Zu "K14381" wurden 73 Artikel gefunden!
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PTX80
Artikelnummer: Cay41676-1
PTX80 is an antagonist of p62 (IC50 = 31.18 nM for the human receptor). It decreases the soluble fraction of p62 in MM.1S multiple myeloma cells when used at a concentration of 1.5 µM. PTX80 (200 nM) increases the levels of polyubiquitinated proteins in MM.1S cells. It induces apoptosis in MM.1S cells when used at a...
| Schlagworte: | 4,4'-((1E,1'E)-(1-((3-(dimethylamino)propyl)sulfonyl)-4-oxopiperidine-3,5-diylidene)bis(methaneylylidene))dibenzonitrile |
| Anwendung: | p62 (SQSTM1) antagonist |
| CAS | 2376297-69-5 |
| MW: | 474.6 D |
ab 40,00 €
XIE62-1004
Artikelnummer: TGM-T83945-10mg
Description: XIE62-1004 is a chemical compound that induces the interaction between p62 and LC3 by binding to the ZZ domain of p62. This interaction promotes p62 self-aggregation and its subsequent interaction with LC3 on autophagosome membranes, thereby facilitating the delivery of cargo proteins to the...
| Anwendung: | Autophagy inducer |
| CAS | 2421146-32-7 |
| MW: | 399.91 D |
ab 419,00 €
XIE62-1004
Artikelnummer: Cay40446-1
XIE62-1004 is an inducer of autophagy. It increases the number of p62 aggregates, as well as the number of autophagosomes and autolysosomes, in wild-type HeLa cervical cancer cells, but not in HeLa cells deficient in the gene encoding p62, SQSTM1, when used at a concentration of 10 µM. XIE62-1004 induces autophagic...
| Schlagworte: | 2-[[[3,4-bis(phenylmethoxy)phenyl]methyl]amino]-ethanol, monohydrochloride |
| Anwendung: | Autophagy inducer |
| CAS | 2421146-32-7 |
| MW: | 399.9 D |
ab 39,00 €
Anti-p62 / SQSTM1, clone 3H11
Artikelnummer: NSJ-RQ5514
0.5mg/ml if reconstituted with 0.2ml sterile DI water. SQSTM1 (Sequestosome-1), also known as Ubiquitin-Binding Protein P62 or P62, is a protein that in humans is encoded by the SQSTM1 gene. The Src homology type 2 (SH2) domain is a highly conserved motif of about 100 amino acids which mediates protein-protein...
| Schlagworte: | Anti-p60, Anti-ORCA, Anti-EBIAP, Anti-SQSTM1, Anti-Sequestosome-1, Anti-Ubiquitin-binding protein p62,... |
| Anwendung: | WB, IHC (paraffin), IF, FC |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human, mouse, rat |
755,00 €
Anti-Sequestosome-1
Artikelnummer: A302-856A
Protein function: Autophagy receptor that interacts directly with both the cargo to become degraded and an autophagy modifier of the MAP1 LC3 family. Required both for the formation and autophagic degradation of polyubiquitin-containing bodies, called ALIS (aggresome-like induced structures) and links ALIS to the...
| Schlagworte: | Anti-p60, Anti-ORCA, Anti-EBIAP, Anti-SQSTM1, Anti-Sequestosome-1, Anti-Ubiquitin-binding protein p62,... |
| Anwendung: | WB, IP, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 164,00 €
Anti-p62
Artikelnummer: NSJ-R31058
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Sequestosome-1, also known as Ubiquitin-Binding Protein p62, is a protein that in humans is encoded by the SQSTM1 gene. The Src homology type 2(SH2) domain is a highly conserved motif of about 100 amino acids which mediates protein-protein interactions by...
