Zu "K14963" wurden 62 Artikel gefunden!
Für die Filterung wurden keine Ergebnisse gefunden!
Anti-WDR5
Artikelnummer: ATA-HPA076612.100
Polyclonal Antibody against Human WDR5, Gene description: WD repeat domain 5, Alternative Gene Names: CFAP89, SWD3, Validated applications: ICC, Uniprot ID: P61964, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C. Protein function: Contributes to histone modification...
| Schlagworte: | Anti-WDR5, Anti-BIG3, Anti-BMP2-induced 3-kb gene protein, Anti-WD repeat-containing protein 5 |
| Anwendung: | ICC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
450,00 €
OICR-9429
Artikelnummer: TGM-T6916-100mg
Description: OICR-9429 is a potent antagonist of the interaction that WDR5 effect with peptide regions of MLL and Histone 3. It reduces the viability of acute myeloid leukemia cells in vitro. Target: Histone Methyltransferase, JAK. Smiles: CN1CCN(CC1)c1ccc(cc1NC(=O)c1c[nH]c(=O)cc1C(F)(F)F)-c1cccc(CN2CCOCC2)c1....
| Schlagworte: | OICR 9429 |
| Anwendung: | WDR5 binding inhibitor |
| CAS | 1801787-56-3 |
| MW: | 555.59 D |
ab 31,00 €
WDR5 Protein, Human, Recombinant (His & SUMO)
Artikelnummer: TGM-TMPH-02311-100ug
Description: WDR5 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 52.5 kDa and the accession number is P61964.
| Schlagworte: | BMP2-induced 3-kb gene protein, WD repeat-containing protein 5, WDR5 |
| MW: | 52.5 kD |
ab 198,00 €
MM-102
Artikelnummer: TGM-T6333-100mg
Description: MM-102 (HMTase Inhibitor IX) is a high-affinity peptidomimetic MLL1 inhibitor with an IC50 of 0.4 µM. Target: Histone Methyltransferase. Smiles: C(NC(C1=CC=C(F)C=C1)C2=CC=C(F)C=C2)(=O)C3(NC([C@@H](NC(C(NC(C(C)C)=O)(CC)CC)=O)CCCNC(=N)N)=O)CCCC3. References: Karatas H, et al. J Am Chem Soc. 2013, 135(2),...
| Schlagworte: | MM102, HMTase Inhibitor IX |
| Anwendung: | WDR5/MLL interaction inhibitor |
| CAS | 1417329-24-8 |
| MW: | 669.8 D |
ab 34,00 €
WDR5-MYC Probe 12
Artikelnummer: Cay39304-1
WDR5-MYC probe 12 is an inhibitor of the protein-protein interaction between the master transcription factor Myc and WD repeat domain 5 (WDR5, IC50 = 0.39 µM). It reduces mRNA expression of the Myc and WDR5 co-binding target genes ribosomal protein L17 (RPL17), RPL23, RPL35, and RPL37A in HL-60 cells. WDR5-MYC probe...
| Schlagworte: | 3',5'-difluoro-4'-((6-methyl-4-oxo-1-phenyl-1,4-dihydropyridazine-3-carboxamido)methyl)-[1,1'-biphenyl]-3-sulfonyl fluoride |
| Anwendung: | Myc-WDR5 protein-protein interaction inhibitor |
| MW: | 513.5 D |
ab 90,00 €
Homer
Artikelnummer: Cay41325-1
Homer is a proteolysis-targeting chimera (PROTAC) composed of the probe for WD repeat domain 5 (WDR5) OICR-9429 (Cay-16095) and a von Hippel-Lindau (VHL) ligand. It induces degradation of WDR5 in MV4-11 cells with a half-maximal degradation concentration (DC50) of 53 nM. Homer (1 µM) reduces WDR5 protein levels, but...
| Schlagworte: | N-(4'-((5-(((S)-1-((2S,4R)-4-hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan... |
| Anwendung: | WDR5 degradation driving PROTAC |
| CAS | 2737222-94-3 |
| MW: | 1012.2 D |
ab 67,00 €
WD repeat-containing protein 5 (WDR5), human, recombinant
Artikelnummer: CSB-EP026038HU.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 2-334aa. Protein Length: Full Length of Mature Protein. Tag Info: N-terminal 6xHis-SUMO-tagged. Target Protein Sequence: ATEEKKPETE AARAQPTPSS SATQSKPTPV KPNYALKFTL AGHTKAVSSV KFSPNGEWLA SSSADKLIKI WGAYDGKFEK TISGHKLGIS DVAWSSDSNL LVSASDDKTL...
| Schlagworte: | BIG3, WDR5, BMP2-induced 3-kb gene protein, WD repeat-containing protein 5, Recombinant Human WD repeat-containing protein... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 52.5 kD |
ab 219,00 €
Anti-WDR5
Artikelnummer: CSB-PA062933.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: WDR5. Antigen Species: Human
| Schlagworte: | Anti-BIG3, Anti-WDR5, Anti-WD repeat-containing protein 5, Anti-BMP2-induced 3-kb gene protein, 2410008O07Rik antibody,... |
| Anwendung: | ELISA, WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 167,00 €
Anti-WDR5
Artikelnummer: CSB-PA097823.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: WDR5. Antigen Species: Human
| Schlagworte: | Anti-BIG3, Anti-WDR5, Anti-WD repeat-containing protein 5, Anti-BMP2-induced 3-kb gene protein, 2410008O07Rik antibody,... |
| Anwendung: | ELISA, WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 167,00 €
Anti-WDR5
Artikelnummer: A302-429A
Protein function: Contributes to histone modification. May position the N- terminus of histone H3 for efficient trimethylation at 'Lys-4'. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic...
| Schlagworte: | Anti-WDR5, Anti-BIG3, Anti-BMP2-induced 3-kb gene protein, Anti-WD repeat-containing protein 5 |
| Anwendung: | WB, IP, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 178,00 €
MM-102
Artikelnummer: Cay17699-1
WD-repeat protein 5 (WDR5) is a scaffold protein commonly involved in the formation of nucleosome-modifying protein complexes with histones. It serves as a component of a mixed-lineage leukemia (MLL) methyltransferase complex that targets histone 3 at lysine 4 to upregulate transcription. MM-102 is a potent WDR5/MLL...
| Schlagworte: | 1-[[(2S)-5-[(aminoiminomethyl)amino]-2-[[2-ethyl-2-[(2-methyl-1-oxopropyl)amino]-1-oxobutyl]amino]-1-oxopentyl]amino]-N-[b... |
| Anwendung: | WDR5/MLL interaction inhibitor |
| CAS | 1417329-24-8 |
| MW: | 669.8 D |
ab 44,00 €
Anti-WDR5
Artikelnummer: A302-430A
Protein function: Contributes to histone modification. May position the N- terminus of histone H3 for efficient trimethylation at 'Lys-4'. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic...
| Schlagworte: | Anti-WDR5, Anti-BIG3, Anti-BMP2-induced 3-kb gene protein, Anti-WD repeat-containing protein 5 |
| Anwendung: | WB, IP, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 178,00 €