Zu "K14158" wurden 30 Artikel gefunden!
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Sotagliflozin
Artikelnummer: TGM-T3547-100mg
Description: Sotagliflozin (LP-802034) is an orally bioavailable inhibitor of the sodium-glucose co-transporter subtype 1 (SGLT1) and 2 (SGLT2), with potential antihyperglycemic activity. Target: SGLT. Smiles: CCOc1ccc(Cc2cc(ccc2Cl)[C@@H]2O[C@H](SC)[C@@H](O)[C@H](O)[C@H]2O)cc1. References: Zambrowicz B, et al. Clin...
| Schlagworte: | LX-4211, LP-802034 |
| Anwendung: | Targets solute carrier family 5 (sodium/glucose cotransporter), member 1 (SLC5A1, SGLT1) |
| CAS | 1018899-04-1 |
| MW: | 424.94 D |
ab 40,00 €
Phlorizin
Artikelnummer: TGM-T2922-1g
Description: Phlorizin (Phloridzin) is a non-selective SGLT inhibitor found in apple, for hSGLT1( Ki=300 nM) and hSGLT2( Ki=39 nM) . Target: ATPase, SGLT. Smiles: C(CCC1=CC=C(O)C=C1)(=O)C2=C(O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)C=C(O)C=C2O. References: Taton J, et al. Endokrynol Pol, 2010, 61(3), 303-310.
| Schlagworte: | NSC 2833, Phloridzin, Floridzin |
| Anwendung: | SLGT1/2 inhibition |
| CAS | 60-81-1 |
| MW: | 436.41 D |
ab 46,00 €
Anti-SLC5A1
Artikelnummer: CSB-PA218464.100
Host Species: Rabbit. Isotype: IgG. Buffer: Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen Affinity Purified. Target Name: SLC5A1. Antigen Species: Human
| Schlagworte: | Anti-NAGT, Anti-SLC5A1, Anti-Na(+)/glucose cotransporter 1, Anti-Sodium/glucose cotransporter 1, Anti-Solute carrier... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
283,00 €
Phlorizin
Artikelnummer: Cay11576-1
Sodium-glucose cotransporter 1 (SGLT1) is a high affinity, low capacity transporter abundant in the small intestine, with some expression in the kidney as well. SGLT2 is a low affinity, high capacity transporter in the kidney that accounts for approximately 90% of glucose reabsorption into the blood stream....
| Schlagworte: | Floridzin, NSC 2833, 1-[2-(beta-D-glucopyranosyloxy)-4,6-dihydroxyphenyl]-3-(4-hydroxyphenyl)-1-propanone |
| Anwendung: | SLGT1/2 inhibition |
| CAS | 60-81-1 |
| MW: | 436.4 D |
ab 100,00 €
Anti-SGLT1
Artikelnummer: NSJ-R31368
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Sodium/glucose cotransporter 1, also known as NAGT or SGLT1 is a protein that in humans is encoded by the SLC5A1 gene. This gene encodes a member of the sodium-dependent glucose transporter (SGLT) family. The encoded integral membrane protein is the primary...
| Schlagworte: | Anti-NAGT, Anti-Na(+)/glucose cotransporter 1, Anti-Sodium/glucose cotransporter 1, Anti-Solute carrier family 5 member 1,... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
772,00 €
Sotagliflozin
Artikelnummer: Cay19141-10
Sotagliflozin is an inhibitor of sodium-glucose cotransporters (SGLTs, IC50s = 36 and 1.8 nM for human SGLT1 and SGLT2, respectively). It increases plasma glucagon-like peptide 1 (GLP-1) and peptide YY (PYY) levels, as well as glucose levels in the small intestine, cecum, and colon, in mice when administered at a...
| Schlagworte: | LX4211, LP 802034, methyl 5S-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-1-thio-beta-L-xylopyranoside |
| Anwendung: | SGLT1 / SGLT2 inhibitor |
| CAS | 1018899-04-1 |
| MW: | 424.9 D |
ab 52,00 €
Anti-SGLT1
Artikelnummer: ARG10837.50
Protein function: Actively transports glucose into cells by Na(+) cotransport with a Na(+) to glucose coupling ratio of 2:1. Efficient substrate transport in mammalian kidney is provided by the concerted action of a low affinity high capacity and a high affinity low capacity Na(+)/glucose cotransporter arranged in...
| Schlagworte: | Anti-NAGT, Anti-SLC5A1, Anti-Na(+)/glucose cotransporter 1, Anti-Sodium/glucose cotransporter 1, Anti-Solute carrier... |
| Anwendung: | ICC, IF, IHC (paraffin), WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | baboon, human, monkey, mouse, swine, rat |
592,00 €
Anti-Slc5a1
Artikelnummer: NSJ-R34386-100UG
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Solute carrier family 5 (sodium/glucose cotransporter), member 1 Protein function: Actively transports glucose into cells by Na(+) cotransport with a Na(+) to glucose coupling ratio of 2:1....
| Schlagworte: | Anti-Sglt1, Anti-Slc5a1, Anti-Na(+)/glucose cotransporter 1, Anti-Sodium/glucose cotransporter 1, Anti-Solute carrier... |
| Anwendung: | WB, IHC, ELISA (peptide) |
| Wirt: | Goat |
| Spezies-Reaktivität: | rat |
790,00 €
Anti-SLC5A1
Artikelnummer: ATA-HPA051805.100
Protein function: Actively transports glucose into cells by Na(+) cotransport with a Na(+) to glucose coupling ratio of 2:1. Efficient substrate transport in mammalian kidney is provided by the concerted action of a low affinity high capacity and a high affinity low capacity Na(+)/glucose cotransporter arranged in...
| Schlagworte: | Anti-NAGT, Anti-SLC5A1, Anti-Na(+)/glucose cotransporter 1, Anti-Sodium/glucose cotransporter 1, Anti-Solute carrier... |
| Anwendung: | IHC, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 320,00 €
Anti-SLC5A1
Artikelnummer: ATA-HPA055106.100
Protein function: Actively transports glucose into cells by Na(+) cotransport with a Na(+) to glucose coupling ratio of 2:1. Efficient substrate transport in mammalian kidney is provided by the concerted action of a low affinity high capacity and a high affinity low capacity Na(+)/glucose cotransporter arranged in...
| Schlagworte: | Anti-NAGT, Anti-SLC5A1, Anti-Na(+)/glucose cotransporter 1, Anti-Sodium/glucose cotransporter 1, Anti-Solute carrier... |
| Anwendung: | ICC, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 320,00 €
Licogliflozin (mixed isomers)
Artikelnummer: Cay35772-1
Licogliflozin (mixed isomers) is a mixture of isomers of the sodium-glucose cotransporter 1 (SGLT1) and SGLT2 inhibitor licogliflozin.Formal Name: (2S,3S,4S,5R,6R)-2-(3-((2,3-dihydrobenzo[b][1,4]dioxin-6-yl)methyl)-4-ethylphenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol. CAS Number: 2730989-98-5. Synonyms:...
| Schlagworte: | LIK-066,... |
| Anwendung: | Licogliflozin isomers mixture, SGLT1 / SGLT2 inhibitor |
| CAS | 2730989-98-5 |
| MW: | 416.5 D |
ab 70,00 €
Human SGLT1 (Sodium/Glucose Cotransporter 1) ELISA Kit
Artikelnummer: ELK-ELK4104.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human SGLT1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human SGLT1. Next,...
| Schlagworte: | NAGT, Na(+)/glucose cotransporter 1, Sodium/glucose cotransporter 1, Solute carrier family 5 member 1, High affinity... |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
ab 374,00 €