Zu "K13985" wurden 21 Artikel gefunden!
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ARN19874
Artikelnummer: TGM-T14321-10mg
Description: ARN19874 is a selective, reversible uncompetitive inhibitor of N-acylphosphatidylethanolamine phospholipase D (NAPE-PLD) activity, with an IC50 of approximately 34 µM[1]. Target: Others. Smiles: O=C1C=2C(=CC=C(S(NC3=CC=C(C=C3)C=4C=CN=CC4)(=O)=O)C2)NC(=O)N1. References: Castellani B, et al. Synthesis and...
| Anwendung: | NAPE-PLD inhibitor |
| CAS | 2190502-57-7 |
| MW: | 394.4 D |
ab 77,00 €
LEI-401
Artikelnummer: TGM-T38001-1mg
Description: LEI-401 is a selective and potent NAPE-PLD inhibitor that crosses the blood-brain barrier (IC50: 27 nM).LEI-401 reduces the level of n-acylethanolamines (NAEs) in the brain of free-ranging mice and modulates their emotional behaviour. Target: Phospholipase. Smiles:...
| Schlagworte: | LEI 401 |
| Anwendung: | NAPE-PLD inhibitor |
| CAS | 2393840-15-6 |
| MW: | 421.54 D |
52,00 €
VU534
Artikelnummer: TGM-T77594-100mg
Description: VU534 is a NAPE-PLD agonist with an EC50 of 0.30 µM.VU534 is a dual inhibitor of FAAH and sEH, with an IC50 of 1.2 µM for sEH.VU534 is used in diseases related to cardiometabolism. Target: Phospholipase, FAAH, Epoxide Hydrolase. Smiles: CC1=CC2=C(SC(NC(=O)C3CCN(CC3)S(=O)(=O)C3=CC=C(F)C=C3)=N2)C(C)=C1....
| Anwendung: | NAPE-PLD activator |
| CAS | 923509-20-0 |
| MW: | 447.55 D |
ab 37,00 €
VU534
Artikelnummer: Cay39744-10
VU534 is an activator of N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D (NAPE-PLD), which hydrolyzes NAPEs into N-acyl ethanolamines (NAEs) and phosphatidic acid. It increases NAPE-PLD activity in cell-free assays (EC50s = 0.3 and 0.93 µM for the recombinant mouse and human enzymes, respectively). VU534...
| Schlagworte: | N-Acyl-Phosphatidylethanolamine-Hydrolysing Phospholipase D Activator 534, NAPE-PLD Activator 534,... |
| Anwendung: | NAPE-PLD activator |
| CAS | 923509-20-0 |
| MW: | 447.5 D |
ab 115,00 €
Anti-NAPE-PLD (Internal)
Artikelnummer: Cay10305-1
N-acylethanolamines (NAEs) are involved in diverse biological processes such as inflammatory regulation, apoptosis, and tissue degeneration. In animals, NAEs are mainly biosynthesized via a membrane phospholipid-dependent pathway, which is the enzymatic hydrolysis of N-acyl-phosphatidylethanolamine (NAPE). The...
| Schlagworte: | Anti-NAPEPLD, Anti-C7orf18, Anti-NAPE-PLD, Anti-NAPE-PLD, Anti-NAPE-hydrolyzing phospholipase D, Anti-NAPE-hydrolyzing... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
498,00 €
Anti-NAPE-PLD (N-Term)
Artikelnummer: Cay10306-1
N-acylethanolamines (NAEs) are involved in diverse biological processes such as inflammatory regulation, apoptosis, and tissue degeneration. In animals, NAEs are mainly biosynthesized via a membrane phospholipid-dependent pathway, which is the enzymatic hydrolysis of N-acyl-phosphatidylethanolamine (NAPE). The...
| Schlagworte: | Anti-NAPEPLD, Anti-C7orf18, Anti-NAPE-PLD, Anti-NAPE-PLD, Anti-NAPE-hydrolyzing phospholipase D, Anti-NAPE-hydrolyzing... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
431,00 €
LEI-401
Artikelnummer: Cay31108-5
LEI-401 is an inhibitor of N-acyl phosphatidylethanolamine phospholipase D (NAPE-PLD, IC50 = 0.86 µM in HEK293T cell membranes expressing the recombinant human enzyme). It is selective for NAPE-PLD over human cannabinoid (CB) receptor 1 (CB1), CB2, type IVE phospholipase A2, monoacylglycerol lipase (MAGL), and...
