Zu "K11757" wurden 23 Artikel gefunden!
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ACBI1
Artikelnummer: TGM-T17350-100mg
Description: ACBI1 is a potent PROTAC degrader of BAF ATPase subunits SMARCA2 and SMARCA4, also degrades the polybromo-associated BAF (PBAF) complex member PBRM1, with DC50s of 6 nM, 11 nM and 32 nM for SMARCA2, SMARCA4 and PBRM1 in MV-4-11 cells, respectively. ACBI1 is composed of a bromodomain ligand, a linker,...
| Anwendung: | PROTAC (BRM/BRG1/PBRM1 degradation) |
| CAS | 2375564-55-7 |
| MW: | 936.1 D |
ab 98,00 €
SGC-SMARCA-BRDVIII
Artikelnummer: TGM-T9568-100mg
Description: SGC-SMARCA-BRDVIII is a potent and selective inhibitor of SMARCA2, SMARCA4, PB1(2), PB1(3), and PB1(5) with Kds of 35 nM, 36 nM, 3.7 µM, 2.0 µM, and 13 nM, respectively. Target: Epigenetic Reader Domain. Smiles: CC(C)(C)OC(=O)N1CCN(CC1)c1cc(nnc1N)-c1ccccc1O. References: Wanior M, et, al. Pan-SMARCA/PB1...
| Anwendung: | Pan-family VIII BRD inhibitor |
| CAS | 1997319-84-2 |
| MW: | 371.43 D |
ab 40,00 €
Anti-PBRM1
Artikelnummer: A301-591A
Protein function: Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Required for the stability of the SWI/SNF chromatin remodeling complex SWI/SNF-B (PBAF). Acts as a negative regulator of cell proliferation. [The UniProt Consortium]
| Schlagworte: | Anti-hPB1, Anti-PBRM1, Anti-BAF180, Anti-Polybromo-1D, Anti-Protein polybromo-1, Anti-BRG1-associated factor 180 |
| Anwendung: | WB, IP, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 178,00 €
Anti-PBRM1
Artikelnummer: A301-590A
Protein function: Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Required for the stability of the SWI/SNF chromatin remodeling complex SWI/SNF-B (PBAF). Acts as a negative regulator of cell proliferation. [The UniProt Consortium]
| Schlagworte: | Anti-hPB1, Anti-PBRM1, Anti-BAF180, Anti-Polybromo-1D, Anti-Protein polybromo-1, Anti-BRG1-associated factor 180 |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 178,00 €
Anti-PBRM1 Recombinant Monoclonal
Artikelnummer: A700-019
Protein function: Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Required for the stability of the SWI/SNF chromatin remodeling complex SWI/SNF-B (PBAF). Acts as a negative regulator of cell proliferation. [The UniProt Consortium]
| Schlagworte: | Anti-hPB1, Anti-PBRM1, Anti-BAF180, Anti-Polybromo-1D, Anti-Protein polybromo-1, Anti-BRG1-associated factor 180 |
| Anwendung: | WB, IP, IHC, ICC, IHC-IF, FC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 185,00 €
PB1 (528-618), human recombinant protein, His-tag
Artikelnummer: BPS-31122
Human polybromo 1 (PB1), also known as PBRM1 and BRG1-associated factor 180, variant 2, (GenBank Accession No. NM_018313), amino-acids 528 ? 618 with N-terminal His-tag, MW = 11.7 kDa, expressed in an E. coli cell expression system.
| Schlagworte: | hPB1, PBRM1, BAF180, Polybromo-1D, Protein polybromo-1, BRG1-associated factor 180, |
| Anwendung: | BRD binding assays, inhibitor screening, selectivity profiling |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 11.7 kD |
461,00 €
PB1 (BD6), Human Recombinant Protein, His-tag
Artikelnummer: BPS-31133
Human polybromo 1 (PB1), also known as PBRM1 and BRG1-associated factor 180, variant 2, (GenBank Accession No. NM_018313), amino-acids 782-872 with N-terminal His-tag, MW = 12 kDa, expressed in an E. coli expression system.
| Schlagworte: | hPB1, PBRM1, BAF180, Polybromo-1D, Protein polybromo-1, BRG1-associated factor 180, |
| Anwendung: | Binding assays, screening inhibitors, selectivity profiling |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 12 kD |
461,00 €
Anti-PBRM1 / Baf180
Artikelnummer: ARG41551.100
Protein function: Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Required for the stability of the SWI/SNF chromatin remodeling complex SWI/SNF-B (PBAF). Acts as a negative regulator of cell proliferation. [The UniProt Consortium]
| Schlagworte: | Anti-hPB1, Anti-PBRM1, Anti-BAF180, Anti-Polybromo-1D, Anti-Protein polybromo-1, Anti-BRG1-associated factor 180 |
| Anwendung: | FC, ICC, IF, IHC (paraffin), WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
658,00 €
Anti-PBRM1 / Baf180
Artikelnummer: ARG41585.100
Protein function: Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Required for the stability of the SWI/SNF chromatin remodeling complex SWI/SNF-B (PBAF). Acts as a negative regulator of cell proliferation. [The UniProt Consortium]
| Schlagworte: | Anti-hPB1, Anti-PBRM1, Anti-BAF180, Anti-Polybromo-1D, Anti-Protein polybromo-1, Anti-BRG1-associated factor 180 |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
658,00 €
Anti-PBRM1
Artikelnummer: ATA-HPA015629.100
Protein function: Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Required for the stability of the SWI/SNF chromatin remodeling complex SWI/SNF-B (PBAF). Acts as a negative regulator of cell proliferation. [The UniProt...
| Schlagworte: | Anti-hPB1, Anti-PBRM1, Anti-BAF180, Anti-Polybromo-1D, Anti-Protein polybromo-1, Anti-BRG1-associated factor 180 |
| Anwendung: | IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 358,00 €
Anti-PBRM1
Artikelnummer: ATA-HPA059373.100
Protein function: Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Required for the stability of the SWI/SNF chromatin remodeling complex SWI/SNF-B (PBAF). Acts as a negative regulator of cell proliferation. [The UniProt...
| Schlagworte: | Anti-hPB1, Anti-PBRM1, Anti-BAF180, Anti-Polybromo-1D, Anti-Protein polybromo-1, Anti-BRG1-associated factor 180 |
| Anwendung: | WB, ICC, ChIP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 239,00 €
Anti-PBRM1, clone CL0331
Artikelnummer: ATA-AMAb90690.100
Protein function: Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Required for the stability of the SWI/SNF chromatin remodeling complex SWI/SNF-B (PBAF). Acts as a negative regulator of cell proliferation. [The UniProt...
| Schlagworte: | Anti-hPB1, Anti-PBRM1, Anti-BAF180, Anti-Polybromo-1D, Anti-Protein polybromo-1, Anti-BRG1-associated factor 180 |
| Anwendung: | WB, IHC |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
ab 320,00 €