Zu "K12319" wurden 36 Artikel gefunden!
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Anti-GUCY1B1
Artikelnummer: ATA-HPA077706.100
Polyclonal Antibody against Human GUCY1B1, Gene description: guanylate cyclase 1 soluble subunit beta 1, Alternative Gene Names: GC-S-beta-1, GC-SB3, GUC1B3, GUCY1B3, Validated applications: ICC, Uniprot ID: Q02153, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C. Protein...
| Schlagworte: | Anti-GUC1B3, Anti-GCS-beta-3, Anti-GCS-beta-1, Anti-Soluble guanylate cyclase small subunit, Anti-Guanylate cyclase... |
| Anwendung: | ICC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
477,00 €
ODQ
Artikelnummer: Cay81410-5
ODQ is a highly selective, irreversible, heme-site inhibitor of soluble guanylyl cyclase. The binding of ODQ is competitive with NO. The inhibition of soluble guanylyl cyclase is time dependent with complete inactivation in 10 minutes at 0.3 µM ODQ.Formal Name: 1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one. CAS...
| Schlagworte: | 1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one |
| Anwendung: | Guanylyl cyclase inhibitor |
| CAS | 41443-28-1 |
| MW: | 187.2 D |
ab 49,00 €
Anti-Guanylate Cyclase beta1 subunit (soluble)
Artikelnummer: Cay160897-1
Soluble guanylate cyclase (sGC) is a heterodimeric hemoprotein and nitric oxide (NO) sensor composed of two subunits, alpha1 and beta1. The approximately 70 kDa sGC beta1 subunit is encoded by GUCY1B3 in humans, ubiquitously expressed, and localized to the cytosol. The sGC histidine residue at position 105 is...
| Schlagworte: | Anti-Guc1b3, Anti-Gucy1b1, Anti-GCS-beta-1, Anti-GCS-beta-3, Anti-GCS-beta-1, Anti-GCS-beta-3, Anti-Soluble guanylate... |
| Anwendung: | IHC, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | rat |
431,00 €
Anti-GUCY1B3
Artikelnummer: CSB-PA002672.50
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-GUC1B3, Anti-GCS-beta-1, Anti-GCS-beta-3, Anti-Soluble guanylate cyclase small subunit, Anti-Guanylate cyclase... |
| Anwendung: | ELISA, WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
126,00 €
Anti-GUCY1B3
Artikelnummer: CSB-PA214476.100
Host Species: Rabbit. Isotype: IgG. Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by...
| Schlagworte: | Anti-GUC1B3, Anti-GCS-beta-1, Anti-GCS-beta-3, Anti-Soluble guanylate cyclase small subunit, Anti-Guanylate cyclase... |
| Anwendung: | ELISA, WB, IHC, IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
283,00 €
YC-1
Artikelnummer: Cay81560-5
YC-1 is an nitric oxide (NO)-independent activator of soluble guanylyl cyclase. It inhibits collagen (10 µg/ml) and thrombin (0.1 U/ml) induced platelet aggregation with IC50 values of 11.7-14.6 and 57.3-59.3 µM, respectively. In the absence of NO or carbon monoxide (CO), 200 µM YC-1 increases the activity of...
| Schlagworte: | 5-[1-(phenylmethyl)-1H-indazol-3-yl]-2-furanmethanol |
| Anwendung: | Platelet aggregation inhibitor |
| CAS | 170632-47-0 |
| MW: | 304.3 D |
ab 25,00 €
Riociguat
Artikelnummer: Cay9000554-5
Riociguat is a stimulator of soluble guanylate cyclase (sGC)., It stimulates recombinant sGC in a concentration-dependent manner in vitro by up to 73-fold when used at a concentration of 100 µM or by up to 112-fold when used in combination with the nitric oxide (NO) donor DEA NONOate (Cay-82100). It has no effect on...
| Schlagworte: | BAY 63-2521, N-[4,6-diamino-2-[1-[(2-fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridin-3-yl]-5-pyrimidinyl]-N-methyl-carbamic... |
| Anwendung: | Soluble guanylate cyclase activator |
| CAS | 625115-55-1 |
| MW: | 422.4 D |
ab 116,00 €
Ataciguat
Artikelnummer: Cay16371-5
Soluble guanylate cyclase (sGC) is the primary cellular receptor for NO. NO binds and activates a heme group in sGC, initiating the conversion of GTP to the second messenger cGMP. cGMP subsequently mediates a number of signaling cascades leading to vasorelaxation and inhibiting smooth muscle proliferation, leukocyte...
| Schlagworte: | HMR 1766, 5-chloro-2-[[(5-chloro-2-thienyl)sulfonyl]amino]-N-[4-(4-morpholinylsulfonyl)phenyl]-benzamide |
| Anwendung: | sGC, oxidized, heme-free, form, activator |
| CAS | 254877-67-3 |
| MW: | 576.5 D |
ab 111,00 €
Cinaciguat (hydrochloride)
Artikelnummer: Cay17468-500
Soluble guanylate cyclase (sGC) is the primary cellular receptor for NO. NO binds and activates a heme group in sGC, initiating the conversion of GTP to the second messenger cGMP. cGMP subsequently mediates a number of signaling cascades leading to vasorelaxation and inhibiting smooth muscle proliferation, leukocyte...
| Schlagworte: | BAY 58-2667, 4-[[(4-carboxybutyl)[2-[2-[[4-(2-phenylethyl)phenyl]methoxy]phenyl]ethyl]amino]methyl]-benzoic acid,... |
| Anwendung: | Soluble guanylate cyclase activator |
| CAS | 646995-35-9 |
| MW: | 602.2 D |
ab 78,00 €
NS 2028
Artikelnummer: Cay81600-5
NS 2028 is a specific inhibitor of soluble guanylyl cyclase. It inhibits purified bovine lung guanylyl cyclase in a concentration dependent and irreversible manner with IC50 values of 30 and 200 nM for basal and NO-stimulated enzymes, respectively. S-nitroso-glutathione-enhanced guanylyl cyclase activity in mouse...
| Schlagworte: | 8-bromo-4H-2,5-dioxa-3,9b-diaza-cyclopenta[a]naphthalen-1-one |
| Anwendung: | Guanylyl cyclase inhibitor |
| CAS | 204326-43-2 |
| MW: | 269.1 D |
ab 65,00 €
Anti-Guanylyl Cyclase beta
Artikelnummer: ARG10821.50
Protein function: Mediates responses to nitric oxide (NO) by catalyzing the biosynthesis of the signaling molecule cGMP. [The UniProt Consortium]
| Schlagworte: | Anti-Guc1b3, Anti-Gucy1b3, Anti-GCS-beta-1, Anti-GCS-beta-3, Anti-Soluble guanylate cyclase small subunit, Anti-Guanylate... |
| Anwendung: | IF, ELISA, ICC, IF, IHC (paraffin), IP, WB, DB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | bovine, human, mouse, swine, rat |
608,00 €