Zu "K11839" wurden 24 Artikel gefunden!
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NEU
DUB-IN-3
Artikelnummer: Cay41594-10
DUB-IN-3 is an inhibitor of ubiquitin-specific protease 8 (USP8, IC50 = 0.56 µM). It is selective for USP8 over USP7 (IC50 = >100 µM). DUB-IN-3 is also an inhibitor of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) papain-like protease (PLpro) when Z-LRGG-AMC is used as a substrate (IC50 = 12.5 µM) but...
| Schlagworte: | Deubiquitinase Inhibitor 3, Deubiquitinase-IN-3, DUBs Inhibitor 3, DUBs-IN-3, HBX 90397,... |
| Anwendung: | USB8 inhibitor |
| CAS | 924296-17-3 |
| MW: | 287.3 D |
ab 431,00 €
NEU
USP8-IN-1
Artikelnummer: Cay41598-1
USP8-IN-1 is an inhibitor of ubiquitin-specific protease 8 (USP8, IC50 = 2.6 µM). It is selective for USP8 over USP7 (IC50 = >20 µM). USP8-IN-1 inhibits colony formation by H1975 non-small cell lung cancer (NSCLC) cells (IC50 = 30.8 µM).Formal Name:...
| Schlagworte: | DC-U43-10, Ubiquitin-specific Protease 8 Inhibitor 1, USP8 Inhibitor 1,... |
| Anwendung: | USP8 inhibitor |
| CAS | 2477650-96-5 |
| MW: | 387.5 D |
ab 67,00 €
NEU
USP8-IN-2
Artikelnummer: Cay41599-1
USP8-IN-2 is an inhibitor of ubiquitin-specific protease 8 (USP8, IC50 = 6 µM).Formal Name: N-(5-chloro-2-methoxyphenyl)-N'-[1-[6-(trifluoromethyl)-2-pyridinyl]-4-piperidinyl]-thiourea. CAS Number: 2477651-11-7. Synonyms: Ubiquitin-specific Protease 8-IN-2, Ubiquitin-specific Protease 8 Inhibitor 2, USP Inhibitor 2....
| Schlagworte: | Ubiquitin-specific Protease 8 Inhibitor 2, Ubiquitin-specific Protease 8-IN-2, USP Inhibitor 2,... |
| Anwendung: | USP8 inhibitor |
| CAS | 2477651-11-7 |
| MW: | 444.9 D |
ab 73,00 €
NEU
USP8-IN-3
Artikelnummer: Cay41600-10
USP8-IN-3 is an inhibitor of ubiquitin-specific protease 8 (USP8, IC50 = 4 µM). It inhibits the growth of H1975 non-small cell lung cancer (NSCLC) and GH3 rat pituitary cells (GI50s = 6.01 and 37.03 µM).Formal Name: N-(4-nitrophenyl)-N'-[1-[6-(trifluoromethyl)-2-pyridinyl]-4-piperidinyl]-thiourea. CAS Number:...
| Schlagworte: | Ubiquitin-specific Protease 8 Inhibitor 3, Ubiquitin-specific Protease 8-IN-3, USP 8 Inhibitor 3,... |
| Anwendung: | USP8 inhibitor |
| CAS | 2477651-10-6 |
| MW: | 425.4 D |
ab 120,00 €
NEU
DUB-IN-1
Artikelnummer: Cay41737-10
DUB-IN-1 is an inhibitor of ubiquitin-specific protease 8 (USP8, IC50 = 0.85 µM). It is selective for USP8 over USP7 (IC50 = >100 µM). It inhibits the proliferation of LN-229, U87MG, and T98G glioblastoma cells when used at concentrations ranging from 200 to 800 nM. DUB-IN-1 (500 and 800 nM) reduces the migration...
| Schlagworte: | Deubiquitinase Inhibitor 1, Deubiquitinase-IN-1, DUB Inhibitor 1, DUBs Inhibitor 1, DUBs-IN-1, 9-[(phenylmethoxy)... |
| Anwendung: | USP8 inhibitor |
| CAS | 924296-18-4 |
| MW: | 337.3 D |
ab 132,00 €
Ubiquitin Isopeptidase Inhibitor I, G5
Artikelnummer: TGM-T17192-100mg
Description: Ubiquitin Isopeptidase Inhibitor I, G5 is a caspase-independent inducer of cell necrosis that induces cell death via the death receptor pathway (IC50 of 1.76 and 1.6 µM in E1A and E1A/C9DN cells, respectively). Target: Apoptosis. Smiles:...
