Zu "K11987" wurden 329 Artikel gefunden!
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COX Fluorescent Inhibitor Screening Assay Kit
Artikelnummer: Cay700100-192
Cyclooxygenase (COX, also called Prostaglandin H Synthase or PGHS) is a bifunctional enzyme exhibiting both COX and peroxidase activities. The COX component converts arachidonic acid to a hydroperoxy endoperoxide (PGG2), and the peroxidase component reduces the endoperoxide to the corresponding alcohol (PGH2), the...
| Schlagworte: | Cyclooxygenase Fluorescent Inhibitor Screening Assay Kit |
| Anwendung: | COX inhibitor screening |
915,00 €
COX-2 (human) Inhibitor Screening Assay Kit
Artikelnummer: Cay701080-96
The COX-2 (human) Inhibitor Screening Assay directly measures PGF2alpha by stannous chloride (SnCl2) reduction of COX-derived PGH2 produced in the COX reaction. The prostanoid product is quantified via ELISA using an antiserum specific to PGF2alpha. This assay includes recombinant human COX-2 and is an excellent...
| Schlagworte: | Cyclooxygenase 2 |
| Anwendung: | Inhibitor screening |
597,00 €
Anti-COX-2 (Clone CX229)
Artikelnummer: Cay160112-1
Cyclooxygenase 2 (COX-2) is a bifunctional enzyme that exhibits both COX and peroxidase activities and catalyzes the first step in the biosynthesis of prostaglandins, thromboxanes, and prostacyclins. The COX component converts arachidonic acid (Cay-90010, Cay-90010.1, Cay-10006607) to the hydroperoxy endoperoxide...
| Schlagworte: | Cyclooxygenase 2, PGHS-2, Prostaglandin H Synthase 2 |
| Anwendung: | IHC, WB |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human, ovine, monkey |
431,00 €
NS 398
Artikelnummer: Cay70590-5
NS 398 is a selective inhibitor of cyclooxygenase-2 (COX-2). The IC50 values for human recombinant COX-1 and -2 are 75 and 1.77 µM, respectively. The IC50 values for ovine COX-1 and -2 are 220 and 0.15 µM, respectively.Formal Name: N-[2-(cyclohexyloxy)-4-nitrophenyl]-methanesulfonamide. CAS Number: 123653-11-2....
| Schlagworte: | N-[2-(cyclohexyloxy)-4-nitrophenyl]-methanesulfonamide |
| Anwendung: | COX-2 inhibitor |
| CAS | 123653-11-2 |
| MW: | 314.4 D |
ab 66,00 €
Celecoxib
Artikelnummer: LKT-C1644.1
Celecoxib is a selective COX 2 inhibitor.
| Anwendung: | COX-2 inhibitor |
| CAS | 169590-42-5 |
| MW: | 381,37 D |
ab 164,00 €
COX-2 (human, recombinant)
Artikelnummer: Cay60122-5
Cyclooxygenase 2 (COX-2) is a bifunctional enzyme that exhibits both COX and peroxidase activities and catalyzes the first step in the biosynthesis of prostaglandins, thromboxanes, and prostacyclins. The COX component converts arachidonic acid to the hydroperoxy endoperoxide prostaglandin G2 (PGG2, Cay-17010), and...
| Schlagworte: | PHS II, PGHS-2, PHS II, PGHS-2, PGH synthase 2, PGH synthase 2, Prostaglandin H2 synthase 2, Prostaglandin H2 synthase 2,... |
| Anwendung: | Enzyme activity |
1.123,00 €
Firocoxib
Artikelnummer: TGM-T7596-100mg
Description: Firocoxib (ML 1785713) is a selective non-steroidal inhibitor of cyclooxygenase-2 (COX-2) with an IC50 of 0.13 µM, used for its anti-inflammatory properties in dogs and horses. Target: COX. Smiles: O(CC1CC1)C2=C(C(C)(C)OC2=O)C3=CC=C(S(C)(=O)=O)C=C3. References: Stock ML, et al. Pharmacokinetics of...
| Schlagworte: | ML 1785713 |
| Anwendung: | Targets prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1] (PTGS2, COX2) |
| CAS | 189954-96-9 |
| MW: | 336.4 D |
ab 34,00 €
Mavacoxib
Artikelnummer: TGM-T7670-100mg
Description: Mavacoxib is a selective inhibitor of cyclooxygenase-2 (COX-2) ,with Anti-Tumour activity. Target: COX. Smiles: NS(=O)(=O)c1ccc(cc1)-n1nc(cc1-c1ccc(F)cc1)C(F)(F)F. References: Emma A Hurst, Lisa Y Pang, David J Argyle .The Selective cyclooxygenase-2 Inhibitor Mavacoxib (Trocoxil) Exerts Anti-Tumour...
| Anwendung: | Targets prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1] (PTGS2, COX2) |
| CAS | 170569-88-7 |
| MW: | 385.34 D |
ab 31,00 €
Losartan Carboxaldehyde
Artikelnummer: TGM-T7838-100mg
Description: Losartan Carboxaldehyde is an endothelial cyclooxygenase (COX)-2 inhibitor. Target: COX. Smiles: CCCCc1nc(Cl)c(C=O)n1Cc1ccc(cc1)-c1ccccc1-c1nn[nH]n1. References: Kramer, C. Angiotensin II Receptor-Independent Antiinflammatory and Antiaggregatory Properties of Losartan: Role of the Active Metabolite...
| Anwendung: | COX-2 expression inhibitor |
| CAS | 114798-36-6 |
| MW: | 420.89 D |
ab 31,00 €
SC-236
Artikelnummer: TGM-T8505-100mg
Description: SC-236 (Sc 236) is an orally active and selective inhibitor of COX-2 (IC50 of 0.005 µM and 17.8 µM for COX-2 and COX-1, respectively). Target: Apoptosis, COX, PPAR. Smiles: NS(=O)(=O)c1ccc(cc1)-n1nc(cc1-c1ccc(Cl)cc1)C(F)(F)F. References: Kim S J , Jeong H J , Moon P D , et al. The COX-2 inhibitor...
| Schlagworte: | Sc 236 |
| Anwendung: | COX-2 inhibitor |
| CAS | 170569-86-5 |
| MW: | 401.79 D |
ab 31,00 €
Salicylic Acid-d4
Artikelnummer: TGM-TMIH-0513-1mg
Description: Salicylic Acid-d4 is a deuterated compound of Salicylic Acid. Smiles: [2H]C1=C([2H])C(O)=C(C([2H])=C1[2H])C(O)=O
| Anwendung: | GC-MS, LC-MS internal standard, quantification, active metabolite |
| CAS | 78646-17-0 |
| MW: | 142.15 D |
ab 42,00 €
COX-2 Protein, Human, Recombinant (His)
Artikelnummer: TGM-TMPY-01736-100ug
Description: PTGS2, also known as COX-2, is s component of Prostaglandin-endoperoxide synthase (PTGS). PTGS, also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2,...
| Schlagworte: | prostaglandin-endoperoxide synthase 2, GRIPGHS, COX-2, PGHS-2, hCox-2, PHS-2, PGG/HS, COX2 |
| MW: | 68.5 kD |
ab 385,00 €