Zu "K13129" wurden 56 Artikel gefunden!
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NEU
Anti-SMN1 Recombinant
Artikelnummer: ABS-KC-3061.100
Protein function: The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2,...
| Schlagworte: | Recombinant SMN1 Antibody |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 232,00 €
NEU
Anti-SMN1
Artikelnummer: ABS-KC-4440.100
Protein function: The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2,...
| Schlagworte: | Anti-Survival motor neuron protein, Anti-Component of gems 1, Anti-Gemin-1, SMN1 Antibody |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human, monkey |
ab 232,00 €
SMN1 Protein, Mouse, Recombinant (His & Myc)
Artikelnummer: TGM-TMPH-02920-100ug
Description: SMN1 Protein, Mouse, Recombinant (His & Myc) is expressed in HEK293 mammalian cells with N-10xHis and C-Myc tag. The predicted molecular weight is 35.3 kDa and the accession number is P97801.
| Schlagworte: | Smn1, Survival motor neuron protein |
| MW: | 35.3 kD |
ab 464,00 €
Risdiplam
Artikelnummer: TGM-T16757-100mg
Description: Risdiplam (RO7034067) (RG7916) is orally administered. Risdiplam is a centrally and peripherally distributed SMN2 pre-mRNA splicing modifier which increases survival motor neuron (SMN) protein levels[1]. Target: DNA/RNA Synthesis. Smiles: Cc1cn2nc(cc(C)c2n1)-c1cc(=O)n2cc(ccc2n1)N1CCNC2(CC2)C1....
| Schlagworte: | RO7034067, RG7916 |
| Anwendung: | Targets survival motor neuron protein (SMN) |
| CAS | 1825352-65-5 |
| MW: | 401.46 D |
ab 55,00 €
Cuspin-1
Artikelnummer: TGM-T35594-10mg
Description: The Survival of Motor Neurons (SMN) protein participates in RNA splicing. Decreases in SMN, typically a consequence of defects in the smn1 gene, result in the death of motor neurons and lead to the neurodegenerative disease, spinal muscular atrophy (SMA). Cuspin-1 is a small molecule upregulator of SMN...
| Anwendung: | SMN upregulator |
| CAS | 337932-29-3 |
| MW: | 276.13 D |
ab 142,00 €
Nusinersen
Artikelnummer: TGM-T38656-10mg
Description: Nusinersen, an antisense oligonucleotide drug, modifies the pre-messenger RNA (pre-mRNA) splicing of the SMN2 gene, thereby enhancing the production of the full-length Survival Motor Neuron (SMN) protein. Target: Others. References: Richard S Finkel, et al. Nusinersen versus Sham Control in...
| Anwendung: | Targets survival motor neuron protein (SMN) |
| CAS | 1258984-36-9 |
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Branaplam
Artikelnummer: TGM-T4641-100mg
Description: Branaplam (LMI 070) is a highly potent, selective and orally active small molecule SMN2 splicing modulator. Target: Potassium Channel, Others, DNA/RNA Synthesis. Smiles: CC1(C)CC(CC(C)(C)N1)Oc1ccc(nn1)-c1ccc(cc1O)-c1cn[nH]c1. References: Palacino J, et al. SMN2 splice modulators enhance U1-pre-mRNA...
| Schlagworte: | LMI 070, NVS-SM1 |
| Anwendung: | Targets survival motor neuron protein (SMN) |
| CAS | 1562338-42-4 |
| MW: | 393.48 D |
ab 42,00 €
Branaplam hydrochloride
Artikelnummer: TGM-T62381-2mg
Description: Branaplam (LMI070, NVS-SM1) hydrochloride is a selective, orally active SMN2 splicing modulator that acts on SMN (EC50: 20 nM) and inhibits hERG (IC50: 6.3 µM). In a mouse model of severe spinal muscular atrophy (SMA), Branaplam hydrochloride increased full-length SMN protein and improved survival....
| Anwendung: | Targets survival motor neuron protein (SMN) |
| CAS | 1562338-39-9 |
| MW: | 429.95 D |
54,00 €
Anti-SMN1
Artikelnummer: CSB-PA135133.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: SMN1. Antigen Species: Human
| Schlagworte: | Anti-SMN, Anti-SMN2, Anti-SMNC, Anti-SMN1, Anti-Gemin-1, Anti-Component of gems 1, Anti-Survival motor neuron protein,... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 167,00 €
Anti-SMN1
Artikelnummer: CSB-PA678622.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: SMN1. Antigen Species: Human
| Schlagworte: | Anti-SMN, Anti-SMN2, Anti-SMNC, Anti-SMN1, Anti-Gemin-1, Anti-Component of gems 1, Anti-Survival motor neuron protein,... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 167,00 €
Survival motor neuron protein (Smn1), mouse, recombinant
Artikelnummer: CSB-BP021838MO.1
Organism: Mus musculus (Mouse). Source: Baculovirus. Expression Region: 1-288aa. Protein Length: Full Length. Tag Info: N-terminal 10xHis-tagged and C-terminal Myc-tagged. Target Protein Sequence: MAMGSGGAGS EQEDTVLFRR GTGQSDDSDI WDDTALIKAY DKAVASFKHA LKNGDICETP DKPKGTARRK PAKKNKSQKK NATTPLKQWK VGDKCSAVWS EDGCIYPATI...
| Schlagworte: | Smn, Smn1, Survival motor neuron protein, Recombinant Mouse Survival motor neuron protein (Smn1) |
| Anwendung: | Activity not tested |
| Exprimiert in: | Insect cells |
| Ursprungsart: | mouse |
| MW: | 35.3 kD |
ab 489,00 €
Survival motor neuron protein (SMN1), human, recombinant
Artikelnummer: CSB-EP614982HU.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 2-294aa. Protein Length: Full Length of Mature Protein. Tag Info: N-terminal 10xHis-tagged and C-terminal Myc-tagged. Target Protein Sequence: AMSSGGSGGG VPEQEDSVLF RRGTGQSDDS DIWDDTALIK AYDKAVASFK HALKNGDICE TSGKPKTTPK RKPAKKNKSQ KKNTAASLQQ...
| Schlagworte: | SMN, SMN2, SMNC, SMN1, Gemin-1, Component of gems 1, Survival motor neuron protein, Recombinant Human Survival motor... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 36.7 kD |
ab 292,00 €