Zu "K14163" wurden 28 Artikel gefunden!
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Halofuginone hydrobromide
Artikelnummer: TGM-T3524-100mg
Description: Halofuginone specifically inhibits collagen type I gene expression and matrix metalloproteinase 2 (MMP-2) gene expression, which may result in the suppression of angiogenesis, tumor stromal cell development, and tumor cell growth. Halofuginone Hydrobromide is the hydrobromide salt of halofuginone, a...
| Schlagworte: | Stenorol, Tempostatin, RU-19110 (hydrobromide) |
| Anwendung: | Targets bifunctional glutamyl/prolyl-tRNA synthetase [EC:6.1.1.17 6.1.1.15] (EPRS) |
| CAS | 64924-67-0 |
| MW: | 495.59 D |
ab 31,00 €
Bersiporocin
Artikelnummer: TGM-T39739-5mg
Description: Bersiporocin, a prolyl-tRNA synthetase inhibitor, demonstrates potent activity with an IC50 of =100 nM against phosphoribosylpyrophosphate synthetase (PRS). This compound proves valuable for antifibrotic research. Target: Others. Smiles: O[C@H]1CCCN[C@@H]1CCCn1cnc2c(Cl)c(Cl)ccc12. References: Bong-Yong...
| Anwendung: | Targets bifunctional glutamyl/prolyl-tRNA synthetase [EC:6.1.1.17 6.1.1.15] (EPRS) |
| CAS | 2241808-52-4 |
| MW: | 328.24 D |
ab 4.164,00 €
Halofuginone
Artikelnummer: TGM-T6856-100mg
Description: Halofuginone (RU-19110), the competitive inhibitor of prolyl-tRNA synthetase(Ki=18.3 nM), could also down-regulate Smad3 and blocked TGF-beta signaling at 10 ng/ml in the mammal. Target: Parasite, DNA/RNA Synthesis, Sodium Channel, Calcium Channel, TGF-beta/Smad. Smiles:...
| Schlagworte: | Tempostatin, RU-19110, empostatin |
| Anwendung: | Targets bifunctional glutamyl/prolyl-tRNA synthetase [EC:6.1.1.17 6.1.1.15] (EPRS) |
| CAS | 55837-20-2 |
| MW: | 414.68 D |
ab 31,00 €
Halofuginone (hydrochloride)
Artikelnummer: Cay13370-500
Halofuginone is a halogenated derivative of febrifugine, a natural quinazolinone-containing compound found in the Chinese herb D. febrifuga. It has antimalarial and anticoccidial actions. In mammals, halofuginone at 10 ng/ml down-regulates Smad3, blocking TGF-beta signaling and preventing both the differentiation of...
| Schlagworte: | 7-bromo-6-chloro-3-[3-[(2R,3S)-3-hydroxy-2-piperidinyl]-2-oxopropyl]-4(3H)-quinazolinone, monohydrochloride |
| Anwendung: | Antiprotozoal, glutamyl-prolyl-tRNA synthetase (EPRS) inhibitor, Smad3 down-regulator |
| CAS | 1217623-74-9 |
| MW: | 451.1 D |
ab 166,00 €
Anti-EPRS
Artikelnummer: A303-958A-T
Protein function: Catalyzes the attachment of the cognate amino acid to the corresponding tRNA in a two-step reaction: the amino acid is first activated by ATP to form a covalent intermediate with AMP and is then transferred to the acceptor end of the cognate tRNA (PubMed:1756734, PubMed:24100331, PubMed:23263184)....
| Schlagworte: | Anti-EPRS, Anti-GLNS, Anti-GluRS, Anti-PIG32, EC=6.1.1.17, Anti-Proline--tRNA ligase, Anti-Prolyl-tRNA synthetase,... |
| Anwendung: | WB, IP, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 178,00 €
Anti-EPRS
Artikelnummer: A303-957A
Protein function: Catalyzes the attachment of the cognate amino acid to the corresponding tRNA in a two-step reaction: the amino acid is first activated by ATP to form a covalent intermediate with AMP and is then transferred to the acceptor end of the cognate tRNA (PubMed:1756734, PubMed:24100331, PubMed:23263184)....
