Zu "K14342" wurden 27 Artikel gefunden!
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Elobixibat
Artikelnummer: TGM-T15209-100mg
Description: Elobixibat (A 3309) is an inhibitor of the ileal bile acid transporter (IC50: 0.13 nM, 0.53 nM, and 5.8 nM for mouse, human, and canine IBAT). Elobixibat can be used in studies about chronic idiopathic constipation. Target: Others. Smiles:...
| Schlagworte: | AZD 7806, A 3309 |
| Anwendung: | Targets solute carrier family 10 (sodium/bile acid cotransporter), member 2 (SLC10A2, ASBT) |
| CAS | 439087-18-0 |
| MW: | 695.89 D |
ab 263,00 €
Odevixibat
Artikelnummer: TGM-T16376-100mg
Description: Odevixibat (A4250) is an effective, selective and orally active ileal bile acid transporter inhibitor. Odevixibat has the potential for the treatment of primary biliary cirrhosis. Odevixibat reduces cholestatic liver and bile duct injury in mice model. Target: Others. Smiles:...
| Schlagworte: | A4250 |
| Anwendung: | Targets solute carrier family 10 (sodium/bile acid cotransporter), member 2 (SLC10A2, ASBT) |
| CAS | 501692-44-0 |
| MW: | 740.93 D |
ab 54,00 €
Maralixibat Chloride
Artikelnummer: TGM-T32873-100mg
Description: Maralixibat Chloride (LUM001 chloride), an apical, sodium-dependent, bile acid transport inhibitor, prevents enterohepatic bile acid recirculation. Target: Potassium Channel. Smiles: [Cl-].CCCCC1(CCCC)CS(=O)(=O)c2ccc(cc2[C@H]([C@H]1O)c1ccc(OCc2ccc(C[N+]34CCN(CC3)CC4)cc2)cc1)N(C)C. References: Kurata,...
| Schlagworte: | SHP-625, SHP625, Livmarli, LUM001 chloride, Lopixibat chloride, Lopixibat, SHP 625, SHP625 chloride |
| Anwendung: | Targets solute carrier family 10 (sodium/bile acid cotransporter), member 2 (SLC10A2, ASBT) |
| CAS | 228113-66-4 |
| MW: | 710.41 D |
ab 262,00 €
Ganglioside GM1 Mixture (ovine) (ammonium salt)
Artikelnummer: TGM-T37582-1mg
Description: Ganglioside GM1is a monosialylated ganglioside and the prototypic ganglioside for those containing one sialic acid residue.1,2It is found in a large variety of cells, including immune cells and neurons, and is enriched in lipid rafts in the cell membrane.3It associates with growth factor receptors,...
| Anwendung: | Monosialylated gangliosides |
| CAS | 1007119-81-4 |
| MW: | 1563.9 D |
ab 303,00 €
Linerixibat
Artikelnummer: TGM-T3978-10mg
Description: Linerixibat (GSK2330672) is a highly effective, nonabsorbable ASBT inhibitor (IC50: 42 ± 3 nM) that can lower glucose in an animal model of type 2 diabetes and demonstrates excellent developability properties. Target: HBV. Smiles:...
| Schlagworte: | Iinerixibat, GSK2330672 |
| Anwendung: | Targets solute carrier family 10 (sodium/bile acid cotransporter), member 2 (SLC10A2, ASBT) |
| CAS | 1345982-69-5 |
| MW: | 546.68 D |
ab 76,00 €
Anti-SLC10A2
Artikelnummer: CSB-PA843819.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-IBAT, Anti-ISBT, Anti-ASBT, Anti-SLC10A2, Anti-Solute carrier family 10 member 2, Anti-Ileal Na(+)/bile acid... |
| Anwendung: | ELISA, WB, |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 167,00 €
Elobixibat
Artikelnummer: Cay30658-1
Elobixibat is an inhibitor of the sodium/bile acid and sulfated solute cotransporter (ASBT), also known as the ileal bile acid transporter (IBAT, IC50s = 0.53, 0.13, and 5.8 nM for the human, mouse, and canine transporters, respectively). It is selective for ASBT over the hepatic sodium/bile acid cotransporter (IC50...
| Schlagworte: | A3309, AZD 7806,... |
| Anwendung: | ASBT inhibitor |
| CAS | 439087-18-0 |
| MW: | 695.9 D |
ab 136,00 €
Ganglioside GM1 (bovine) (ammonium salt)
Artikelnummer: Cay31548-1
Ganglioside GM1 is a monosialylated ganglioside and the prototypic ganglioside for those containing one sialic acid residue. It is found in a large variety of cells, including immune cells and neurons, and is enriched in lipid rafts in the cell membrane. It associates with growth factor receptors, including TrkA,...
| Schlagworte: | GM1, Monosialoganglioside GM1,... |
| Anwendung: | Monosialylated gangliosides |
| CAS | 1007119-81-4 |
| MW: | 1563.9 D |
163,00 €
Rat SLC10A2 (Ileal Sodium/Bile Acid Cotransporter) ELISA Kit
Artikelnummer: ELK-ELK0437.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat SLC10A2. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat SLC10A2. Next,...
| Schlagworte: | IBAT, ISBT, ASBT, Ntcp2, Slc10a2, Solute carrier family 10 member 2, Ileal Na(+)/bile acid cotransporter, Ileal... |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | rat |
ab 374,00 €
Anti-Slc10a2, C-terminal
Artikelnummer: ARG64665.100
Protein function: Plays a critical role in the sodium-dependent reabsorption of bile acids from the lumen of the small intestine. Plays a key role in cholesterol metabolism. [The UniProt Consortium]
| Schlagworte: | Anti-ISBT, Anti-IBAT, Anti-ASBT, Anti-Ntcp2, Anti-Slc10a2, Anti-Solute carrier family 10 member 2, Anti-Ileal Na(+)/bile... |
| Anwendung: | ELISA, WB |
| Wirt: | Goat |
| Spezies-Reaktivität: | mouse |
822,00 €
Anti-SLC10A2 / ASBT, C-terminal
Artikelnummer: ARG64875.100
Protein function: Plays a critical role in the sodium-dependent reabsorption of bile acids from the lumen of the small intestine. Plays a key role in cholesterol metabolism. [The UniProt Consortium]
| Schlagworte: | Anti-ISBT, Anti-IBAT, Anti-ASBT, Anti-SLC10A2, Anti-Solute carrier family 10 member 2, Anti-Ileal Na(+)/bile acid... |
| Anwendung: | ELISA, IHC (paraffin) |
| Wirt: | Goat |
| Spezies-Reaktivität: | human |
822,00 €
Anti-Slc10a2
Artikelnummer: NSJ-R33430-100UG
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Solute carrier family 10 (sodium/bile acid cotransporter family), member 2 Protein function: Plays a critical role in the sodium-dependent reabsorption of bile acids from the lumen of the small...
| Schlagworte: | Anti-IBAT, Anti-ASBT, Anti-ISBT, Anti-Ntcp2, Anti-Slc10a2, Anti-Solute carrier family 10 member 2, Anti-Ileal Na(+)/bile... |
| Anwendung: | WB, ELISA (peptide) |
| Wirt: | Goat |
| Spezies-Reaktivität: | mouse |
790,00 €