| Schlagworte: | NSC144303 |
| Anwendung: | Ubiquitin Isopeptidase inhibitor |
| CAS | 108477-18-5 |
| MW: | 414.39 D |
ab 73,00 €
Anti-USP8
Artikelnummer: A302-929A
Protein function: Hydrolase that can remove conjugated ubiquitin from proteins and therefore plays an important regulatory role at the level of protein turnover by preventing degradation. Converts both 'Lys-48' an 'Lys-63'-linked ubiquitin chains. Catalytic activity is enhanced in the M phase. Involved in cell...
| Schlagworte: | Anti-USP8, Anti-hUBPy, Anti-KIAA0055, Anti-Ubiquitin thioesterase 8, Anti-Ubiquitin isopeptidase Y, Anti-Deubiquitinating... |
| Anwendung: | WB, IP, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 164,00 €
Anti-USP8
Artikelnummer: A302-930A-T
Protein function: Hydrolase that can remove conjugated ubiquitin from proteins and therefore plays an important regulatory role at the level of protein turnover by preventing degradation. Converts both 'Lys-48' an 'Lys-63'-linked ubiquitin chains. Catalytic activity is enhanced in the M phase. Involved in cell...
| Schlagworte: | Anti-USP8, Anti-hUBPy, Anti-KIAA0055, Anti-Ubiquitin thioesterase 8, Anti-Ubiquitin isopeptidase Y, Anti-Deubiquitinating... |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 164,00 €
USP8 (UBPY), active human recombinant protein, N-terminal...
Artikelnummer: BPS-80358
Human USP8 (Ubiquitin-Specific Protease 8) or UBPY, GenBank Accession No. NM_005154, amino-acids 2-1118(end) with an N-terminal FLAG-tag, MW=128 kDa, expressed in a baculovirus-infected Sf9 cell expression system.
| Schlagworte: | hUBPy, KIAA0055, Ubiquitin isopeptidase Y, Ubiquitin thioesterase 8, Deubiquitinating enzyme 8, Ubiquitin... |
| Anwendung: | Enzyme kinetics, inhibitor screening, selectivity profiling |
| Exprimiert in: | Baculovirus |
| Ursprungsart: | human |
| MW: | 128 kD |
628,00 €
Anti-USP8
Artikelnummer: E-AB-61479.120
This gene encodes a protein that belongs to the ubiquitin-specific processing protease family of proteins. The encoded protein is thought to regulate the morphology of the endosome by ubiquitination of proteins on this organelle and is involved in cargo sorting and membrane trafficking at the early endosome stage....
| Schlagworte: | Anti-hUBPy, Anti-KIAA0055, Anti-Ubiquitin thioesterase 8, Anti-Ubiquitin isopeptidase Y, Anti-Deubiquitinating enzyme 8,... |
| Anwendung: | WB, IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 198,00 €
-30 %
Rabattaktion
Anti-USP8 / UBPY
Artikelnummer: ARG59799.100
Protein function: Hydrolase that can remove conjugated ubiquitin from proteins and therefore plays an important regulatory role at the level of protein turnover by preventing degradation. Converts both 'Lys-48' an 'Lys-63'-linked ubiquitin chains. Catalytic activity is enhanced in the M phase. Involved in cell...
| Schlagworte: | Anti-hUBPy, Anti-KIAA0055, Anti-Ubiquitin thioesterase 8, Anti-Ubiquitin isopeptidase Y, Anti-Deubiquitinating enzyme 8,... |
| Anwendung: | ICC, IF, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
624,00 €
436,80 €
Anti-USP8
Artikelnummer: ATA-HPA050215.100
Protein function: Hydrolase that can remove conjugated ubiquitin from proteins and therefore plays an important regulatory role at the level of protein turnover by preventing degradation. Converts both 'Lys-48' an 'Lys-63'-linked ubiquitin chains. Catalytic activity is enhanced in the M phase. Involved in cell...
| Schlagworte: | Anti-hUBPy, Anti-KIAA0055, Anti-Ubiquitin thioesterase 8, Anti-Ubiquitin isopeptidase Y, Anti-Deubiquitinating enzyme 8,... |
| Anwendung: | ICC, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 335,00 €