Zu "K13762" wurden 91 Artikel gefunden!
Für die Filterung wurden keine Ergebnisse gefunden!
Tadalafil
Artikelnummer: TGM-T1398-100mg
Description: Tadalafil (IC-351) is a carboline-based compound with vasodilatory activity that selectively inhibits the cyclic guanosine monophosphate (cGMP)-specific type 5 phosphodiesterase (PDE-5), preventing cGMP degradation in the smooth muscle of the corpus cavernosa and corpus spongiosum of the penis, thereby...
| Schlagworte: | Cialis, IC-351 |
| Anwendung: | Targets cGMP-specific 3',5'-cyclic phosphodiesterase [EC:3.1.4.35] (PDE5) |
| CAS | 171596-29-5 |
| MW: | 389.4 D |
ab 33,00 €
MY-5445
Artikelnummer: TGM-T16164-10mg
Description: MY-5445 (N-(3-chlorophenyl)-4-phenylphthalazin-1-amine) is a specific inhibitor of phosphodiesterase type 5 (PDE5). MY-5445 selectively inhibits cGMP PDE (Ki:1.3 µM). Target: PDE. Smiles: Clc1cccc(Nc2nnc(-c3ccccc3)c3ccccc23)c1. References: Nagendran J, et al. Phosphodiesterase type 5 is highly expressed...
| Schlagworte: | N-(3-chlorophenyl)-4-phenylphthalazin-1-amine |
| Anwendung: | PDE5 inhibitor |
| CAS | 78351-75-4 |
| MW: | 331.8 D |
ab 31,00 €
Sildenafil Chlorosulfonyl
Artikelnummer: TGM-T36444-1g
Description: Sildenafil chlorosulfonyl is a synthetic intermediate in the synthesis of the phosphodiesterase 5 (PDE5) inhibitor sildenafil .1It is also a potential impurity found in commercial preparations of sildenafil. Target: Others. Smiles: CCCc1nn(C)c2c1nc([nH]c2=O)-c1cc(ccc1OCC)S(Cl)(=O)=O. References:...
| Anwendung: | Sildenafil synthesis intermediate |
| CAS | 139756-22-2 |
| MW: | 410.88 D |
ab 91,00 €
PF-00489791
Artikelnummer: TGM-T28360-10mg
Description: PF-00489791 (PF4634817) is a long-acting PDE5 inhibitor with hypotensive activity for the study of diabetic nephropathy. Target: PDE. Smiles: C(NS(C)(=O)=O)(=O)C=1C=2C(=C(NC3=CC(C)=CC=N3)N=C(N(CC)C)N2)N(CCOCC)N1. References: Scheele W, Diamond S, Gale J, Clerin V, Tamimi N, Le V, Walley R, Grover-Páez...
| Schlagworte: | PF4634817, PF 00489791, PF-4634817, PF 4634817, PF00489791 |
| Anwendung: | PDE5A inhibitor |
| CAS | 853003-48-2 |
| MW: | 476.55 D |
ab 103,00 €
Icariin
Artikelnummer: TGM-T2855-100mg
Description: Icariin (Ieariline) belongs to the flavonol glycoside group of natural products, can inhibit PDE5 and PDE4 activity (IC50=432/73.50 µM), is also a PPARalpha activator. Icariin can increase cardiovascular and cerebrovascular blood flow, promote hematopoiesis, immunity and bone metabolism. Target:...
| Schlagworte: | Ieariline |
| Anwendung: | PDE5 inhibitor, Metabolic studies |
| CAS | 489-32-7 |
| MW: | 676.66 D |
ab 33,00 €
N-Desmethyl Sildenafil
Artikelnummer: TGM-T36061-100mg
Description: N-Desmethyl Sildenafil is the major metabolite of Sildenafil, a potent phosphodiesterase type 5 (PDE5) inhibitor. Target: Drug Metabolite. Smiles: CCCc1nn(C)c2c1[nH]c(nc2=O)-c1cc(ccc1OCC)S(=O)(=O)N1CCNCC1. References: Péter Barabás, et al. Sildenafil, N-desmethyl-sildenafil and Zaprinast enhance...
