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Zu "K13298" wurden 30 Artikel gefunden!
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NEU
Artikelnummer: Cay10005169-5
Quercetin is an abundant flavonoid that has been isolated from a variety of fruits and vegetables and has diverse biological activities, including antioxidant, anticancer, and anti-inflammatory properties. Quercetin (5-100 mg/kg) reduces autophagy, decreases the levels of reactive oxygen species (ROS) and...
Schlagworte: | 2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-4H-1-benzopyran-4-one, hydrate |
Anwendung: | Bioactìve flavonoid |
CAS | 849061-97-8 |
MW: | 302.2 D |
28,00 €
Artikelnummer: Cay13347-100
IBMX is a widely-used non-specific inhibitor of cyclic AMP and cyclic GMP phosphodiesterases (PDEs) (IC50 = 19, 50, 18, 13, 32, 7, and 50 µM for PDE1, PDE2, PDE3, PDE4, PDE5, PDE7, and PDE11, respectively). PDE8A, PDE8B, and PDE9 are insensitive to IBMX. By inhibiting PDEs, IBMX increases cellular cAMP and cGMP...
Schlagworte: | 1-Methyl-3-Isobutylxanthine, Isobutylmethylxanthine, NSC 165960, SC-2964,... |
Anwendung: | PDE inhibitor |
CAS | 28822-58-4 |
MW: | 222.3 D |
ab 52,00 €
Artikelnummer: TGM-T1713-100mg
Description: IBMX (Methylisobutylxanthine) is a broad-spectrum phosphodiesterase (PDE) inhibitor with inhibitory activity against PDE3, PDE4, and PDE5 (IC50=6.5/26.3/31.7 µM). IBMX enhances the intracellular cAMP level. Target: PDE. Smiles: CC(C)Cn1c2[nH]cnc2c(=O)n(C)c1=O. References: Wei Y, et al. Angiotensin II...
Schlagworte: | 3-Isobutyl-1-methylxanthine, 1-Methyl-3-Isobutylxanthine, Isobutylmethylxanthine, Methylisobutylxanthine |
Anwendung: | Phosphodiesterase inhibitor |
CAS | 28822-58-4 |
MW: | 222.24 D |
ab 34,00 €
Artikelnummer: AG-CR1-3512-M500
Cell permeable protein kinase C (PKC) inhibitor. Inhibits also protein kinase A (PKA).
Schlagworte: | 3-Isobutyl 1-methylxanthine, NSC 165960, EINECS 249-259-3 |
Anwendung: | Phosphodiesterase inhibitor |
CAS | 28822-58-4 |
MW: | 222,3 D |
ab 121,00 €
Artikelnummer: BPS-60110
Active human PDE11A4 (GenBank Accession No. BAB62712), full length with N-terminal GST tag, MW= 131 kDa, expressed in a Baculovirus infected Sf9 cell expression system.
Schlagworte: | cAMP and cGMP phosphodiesterase 11A, Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A, |
Anwendung: | Enzyme kinetics, inhibitor screening |
MW: | 131 kD |
685,00 €
Artikelnummer: Cay26418-1
Quercetin-d3(hydrate) is intended for use as an internal standard for the quantification of quercetin (Cay-10005169) by GC- or LC-MS. Quercetin is an abundant flavonoid that has been isolated from a variety of plants and has diverse biological activities, including antioxidant, anticancer, and anti-inflammatory...
Schlagworte: | 2-(4,5-dihydroxyphenyl-2,3,6-d3)-3,5,7-trihydroxy-4H-1-benzopyran-4-one, hydrate |
Anwendung: | GC-MS, LC-MS, quantification, internal standard, phosphodiesterase inhibitor |
MW: | 305.3 D |
ab 117,00 €
Artikelnummer: ARG10787.50
Protein function: Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides cAMP and cGMP. Catalyzes the hydrolysis of both cAMP and cGMP to 5'-AMP and 5'- GMP, respectively. [The UniProt Consortium]
Schlagworte: | Anti-PDE11A, EC=3.1.4.35, EC=3.1.4.53, Anti-cAMP and cGMP phosphodiesterase 11A, Anti-Dual 3',5'-cyclic-AMP and -GMP... |
Anwendung: | IF, ELISA, ICC, IF, IHC (paraffin), IP, WB, DB |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse, rat |
608,00 €
Artikelnummer: ARG10788.50
Protein function: Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides cAMP and cGMP. Catalyzes the hydrolysis of both cAMP and cGMP to 5'-AMP and 5'- GMP, respectively. [The UniProt Consortium]
Schlagworte: | Anti-PDE11A, EC=3.1.4.35, EC=3.1.4.53, Anti-cAMP and cGMP phosphodiesterase 11A, Anti-Dual 3',5'-cyclic-AMP and -GMP... |
Anwendung: | IF, ELISA, ICC, IF, IHC, IP, WB, DB |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse, rat |
608,00 €
Artikelnummer: ARG10817.50
Protein function: Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides cAMP and cGMP. Catalyzes the hydrolysis of both cAMP and cGMP to 5'-AMP and 5'- GMP, respectively. [The UniProt Consortium]
Schlagworte: | Anti-phospho-PDE11A, EC=3.1.4.35, EC=3.1.4.53, Anti-phospho-cAMP and cGMP phosphodiesterase 11A, Anti-phospho-Dual... |
Anwendung: | ELISA, IP, WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse, rat |
625,00 €
Artikelnummer: ARG10818.50
Protein function: Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides cAMP and cGMP. Catalyzes the hydrolysis of both cAMP and cGMP to 5'-AMP and 5'- GMP, respectively. [The UniProt Consortium]
Schlagworte: | Anti-phospho-PDE11A, EC=3.1.4.35, EC=3.1.4.53, Anti-phospho-cAMP and cGMP phosphodiesterase 11A, Anti-phospho-Dual... |
Anwendung: | IF, ELISA, ICC, IF, IHC, IP, WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse, rat |
625,00 €
Artikelnummer: ARG64245.100
Protein function: Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides cAMP and cGMP. Catalyzes the hydrolysis of both cAMP and cGMP to 5'-AMP and 5'- GMP, respectively. [The UniProt Consortium]
Schlagworte: | Anti-PDE11A, EC=3.1.4.17, EC=3.1.4.35, Anti-cAMP and cGMP phosphodiesterase 11A, Anti-Dual 3',5'-cyclic-AMP and -GMP... |
Anwendung: | ELISA, WB |
Wirt: | Goat |
Spezies-Reaktivität: | human |
822,00 €
Artikelnummer: BPS-27213
IBMX, also known as 1-Methyl-3-Isobutylxanthine and Isobutylmethylxanthine, is a widely-used inhibitor of cAMP and cGMP PDEs. It has been shown that the increase in cellular cAMP and cGMP levels, resulting from the inhibition of PDEs by IBMX, activates cyclicnucleotide-regulated protein kinases. IBMX does not...
Anwendung: | PDE inhibitor |
MW: | 222.3 D |
270,00 €