Zu "K13755" wurden 83 Artikel gefunden!
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Mouse PDE1C (Phosphodiesterase 1C, Calmodulin Dependent)...
Artikelnummer: ELK-ELK7185.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse PDE1C. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse PDE1C. Next,...
| Schlagworte: | Cam-PDE 1C, Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | mouse |
ab 365,00 €
Human PDE1A (Phosphodiesterase 1A, Calmodulin Dependent)...
Artikelnummer: ELK-ELK4781.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human PDE1A. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human PDE1A. Next,...
| Schlagworte: | hCam-1, Cam-PDE 1A, 61 kDa Cam-PDE, Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide... |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
ab 365,00 €
8-Methoxymethyl-3-isobutyl-1-methylxanthine
Artikelnummer: Cay39151-1
8-Methoxymethyl-3-isobutyl-1-methylxanthine is an inhibitor of phosphodiesterase 1 (PDE1, IC50 = 5 µM) and a derivative of IBMX (Cay-13347). It is selective for PDE1 over PDE2, PDE3, and PDE4 but also inhibits PDE5 (IC50s = 37, >400, >400, and 2 µM, respectively). 8-Methoxymethyl-3-isobutyl-1-methylxanthine (30 µM)...
| Schlagworte: | 8-MeOMeMIX, 8-methoxymethyl IBMX, 8-MM-IBMX, MMPX,... |
| Anwendung: | PDE1 inhibitor |
| CAS | 78033-08-6 |
| MW: | 266.3 D |
ab 62,00 €
Vinpocetine
Artikelnummer: AG-CN2-0454-M020
White to slightly yellow crystalline powder. Soluble in DMSO, dichloromethane, acetone or 100% ethanol. Insoluble in water. Selective Ca2+-calmodulin dependent cGMP-phosphodiesterase (PDE1) inhibitor. Shows vasorelaxant activity, Neuroprotective agent, Selectively inhibits voltage-sensitive 2+ channels, Potent...
| Schlagworte: | (3alpha,16alpha)-Eburnamenine-14-carboxylic acid ethyl ester, Ethyl apovincaminate, RGH-4405, TCV 3B, AY 27255 |
| Anwendung: | PDE1 inhibitor |
| CAS | 42971-09-5 |
| MW: | 350,5 D |
ab 39,00 €
PDE1B, active human recombinant protein
Artikelnummer: BPS-60011
Active human PDE1B (GenBank Accession No. NM_000924), full length with N-terminal GST tag, MW= 87 kDa, expressed in a Baculovirus infected Sf9 cell expression system.
| Schlagworte: | PDES1B, Cam-PDE 1B, 63 kDa Cam-PDE, Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide... |
| Anwendung: | Enzyme kinetics, inhibitor screening |
| MW: | 87 kD |
672,00 €
PDE1A Assay Kit
Artikelnummer: BPS-60310
Phosphodiesterases (PDEs) play an important role in dynamic regulation of cAMP and cGMP signaling. PDE1A1 is a calmodulin-dependent PDE and expressed in lung and heart. PDE1A1 is believed to regulate vascular smooth muscle contraction and may play a role in sperm function. The PDE1A Assay Kit is designed for...
| Schlagworte: | inhibitor screening, assay kit, PDE1A, |
| Anwendung: | Enzyme kinetics, inhibitor screening, HTS |
| Spezies-Reaktivität: | human |
599,00 €
PDE1B assay kit
Artikelnummer: BPS-60311
The PDE1B Assay Kit is designed for identification of PDE1B inhibitors using fluorescence polarization. The assay is based on the binding of a fluorescent nucleotide monophosphate generated by PDE1B to the binding agent. PDE1B is a calcium-dependent cyclic nucleotide phosphodiesterase that is highly expressed in the...
| Schlagworte: | inhibitor screening, assay kit, PDE1B, |
| Anwendung: | PDE1B assays, inhibitor screening, FP |
599,00 €
Vinpocetine
Artikelnummer: Cay19578-100
Vinpocetine is a semisynthetic alkaloid commonly used as an inhibitor of phosphodiesterase 1 (PDE1), blocking the hydrolysis of both cAMP and cGMP (Ki = 14 µM). In addition to its use as a selective PDE1 inhibitor in basic research, vinpocetine has diverse cerebral and neurological effects in vivo. Vinpocetine also...
| Schlagworte: | Apovincaminic Acid ethyl ester, AY 27255, RGH-4405, (3alpha,16alpha)-eburnamenine-14-carboxylic acid, ethyl ester |
| Anwendung: | Neuroprotectant, PDE1 inhibitor |
| CAS | 42971-09-5 |
| MW: | 350.5 D |
ab 68,00 €
W-5 . hydrochloride
Artikelnummer: AG-CR1-0003-M005
Calmodulin antagonist, Cell proliferation inhibitor, Ca2????regulated phosphodiesterase (PDE I) inhibitor, Myosin light chain kinase (MLCK) inhibitor.
| Schlagworte: | N-(6-Aminohexyl)-1-naphthalenesulfonamide . HCl |
| Anwendung: | Calmodulin antagonist, Cell proliferation inhibitor |
| CAS | 61714-25-8 |
| MW: | 306,4 D |
ab 55,00 €
ITI214
Artikelnummer: Cay30376-5
ITI214 is an inhibitor of phosphodiesterase 1 (PDE1, Ki = 0.058 nM). It is selective for PDE1 over PDE2A, -3B, -4A, -5A, -6, -7B, -8A, -9A, -10A, and -11A (Kis = 0.16-18 µM). ITI214 (3 and 6 mg/kg) enhances novel object recognition in rats. It increases prefrontal cortex cAMP and cGMP levels in mice when...
| Schlagworte: | (6aR,9aS)-2-[[4-(6-fluoro-2-pyridinyl)phenyl]methyl]-5,6a,7,8,9,9a-hexahydro-5-methyl-3-(phenylamino)-cyclopent[4,5]imidaz... |
| Anwendung: | PDE1 inhibitor |
| CAS | 1642303-38-5 |
| MW: | 605.6 D |
ab 109,00 €
Anti-PDE1A
Artikelnummer: ARG10791.50
Protein function: Cyclic nucleotide phosphodiesterase with a dual- specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. Has a higher affinity for cGMP than for cAMP. [The UniProt Consortium]
| Schlagworte: | Anti-Pde1a, Anti-Cam-PDE 1A, EC=3.1.4.17, Anti-61 kDa Cam-PDE, Anti-Calcium/calmodulin-dependent 3',5'-cyclic nucleotide... |
| Anwendung: | IF, ELISA, ICC, IF, IHC, IP, WB, DB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
576,00 €
Anti-PDE1B
Artikelnummer: ARG10792.50
Protein function: Cyclic nucleotide phosphodiesterase with a dual- specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. Has a preference for cGMP as a substrate. [The UniProt Consortium]
| Schlagworte: | Anti-PDE1B, Anti-PDE1B1, Anti-Cam-PDE 1B, EC=3.1.4.17, Anti-63 kDa Cam-PDE, Anti-Calcium/calmodulin-dependent 3',5'-cyclic... |
| Anwendung: | IF, ELISA, ICC, IF, IHC (paraffin), IP, WB, DB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
576,00 €