Zu "K13780" wurden 33 Artikel gefunden!
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LAT1-IN-1
Artikelnummer: TGM-T11820-25mg
Description: LAT1-IN-1 (BCH) (BCH) significantly inhibit cellular uptake of amino acids and mTOR phosphorylation, which induces the suppression of cancer growth and apoptosis. is a selective and competitive inhibitor of large neutral amino acid transporter 1 (LAT1). Target: Apoptosis, Others. Smiles:...
| Schlagworte: | BCH |
| Anwendung: | LAT1 inhibitor |
| CAS | 20448-79-7 |
| MW: | 155.19 D |
ab 37,00 €
KMH-233
Artikelnummer: TGM-T32404-100mg
Description: KMH-233 is a potent selective LAT1 inhibitor 1 that inhibits the uptake of LAT1 substrate, L-leucine, and cell growth. Even at low concentrations (25 µM), it significantly enhanced the efficacy of betastatin and cisplatin. Target: Others. Smiles:...
| Schlagworte: | KMH233 |
| Anwendung: | LAT1 inhibitor |
| CAS | 1941174-13-5 |
| MW: | 587.58 D |
ab 1.530,00 €
SLC7A5 Protein, Human, Recombinant (His & Myc & SUMO)
Artikelnummer: TGM-TMPH-01604-100ug
Description: SLC7A5 Protein, Human, Recombinant (His & Myc & SUMO) is expressed in E. coli expression system with N-10xHis-SUMO and C-Myc tag. The predicted molecular weight is 19.7 kDa and the accession number is Q01650.
| Schlagworte: | y+ system cationic amino acid transporter, SLC7A5, Solute carrier family 7 member 5, 4F2 light chain, L-type amino acid... |
| MW: | 19.7 kD |
ab 281,00 €
JPH203
Artikelnummer: TGM-TQ0081-100mg
Description: JPH203 (KYT-0353) is a potent and specific inhibitor of L-type amino acid transporter protein 1 (LAT-1). JPH203 inhibits cellular uptake of leucine, inhibits cell proliferation, induces apoptosis, and possesses anti-inflammatory and anti-tumor activities. Target: Others. Smiles:...
| Schlagworte: | KYT-0353 |
| Anwendung: | L-type amino acid transporter 1 (LAT1) inhibitor |
| CAS | 1037592-40-7 |
| MW: | 472.32 D |
ab 43,00 €
Anti-SLC7A5
Artikelnummer: CSB-PA057466.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: SLC7A5. Antigen Species: Human
| Schlagworte: | Anti-E16, Anti-hLAT1, Anti-4F2LC, Anti-4F2 LC, Anti-SLC7A5, Anti-4F2 light chain, Anti-CD98 light chain, Anti-Integral... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 167,00 €
Anti-SLC7A5
Artikelnummer: CSB-PA068714.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: SLC7A5. Antigen Species: Human
| Schlagworte: | Anti-E16, Anti-hLAT1, Anti-4F2LC, Anti-4F2 LC, Anti-SLC7A5, Anti-4F2 light chain, Anti-CD98 light chain, Anti-Integral... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 167,00 €
Anti-SLC7A5
Artikelnummer: CSB-PA157177.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: SLC7A5. Antigen Species: Human
| Schlagworte: | Anti-E16, Anti-hLAT1, Anti-4F2LC, Anti-4F2 LC, Anti-SLC7A5, Anti-4F2 light chain, Anti-CD98 light chain, Anti-Integral... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 167,00 €
KMH-233
Artikelnummer: Cay31032-1
KMH-233 is an inhibitor of L-type amino acid transporter 1 (LAT1, IC50 = 18.2 µM). It is selective for LAT1 over LAT2 (IC50 = >1,000 µM). KMH-233 (25 and 100 µM) reduces the viability of MCF-7 cells and enhances cell death induced by bestatin (Cay-21217, Cay-70520) or cisplatin (Cay-13119) in the same cells. It also...
| Schlagworte: | 3-[[[2,4-dicyano-3-[4-[2-(methylamino)-2-oxoethoxy]phenyl]pyrido[1,2-a]benzimidazol-1-yl]amino]carbonyl]-L-phenylalanine |
| Anwendung: | LAT1 inhibitor |
| CAS | 1941174-13-5 |
| MW: | 587.6 D |
217,00 €
Large neutral amino acids transporter small subunit 1...
Artikelnummer: CSB-EP021717HU.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 16-50aa. Protein Length: Partial. Tag Info: N-terminal 10xHis-SUMO-tagged and C-terminal Myc-tagged. Target Protein Sequence: AEEKEEAREK MLAAKSADGS APAGEGEGVT LQRNI. Purity: Greater than 90% as determined by SDS-PAGE. Endotoxin: Not test. Biological...
| Schlagworte: | E16, 4F2LC, hLAT1, SLC7A5, 4F2 LC, 4F2 light chain, CD98 light chain, Integral membrane protein E16, L-type amino acid... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 19.7 kD |
ab 292,00 €
Large neutral amino acids transporter small subunit 1...
Artikelnummer: CSB-EP021717HUa3.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 16-50aa. Protein Length: Partial. Tag Info: N-terminal 6xHis-SUMO-tagged and C-terminal Myc-tagged. Target Protein Sequence: AEEKEEAREK MLAAKSADGS APAGEGEGVT LQRNI. Purity: Greater than 90% as determined by SDS-PAGE. Endotoxin: Not test. Biological...
| Schlagworte: | E16, 4F2LC, hLAT1, SLC7A5, 4F2 LC, 4F2 light chain, CD98 light chain, Integral membrane protein E16, L-type amino acid... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 18.0 kD |
ab 292,00 €
BCH
Artikelnummer: Cay15249-25
The L-type amino acid transporters (LATs) are Na+-dependent neutral amino acid transporters. They include four members in two sub-families, with LAT1 and LAT2 belonging to solute carrier (SLC) family 7 and LAT3 and LAT4 being members of SLC43. LAT1 is overexpressed in many tumors and contributes to ribosome...
| Schlagworte: | 2-amino-2-Norbornanecarboxylic Acid, 2-amino-bicyclo[2.2.1]heptane-2-carboxylic acid |
| Anwendung: | LAT1 inhibitor |
| CAS | 20448-79-7 |
| MW: | 155.2 D |
ab 45,00 €
JPH203
Artikelnummer: Cay29715-5
JPH203 is an inhibitor of L-type amino acid transporter 1 (LAT1, IC50 = 0.14 µM for 14C-leucine uptake in S2 cells expressing the human transporter). It is selective for LAT1 over LAT2 (IC50 = >10 µM). JPH203 inhibits 14C-leucine uptake by, and growth of, HT-29 cells (IC50s = 0.06 and 4.1 µM, respectively). It...
| Schlagworte: | KYT-0353, O-[(5-amino-2-phenyl-7-benzoxazolyl)methyl]-3,5-dichloro-L-tyrosine |
| Anwendung: | L-type amino acid transporter 1 (LAT1) inhibitor |
| CAS | 1037592-40-7 |
| MW: | 472.3 D |
ab 44,00 €