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Quercetin (hydrate)
Quercetin (hydrate)

Artikelnummer: Cay10005169-5

Quercetin is an abundant flavonoid that has been isolated from a variety of fruits and vegetables and has diverse biological activities, including antioxidant, anticancer, and anti-inflammatory properties. Quercetin (5-100 mg/kg) reduces autophagy, decreases the levels of reactive oxygen species (ROS) and...
Schlagworte: 2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-4H-1-benzopyran-4-one, hydrate
Anwendung: Bioactìve flavonoid
CAS 849061-97-8
MW: 302.2 D
28,00 €
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IBMX
IBMX

Artikelnummer: Cay13347-100

IBMX is a widely-used non-specific inhibitor of cyclic AMP and cyclic GMP phosphodiesterases (PDEs) (IC50 = 19, 50, 18, 13, 32, 7, and 50 µM for PDE1, PDE2, PDE3, PDE4, PDE5, PDE7, and PDE11, respectively). PDE8A, PDE8B, and PDE9 are insensitive to IBMX. By inhibiting PDEs, IBMX increases cellular cAMP and cGMP...
Schlagworte: 1-Methyl-3-Isobutylxanthine, Isobutylmethylxanthine, NSC 165960, SC-2964,...
Anwendung: PDE inhibitor
CAS 28822-58-4
MW: 222.3 D
ab 52,00 €
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IBMX
IBMX

Artikelnummer: TGM-T1713-100mg

Description: IBMX (Methylisobutylxanthine) is a broad-spectrum phosphodiesterase (PDE) inhibitor with inhibitory activity against PDE3, PDE4, and PDE5 (IC50=6.5/26.3/31.7 µM). IBMX enhances the intracellular cAMP level. Target: PDE. Smiles: CC(C)Cn1c2[nH]cnc2c(=O)n(C)c1=O. References: Wei Y, et al. Angiotensin II...
Schlagworte: 3-Isobutyl-1-methylxanthine, 1-Methyl-3-Isobutylxanthine, Isobutylmethylxanthine, Methylisobutylxanthine
Anwendung: Phosphodiesterase inhibitor
CAS 28822-58-4
MW: 222.24 D
ab 34,00 €
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IBMX
IBMX

Artikelnummer: AG-CR1-3512-M500

Cell permeable protein kinase C (PKC) inhibitor. Inhibits also protein kinase A (PKA).
Schlagworte: 3-Isobutyl 1-methylxanthine, NSC 165960, EINECS 249-259-3
Anwendung: Phosphodiesterase inhibitor
CAS 28822-58-4
MW: 222,3 D
ab 121,00 €
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PDE11A4, active human recombinant protein
PDE11A4, active human recombinant protein

Artikelnummer: BPS-60110

Active human PDE11A4 (GenBank Accession No. BAB62712), full length with N-terminal GST tag, MW= 131 kDa, expressed in a Baculovirus infected Sf9 cell expression system.
Schlagworte: cAMP and cGMP phosphodiesterase 11A, Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A,
Anwendung: Enzyme kinetics, inhibitor screening
MW: 131 kD
685,00 €
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Quercetin-d3 (hydrate)
Quercetin-d3 (hydrate)

Artikelnummer: Cay26418-1

Quercetin-d3(hydrate) is intended for use as an internal standard for the quantification of quercetin (Cay-10005169) by GC- or LC-MS. Quercetin is an abundant flavonoid that has been isolated from a variety of plants and has diverse biological activities, including antioxidant, anticancer, and anti-inflammatory...
Schlagworte: 2-(4,5-dihydroxyphenyl-2,3,6-d3)-3,5,7-trihydroxy-4H-1-benzopyran-4-one, hydrate
Anwendung: GC-MS, LC-MS, quantification, internal standard, phosphodiesterase inhibitor
MW: 305.3 D
ab 117,00 €
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Anti-PDE11A
Anti-PDE11A