| Schlagworte: | UK-103,320, Desmethylsildenafil |
| Anwendung: | Sildenafil metabolite |
| CAS | 139755-82-1 |
| MW: | 460.55 D |
ab 41,00 €
Vardenafil hydrochloride trihydrate
Artikelnummer: TGM-T4097-100mg
Description: Vardenafil hydrochloride trihydrate (BAY38-9456) is a new type PDE inhibitor with IC50 of 0.7 and 180 nM for PDE5 and PDE1, respectively. Target: PDE. Smiles: O.O.O.Cl.CCCc1nc(C)c2n1nc([nH]c2=O)-c1cc(ccc1OCC)S(=O)(=O)N1CCN(CC)CC1. References: Saenz de Tejada I, et al. Int J Impot Res, 2001, 13(5), 282-290.
| Schlagworte: | Vardenafil HCl Trihydrate, BAY38-9456 |
| Anwendung: | PDE5 inhibitor |
| CAS | 330808-88-3 |
| MW: | 579.11 D |
ab 39,00 €
Nor-Acetildenafil
Artikelnummer: TGM-T41108-1mg
Description: Nor-Acetildenafil is a derivative of Acetildenafil, a synthetic phosphodiesterase inhibitor. Target: Others. Smiles: CCCc1nn(C)c2c1nc([nH]c2=O)-c1cc(ccc1OCC)C(=O)CN1CCN(C)CC1. References: Samuel R Gratz, et al. Accurate Mass Measurement Using Fourier Transform Ion Cyclotron Resonance Mass Spectrometry...
| Anwendung: | Sildenafil derivative |
| CAS | 949091-38-7 |
| MW: | 452.55 D |
ab 289,00 €
Vardenafil dihydrochloride
Artikelnummer: TGM-T4480-100mg
Description: Vardenafil dihydrochloride (Levitra) is a new type PDE inhibitor with IC50 of 0.7 and 180 nM for PDE5 and PDE1, respectively. Target: PDE. Smiles: Cl.Cl.CCCc1nc(C)c2n1[nH]c(nc2=O)-c1cc(ccc1OCC)S(=O)(=O)N1CCN(CC)CC1. References: Saenz d T I, et al. The phosphodiesterase inhibitory selectivity and the in...
| Schlagworte: | Vardenafil Hydrochloride, Levitra |
| Anwendung: | Targets cGMP-specific 3',5'-cyclic phosphodiesterase [EC:3.1.4.35] (PDE5) |
| CAS | 224789-15-5 |
| MW: | 561.52 D |
ab 46,00 €
Hydroxychlorodenafil
Artikelnummer: TGM-T70795-100mg
Description: Hydroxychlorodenafil is a derivative of the phosphodiesterase 5 (PDE5) inhibitor sildenafil. Target: Others. Smiles: C(CC)C=1C2=C(C(=O)N=C(N2)C3=C(OCC)C=CC(C(CCl)O)=C3)N(C)N1
| Anwendung: | Phosphodiesterase 5 (PDE5) inhibitor sildenafil derivative |
| CAS | 1391054-00-4 |
| MW: | 390.86 D |
ab 193,00 €
Thiosildenafil
Artikelnummer: TGM-T71820-10mg
Description: Thiosildenafil is a derivative of the phosphodiesterase 5 (PDE5) inhibitor sildenafil. Target: Others. Smiles: O(CC)C1=C(C=C(S(=O)(=O)N2CCN(C)CC2)C=C1)C=3NC4=C(C(=S)N3)N(C)N=C4CCC
| Anwendung: | PDE5 inhibitor derivative |
| CAS | 479073-79-5 |
| MW: | 490.64 D |
ab 106,00 €
Amino Tadalafil
Artikelnummer: TGM-T7542-100mg
Description: Amino tadalafil is a potent phosphodiesterase 5 (PDE5) inhibitor. Target: PDE. Smiles: NN1CC(=O)N2[C@H](Cc3c([nH]c4ccccc34)[C@H]2c2ccc3OCOc3c2)C1=O. References: Hadwiger M E , Trehy M L , Ye W , et al. Identification of amino-tadalafil and rimonabant in electronic cigarette products using high pressure...
| Anwendung: | Tadalafil analog |
| CAS | 385769-84-6 |
| MW: | 390.39 D |
ab 35,00 €