| Schlagworte: | N-(cyclopropylmethyl)-6-[(3S)-3-hydroxy-1-pyrrolidinyl]-2-[(3S)-3-phenyl-1-piperidinyl]-4-pyrimidinecarboxamide |
| Anwendung: | NAPE-PLD inhibitor |
| CAS | 2393840-15-6 |
| MW: | 421.5 D |
ab 75,00 €
ARN19874
Artikelnummer: Cay24283-1
ARN19874 is an inhibitor of N-acyl phosphatidylethanolamine phospholipase D (NAPE-PLD, IC50 = 33.7 µM). It is selective for NAPD-PLD over carbonic anhydrase II, neutral endopeptidase, and angiotensin-converting enzyme (ACE) up to 50 µM. ARN19874 (50 µM) increases the levels of certain NAPE substrates and decreases...
| Schlagworte: | 1,2,3,4-tetrahydro-2,4-dioxo-N-[4-(4-pyridinyl)phenyl]-6-quinazolinesulfonamide |
| Anwendung: | NAPE-PLD inhibitor |
| CAS | 2190502-57-7 |
| MW: | 394.4 D |
ab 44,00 €
Anti-NAPE PLD
Artikelnummer: ARG56468.250
Protein function: Hydrolyzes N-acyl-phosphatidylethanolamines (NAPEs) to produce N-acylethanolamines (NAEs) and phosphatidic acid. Responsible for the generation of anandamide (N- arachidonoylethanolamine), the ligand of cannabinoid and vanilloid receptors. [The UniProt Consortium]
| Schlagworte: | Anti-C7orf18, Anti-NAPEPLD, Anti-NAPE-PLD, EC=3.1.4.54, Anti-NAPE-hydrolyzing phospholipase D, Anti-N-acyl... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
707,00 €
Anti-NAPE PLD
Artikelnummer: ARG56469.250
Protein function: Hydrolyzes N-acyl-phosphatidylethanolamines (NAPEs) to produce N-acylethanolamines (NAEs) and phosphatidic acid. Responsible for the generation of anandamide (N- arachidonoylethanolamine), the ligand of cannabinoid and vanilloid receptors. [The UniProt Consortium]
| Schlagworte: | Anti-C7orf18, Anti-NAPEPLD, Anti-NAPE-PLD, EC=3.1.4.54, Anti-NAPE-hydrolyzing phospholipase D, Anti-N-acyl... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat, bovine |
707,00 €
Anti-NAPEPLD
Artikelnummer: G-PACO37130.50
NAPEPLD Antibody is a IgG polyclonal antibody from Assay Genie with reactivity against Human, Mouse and for use in ELISA, WB applications. NAPEPLD Antibody is a high quality polyclonal antibody for research use only.. Protein function: D-type phospholipase that hydrolyzes N-acyl- phosphatidylethanolamines (NAPEs) to...
| Schlagworte: | Anti-C7orf18, Anti-NAPEPLD, Anti-NAPE-PLD, Anti-NAPE-hydrolyzing phospholipase D, Anti-N-acyl phosphatidylethanolamine... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
384,00 €
Anti-NAPEPLD
Artikelnummer: ATA-HPA019832.100
Protein function: D-type phospholipase that hydrolyzes N-acyl- phosphatidylethanolamines (NAPEs) to produce bioactive N- acylethanolamines/fatty acid ethanolamides (NAEs/FAEs) and phosphatidic acid (PubMed:14634025, PubMed:16527816, PubMed:27571266, PubMed:25684574). Cleaves the terminal phosphodiester bond of...
| Schlagworte: | Anti-NAPEPLD, Anti-C7orf18, Anti-NAPE-PLD, Anti-NAPE-hydrolyzing phospholipase D, Anti-N-acyl phosphatidylethanolamine... |
| Anwendung: | ICC, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 358,00 €