 |
MW: | 669.8 D |
ab 43,00 €
Artikelnummer: A302-430A
Protein function: Contributes to histone modification. May position the N- terminus of histone H3 for efficient trimethylation at 'Lys-4'. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic...
Schlagworte: | Anti-WDR5, Anti-BIG3, Anti-BMP2-induced 3-kb gene protein, Anti-WD repeat-containing protein 5 |
Anwendung: | WB, IP, IHC |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse, rat |
ab 164,00 €
Artikelnummer: Cay16095-1
WD-repeat protein 5 (WDR5) is a scaffold protein commonly involved in the formation of nucleosome-modifying protein complexes with histones. For example, WDR5 is a component of a mixed-lineage leukemia (MLL) methyltransferase complex that targets histone 3. WDR5 can also be a component of histone acetyltransferase...
Schlagworte: | N-(4-(4-methylpiperazin-1-yl)-3'-(morpholinomethyl)-[1,1'-biphenyl]-3-yl)-6-oxo-4-(trifluoromethyl)-1,6-dihydropyridine-3-... |
Anwendung: | WDR5 binding inhibitor |
CAS | 1801787-56-3 |
MW: | 555.6 D |
ab 77,00 €
Artikelnummer: BPS-71200
Human WDR5 (WD Repeat Domain 5), also known as SWD3 or BIG-3, GenBank Accession No. NM_017588, amino acids 2-334(end), with N-terminal His-tag, MW=37.5 kDa, expressed in Sf9 insect cells via a baculovirus expression system.
Schlagworte: | WDR5, BIG3, BMP2-induced 3-kb gene protein, WD repeat-containing protein 5, |
Anwendung: | Enzyme kinetics, inhibitor screening, selectivity profiling |
Exprimiert in: | Baculovirus |
Ursprungsart: | human |
MW: | 37.5 kD |
679,00 €
Artikelnummer: Cay10944-100
WD repeats are motifs of approximately 40 amino acids typically terminating in conserved tryptophan and aspartate residues. Several WD40 repeats combine to form the structural WD domain. Such an arrangement facilitates protein-protein interactions allowing the formation of multiprotein complexes. Human WDR5 contains...
Schlagworte: | BIG3, BMP2-induced 3-kb Gene Protein, SWD3, Set1c WD40 repeat protein, homolog, WD-Repeat Protein 5 |
Anwendung: | Enzyme activity |
Exprimiert in: | E.coli |
MW: | 34,4 kD |
500,00 €
Artikelnummer: Cay13945-1
WD-repeat protein 5 (WDR5) is a scaffold protein commonly involved in the formation of nucleosome-modifying protein complexes with histones. For example, WDR5 is a component of a mixed-lineage leukemia (MLL) methyltransferase complex that targets histone 3. WDR5 can also be a component of histone acetyltransferase...
Schlagworte: | WD-Repeat Protein 5-0103, 3-[(3-methoxybenzoyl)amino]-4-(4-methyl-1-piperazinyl)-benzoic acid, methyl ester |
Anwendung: | MLL core complex inhibitor |
CAS | 890190-22-4 |
MW: | 383.4 D |
ab 34,00 €