Artikelnummer: ARG10787.50

Protein function: Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides cAMP and cGMP. Catalyzes the hydrolysis of both cAMP and cGMP to 5'-AMP and 5'- GMP, respectively. [The UniProt Consortium]
Schlagworte: Anti-PDE11A, EC=3.1.4.35, EC=3.1.4.53, Anti-cAMP and cGMP phosphodiesterase 11A, Anti-Dual 3',5'-cyclic-AMP and -GMP...
Anwendung: IF, ELISA, ICC, IF, IHC (paraffin), IP, WB, DB
Wirt: Rabbit
Spezies-Reaktivität: human, mouse, rat
608,00 €
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Anti-PDE11A
Anti-PDE11A

Artikelnummer: ARG10788.50

Protein function: Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides cAMP and cGMP. Catalyzes the hydrolysis of both cAMP and cGMP to 5'-AMP and 5'- GMP, respectively. [The UniProt Consortium]
Schlagworte: Anti-PDE11A, EC=3.1.4.35, EC=3.1.4.53, Anti-cAMP and cGMP phosphodiesterase 11A, Anti-Dual 3',5'-cyclic-AMP and -GMP...
Anwendung: IF, ELISA, ICC, IF, IHC, IP, WB, DB
Wirt: Rabbit
Spezies-Reaktivität: human, mouse, rat
608,00 €
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Anti-phospho-PDE11A (Ser117 / Ser124)
Anti-phospho-PDE11A (Ser117 / Ser124)

Artikelnummer: ARG10817.50

Protein function: Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides cAMP and cGMP. Catalyzes the hydrolysis of both cAMP and cGMP to 5'-AMP and 5'- GMP, respectively. [The UniProt Consortium]
Schlagworte: Anti-phospho-PDE11A, EC=3.1.4.35, EC=3.1.4.53, Anti-phospho-cAMP and cGMP phosphodiesterase 11A, Anti-phospho-Dual...
Anwendung: ELISA, IP, WB
Wirt: Rabbit
Spezies-Reaktivität: human, mouse, rat
625,00 €
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Anti-phospho-PDE11A (Ser117)
Anti-phospho-PDE11A (Ser117)

Artikelnummer: ARG10818.50

Protein function: Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides cAMP and cGMP. Catalyzes the hydrolysis of both cAMP and cGMP to 5'-AMP and 5'- GMP, respectively. [The UniProt Consortium]
Schlagworte: Anti-phospho-PDE11A, EC=3.1.4.35, EC=3.1.4.53, Anti-phospho-cAMP and cGMP phosphodiesterase 11A, Anti-phospho-Dual...
Anwendung: IF, ELISA, ICC, IF, IHC, IP, WB
Wirt: Rabbit
Spezies-Reaktivität: human, mouse, rat
625,00 €
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Anti-PDE11A, Internal
Anti-PDE11A, Internal

Artikelnummer: ARG64245.100

Protein function: Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides cAMP and cGMP. Catalyzes the hydrolysis of both cAMP and cGMP to 5'-AMP and 5'- GMP, respectively. [The UniProt Consortium]
Schlagworte: Anti-PDE11A, EC=3.1.4.17, EC=3.1.4.35, Anti-cAMP and cGMP phosphodiesterase 11A, Anti-Dual 3',5'-cyclic-AMP and -GMP...
Anwendung: ELISA, WB
Wirt: Goat
Spezies-Reaktivität: human
822,00 €
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IBMX
IBMX

Artikelnummer: BPS-27213

IBMX, also known as 1-Methyl-3-Isobutylxanthine and Isobutylmethylxanthine, is a widely-used inhibitor of cAMP and cGMP PDEs. It has been shown that the increase in cellular cAMP and cGMP levels, resulting from the inhibition of PDEs by IBMX, activates cyclicnucleotide-regulated protein kinases. IBMX does not...
Anwendung: PDE inhibitor
MW: 222.3 D
270,00 €
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