Zu "K13241" wurden 133 Artikel gefunden!
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L-NIL (hydrochloride)
Artikelnummer: Cay80310-10
L-NIL is a relatively selective inhibitor of iNOS. It exhibits IC50 values of 0.4-3.3 µM for iNOS as opposed to 8-38 and 17-92 µM for eNOS and nNOS, respectively. L-NIL effectively inhibits iNOS both in vitro and in vivo. L-NIL has been used to demonstrate a critical role for iNOS in the immune response to infection...
| Schlagworte: | N6-(1-iminoethyl)-L-lysine, dihydrochloride |
| Anwendung: | iNOS inhibitor |
| CAS | 159190-45-1 |
| MW: | 260.2 D |
ab 55,00 €
Diphenyleneiodonium (chloride)
Artikelnummer: Cay81050-10
Diphenyleneiodonium (DPI) is an inhibitor of NADPH oxidase (NOX, EC50 = 0.1 µM in HeLa cells). It also inhibits nitric oxide synthase (NOS, IC50 = 0.05 µM in isolated mouse peritoneal macrophages). DPI (10, 50, and 100 µM) induces the production of reactive oxygen species (ROS) in, and apoptosis of, human umbilical...
| Schlagworte: | DPI, dibenziodolium chloride |
| Anwendung: | iNOS inhibitor, eNOS inhibitor |
| CAS | 4673-26-1 |
| MW: | 314.5 D |
ab 61,00 €
L-NIL dihydrochloride
Artikelnummer: TGM-T25749-100mg
Description: L-NIL HCl is a relatively selective iNOS inhibitor (IC50s: 0.4-3.3, 8-38, and 17-92 µM for iNOS, eNOS, and nNOS). L-NIL effectively inhibits iNOS both in vitro and in vivo. L-NIL has been used to demonstrate a critical role for iNOS in the immune response to infection by the protozoan L. major. Target:...
| Schlagworte: | L-NIL HCl, N-Iminoethyl-L-lysine dihydrochloride |
| Anwendung: | iNOS inhibitor |
| CAS | 159190-45-1 |
| MW: | 260.16 D |
ab 98,00 €
1400W dihydrochloride
Artikelnummer: TGM-T3491-10mg
Description: 1400W dihydrochloride (N-(3-(Aminomethyl)benzyl)acetamidine) is a highly effective and specific inhibitor of inducible NOS2 (iNOS). Target: NO Synthase, NOS. Smiles: Cl.Cl.CC(=N)NCc1cccc(CN)c1. References: Garvey EP, et al. J Biol Chem. 199, 272(8):4959-63.
| Schlagworte: | 1400W 2HCl, N-(3-(Aminomethyl)benzyl)acetamidine |
| Anwendung: | iNOS inhibitor |
| CAS | 214358-33-5 |
| MW: | 250.17 D |
ab 43,00 €
NOS-IN-1
Artikelnummer: TGM-T21700-1mg
Description: NOS-IN-1 (2-Imino-4-methylpiperidine acetate) is a potent and orally active inhibitor of NO synthase (NOS) isoforms. NOS-IN-1 exhibits IC50s of 0.1 µM, 0.2 µM, and 1.1µM for human iNOS (hiNOS), hnNOS and heNOS, respectively. Target: NOS. Smiles: CC(CCN1)CC1=N.CC(O)=O. References: R K Webber, et al....
| Schlagworte: | 2-Imino-4-methylpiperidine (acetate) |
| Anwendung: | NOS inhibitor |
| CAS | 165383-72-2 |
| MW: | 172.22 D |
ab 60,00 €
Cindunistat HCl maleate
Artikelnummer: TGM-T30939-25mg
Description: Cindunistat( PHA-728669F, PF-00572986, PHA-84250, SD-6010, and SC-084250) is a potent and oral selective iNOS inhibitor which is expected to be used in patients with symptomatic osteoarthritis of the knee. Target: Others. Smiles:...