| Schlagworte: | Anti-p60, Anti-ORCA, Anti-EBIAP, Anti-SQSTM1, Anti-Sequestosome-1, Anti-Ubiquitin-binding protein p62,... |
| Anwendung: | WB, IHC (paraffin), ICC, IF, FC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
755,00 €
-30 %
Rabattaktion
Anti-SQSTM1 / p62
Artikelnummer: ARG55040.100
Protein function: Autophagy receptor required for selective macroautophagy (aggrephagy). Functions as a bridge between polyubiquitinated cargo and autophagosomes. Interacts directly with both the cargo to become degraded and an autophagy modifier of the MAP1 LC3 family (PubMed:16286508, PubMed:20168092,...
| Schlagworte: | Anti-p60, Anti-ORCA, Anti-EBIAP, Anti-SQSTM1, Anti-Sequestosome-1, Anti-Ubiquitin-binding protein p62,... |
| Anwendung: | WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
436,00 €
ab 305,20 €
-30 %
Rabattaktion
Anti-SQSTM1 / p62
Artikelnummer: ARG57285.50
Protein function: Autophagy receptor that interacts directly with both the cargo to become degraded and an autophagy modifier of the MAP1 LC3 family. Required both for the formation and autophagic degradation of polyubiquitin-containing bodies, called ALIS (aggresome-like induced structures) and links ALIS to the...
| Schlagworte: | Anti-p60, Anti-ORCA, Anti-EBIAP, Anti-SQSTM1, Anti-Sequestosome-1, Anti-Ubiquitin-binding protein p62,... |
| Anwendung: | ICC, IF, IHC (paraffin), WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, rat |
520,00 €
364,00 €
-30 %
Rabattaktion
Anti-SQSTM1 / p62
Artikelnummer: ARG57395.100
Protein function: Autophagy receptor that interacts directly with both the cargo to become degraded and an autophagy modifier of the MAP1 LC3 family (PubMed:16286508, PubMed:20168092, PubMed:24128730). Required both for the formation and autophagic degradation of polyubiquitin-containing bodies, called ALIS...
| Schlagworte: | Anti-p60, Anti-ORCA, Anti-EBIAP, Anti-SQSTM1, Anti-Sequestosome-1, Anti-Ubiquitin-binding protein p62,... |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
624,00 €
436,80 €
Anti-Sequestosome-1
Artikelnummer: A302-855A
Protein function: Autophagy receptor that interacts directly with both the cargo to become degraded and an autophagy modifier of the MAP1 LC3 family. Required both for the formation and autophagic degradation of polyubiquitin-containing bodies, called ALIS (aggresome-like induced structures) and links ALIS to the...
| Schlagworte: | Anti-p60, Anti-ORCA, Anti-EBIAP, Anti-SQSTM1, Anti-Sequestosome-1, Anti-Ubiquitin-binding protein p62,... |
| Anwendung: | WB, IP, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 164,00 €
Anti-Sequestosome-1
Artikelnummer: A302-857A
Protein function: Autophagy receptor that interacts directly with both the cargo to become degraded and an autophagy modifier of the MAP1 LC3 family. Required both for the formation and autophagic degradation of polyubiquitin-containing bodies, called ALIS (aggresome-like induced structures) and links ALIS to the...
| Schlagworte: | Anti-p60, Anti-ORCA, Anti-EBIAP, Anti-SQSTM1, Anti-Sequestosome-1, Anti-Ubiquitin-binding protein p62,... |
| Anwendung: | WB, IP, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 164,00 €
Anti-SREBF2
Artikelnummer: 600-401-EU9
Anti-SREBF2 antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. SREBF2 antibody is human and mouse reactive. At least three isoforms of SREBF2 are known to exist. SREBF2 antibody is predicted not to cross-react with SREBF1. Protein function: Autophagy receptor that interacts...
| Schlagworte: | Anti-p60, Anti-ORCA, Anti-EBIAP, Anti-SQSTM1, Anti-Sequestosome-1, Anti-Ubiquitin-binding protein p62,... |
| Anwendung: | ELISA, IHC, IFM, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
684,00 €