| Schlagworte: | Anti-EPRS, Anti-GLNS, Anti-GluRS, Anti-PIG32, EC=6.1.1.17, Anti-Proline--tRNA ligase, Anti-Prolyl-tRNA synthetase,... |
| Anwendung: | WB, IP, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 178,00 €
Anti-EPRS
Artikelnummer: A303-959A
Protein function: Catalyzes the attachment of the cognate amino acid to the corresponding tRNA in a two-step reaction: the amino acid is first activated by ATP to form a covalent intermediate with AMP and is then transferred to the acceptor end of the cognate tRNA (PubMed:1756734, PubMed:24100331, PubMed:23263184)....
| Schlagworte: | Anti-EPRS, Anti-GLNS, Anti-GluRS, Anti-PIG32, EC=6.1.1.17, Anti-Proline--tRNA ligase, Anti-Prolyl-tRNA synthetase,... |
| Anwendung: | WB, IP, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 178,00 €
Anti-EPRS
Artikelnummer: E-AB-18006.120
Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. The protein encoded by this gene is a multifunctional aminoacyl-tRNA synthetase that catalyzes the aminoacylation of glutamic acid and proline tRNA species. Alternative splicing has been observed for this gene, but...
| Schlagworte: | Anti-EPRS, Anti-GLNS, Anti-GluRS, Anti-PIG32, EC=6.1.1.17, Anti-Proline--tRNA ligase, Anti-Glutamate--tRNA ligase,... |
| Anwendung: | IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 89,00 €
Anti-EPRS
Artikelnummer: ATA-HPA026490.100
Protein function: Multifunctional protein which is primarily part of the aminoacyl-tRNA synthetase multienzyme complex, also know as multisynthetase complex, that catalyzes the attachment of the cognate amino acid to the corresponding tRNA in a two-step reaction: the amino acid is first activated by ATP to form a...
| Schlagworte: | Anti-EPRS, Anti-GluRS, Anti-PIG32, EC=6.1.1.17, Anti-Proline--tRNA ligase, Anti-Glutamate--tRNA ligase, Anti-Prolyl-tRNA... |
| Anwendung: | WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 358,00 €
Anti-EPRS
Artikelnummer: ATA-HPA030052.100
Protein function: Multifunctional protein which is primarily part of the aminoacyl-tRNA synthetase multienzyme complex, also know as multisynthetase complex, that catalyzes the attachment of the cognate amino acid to the corresponding tRNA in a two-step reaction: the amino acid is first activated by ATP to form a...
| Schlagworte: | Anti-EPRS, Anti-GluRS, Anti-PIG32, EC=6.1.1.17, Anti-Proline--tRNA ligase, Anti-Glutamate--tRNA ligase, Anti-Prolyl-tRNA... |
| Anwendung: | WB, IHC, ICC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 239,00 €
Anti-EPRS / Proline--tRNA ligase
Artikelnummer: NSJ-RQ6380
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Bifunctional aminoacyl-tRNA synthetase is an enzyme that in humans is encoded by the EPRS1 gene. Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. The protein encoded by this gene is a multifunctional...
| Schlagworte: | Anti-EPRS, Anti-GluRS, Anti-PIG32, EC=6.1.1.17, Anti-Proline--tRNA ligase, Anti-Prolyl-tRNA synthetase,... |
| Anwendung: | WB, IHC (paraffin), IF, FC, Direct ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
772,00 €
Anti-EPRS1 / Proline--tRNA ligase
Artikelnummer: NSJ-RQ6742
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Bifunctional aminoacyl-tRNA synthetase is an enzyme that in humans is encoded by the EPRS gene. Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. The protein encoded by this gene is a multifunctional...
| Schlagworte: | Anti-EPRS, Anti-PIG32, Anti-GluRS, EC=6.1.1.17, Anti-Proline--tRNA ligase, Anti-Glutamate--tRNA ligase, Anti-Prolyl-tRNA... |
| Anwendung: | WB, IHC (paraffin), IF, FC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
772,00 €