| Schlagworte: | SD 6010, PHA 728669F, SD6010 PF-00572986, PHA-728669F, SD-6010, PHA728669F |
| Anwendung: | Targets nitric-oxide synthase, inducible [EC:1.14.13.39] (NOS2) |
| CAS | 753491-31-5 |
| MW: | 591.14 D |
2.421,00 €
FK-330
Artikelnummer: TGM-T31795-100mg
Description: FK-330 (FR-260330) is a novel orally active inducible nitric oxide synthase inhibitor with potential anticancer and antitumor activity that prevents ischemia and reperfusion injury in rat liver transplantation. Target: NOS. Smiles:...
| Schlagworte: | FK330, FK 330, LS-192510, FR-260330 |
| Anwendung: | iNOS inhibitor |
| CAS | 442198-67-6 |
| MW: | 617.02 D |
ab 194,00 €
D-NMMA (acetate)
Artikelnummer: TGM-T37517-100mg
Description: D-NMMA (acetate) can be used in related research in the field of life sciences. Its product number is T37517 and CAS number is 137694-75-8. Target: Others. Smiles: C(C)(O)=O.C([C@H](C(O)=O)N)CCNC(NC)=N
| Anwendung: | Negative control |
| CAS | 137694-75-8 |
| MW: | 248.28 D |
ab 122,00 €
iNOS inhibitor-10
Artikelnummer: TGM-T72638-100mg
Description: iNOS Inhibitor-10, with an IC50 of 65 nM, exhibits antiproliferative effects on triple-negative breast cancer cells [1]. Target: NO Synthase. Smiles: CC1=CC=C(C=C1)S(=O)(=O)NCC2=CC(=CC=C2)CN=C(C3=CC=CC=C3)N
| Anwendung: | iNOS inhibitor |
| CAS | 2918773-63-2 |
| MW: | 393.5 D |
ab 1.520,00 €
2-Iminobiotin
Artikelnummer: TGM-T7206-100mg
Description: 2-Iminobiotin (Guanidinobiotin) is a cyclic guanidino analog of biotin and serves as a reversible inhibitor of inducible nitric oxide synthase (iNOS) and neuronal NOS (nNOS), with Ki values of 21.8 µM for mouse iNOS and 37.5 µM for rat nNOS. Target: NO Synthase, NOS. Smiles:...
| Schlagworte: | 2-IMINOBIOTIN HYDROBROMIDE, Guanidinobiotin |
| Anwendung: | iNOS / nNOS inhibitor |
| CAS | 13395-35-2 |
| MW: | 243.33 D |
ab 77,00 €
2-Iminobiotin hydrobromide
Artikelnummer: TGM-T7206L-10mg
Description: 2-Iminobiotin hydrobromide (Guanidinobiotin) is a cyclic guanidino analog of biotin that acts as a reversible inhibitor of inducible nitric oxide synthase (iNOS) and neuronal NOS (nNOS, Ki of 21.8 and 37.5 µM for mouse iNOS and rat nNOS, respectively). Target: NO Synthase, NOS. Smiles:...
| Schlagworte: | Guanidinobiotin |
| Anwendung: | Guanidine-modified biotin derivative, iNOS and nNOS inhibitor |
| CAS | 76985-52-9 |
| MW: | 324.24 D |
ab 30,00 €
Diphenyleneiodonium chloride
Artikelnummer: TGM-T7191-100mg
Description: Diphenyleneiodonium chloride (DPI)(DPI) is an irreversible inhibitor of iNOS and eNOS (IC50 values of 50 nM and 0.3 µM, respectively),and displays broad-spectrum bactericidal activity. Target: TRP/TRPV Channel, NADPH, Reactive Oxygen Species, NOS. Smiles: [Cl-].[I+]1c2ccccc2-c2ccccc12. References:...
| Schlagworte: | DPI |
| Anwendung: | iNOS inhibitor, eNOS inhibitor |
| CAS | 4673-26-1 |
| MW: | 314.55 D |
ab 40,00 €