Zu "K11722" wurden 152 Artikel gefunden!
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Anti-BRD4
Artikelnummer: A301-985A100
Protein function: Chromatin reader protein that recognizes and binds acetylated histones and plays a key role in transmission of epigenetic memory across cell divisions and transcription regulation. Remains associated with acetylated chromatin throughout the entire cell cycle and provides epigenetic memory for...
| Schlagworte: | Anti-BRD4, Anti-HUNK1, Anti-Protein HUNK1, Anti-Bromodomain-containing protein 4 |
| Anwendung: | WB, IP, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
1.169,00 €
Anti-BRD4
Artikelnummer: A301-985A50
Protein function: Chromatin reader protein that recognizes and binds acetylated histones and plays a key role in transmission of epigenetic memory across cell divisions and transcription regulation. Remains associated with acetylated chromatin throughout the entire cell cycle and provides epigenetic memory for...
| Schlagworte: | Anti-BRD4, Anti-HUNK1, Anti-Protein HUNK1, Anti-Bromodomain-containing protein 4 |
| Anwendung: | WB, IP, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
668,00 €
(+)-JQ1
Artikelnummer: Cay11187-5
The bromodomain and extra terminal domain (BET) family of proteins, including BRD2, BRD3, and BRD4, play a key role in many cellular processes, including inflammatory gene expression, mitosis, and viral/host interaction by controlling the assembly of histone acetylation-dependent chromatin complexes. JQ1 displaces...
| Schlagworte: | (6S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetic acid,... |
| Anwendung: | BRD4 inhibitor |
| CAS | 1268524-70-4 |
| MW: | 457 D |
ab 38,00 €
Bromodomain-containing protein 4 (BRD4), partial,...
Artikelnummer: CSB-YP002802HU3.1
Organism: Homo sapiens (Human). Source: Yeast. Expression Region: 342-460aa. Protein Length: Partial. Tag Info: N-terminal 6xHis-tagged. Target Protein Sequence: PAPEKSSKVS EQLKCCSGIL KEMFAKKHAA YAWPFYKPVD VEALGLHDYC DIIKHPMDMS TIKSKLEARE YRDAQEFGAD VRLMFSNCYK YNPPDHEVVA MARKLQDVFE MRFAKMPDE. Purity: Greater than...
| Schlagworte: | BRD4, HUNK1, Protein HUNK1, Bromodomain-containing protein 4 |
| Anwendung: | Activity not tested |
| Exprimiert in: | Yeast |
| Ursprungsart: | human |
| MW: | 15.8 kD |
ab 292,00 €
Anti-BRD4 Recombinant Monoclonal
Artikelnummer: A700-005
Protein function: Chromatin reader protein that recognizes and binds acetylated histones and plays a key role in transmission of epigenetic memory across cell divisions and transcription regulation. Remains associated with acetylated chromatin throughout the entire cell cycle and provides epigenetic memory for...
| Schlagworte: | Anti-BRD4, Anti-HUNK1, Anti-Protein HUNK1, Anti-Bromodomain-containing protein 4 |
| Anwendung: | WB, IP, IHC, IHC-IF, ICC-IF, FC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 185,00 €
BRD4 Inhibitor-27
Artikelnummer: TGM-T78555-100mg
Description: BRD4 Inhibitor-27 is a potent BRD4 inhibitor that inhibits BRD4 BD1 and BRD4 BD2 with IC50s of 9.6 and 11.3 µM, respectively.BRD4 Inhibitor-27 has anticancer activity and can be used for breast cancer research. Target: Epigenetic Reader Domain. Smiles: FC(F)(F)C1=NN=C2C=CC(NCCC3=CNC4=C3C=CC=C4)=NN12....
| Anwendung: | BRD4 inhibitor |
| CAS | 930039-92-2 |
| MW: | 346.31 D |
ab 194,00 €
BRD4 Protein, Human, Recombinant (His & Flag)
Artikelnummer: TGM-TMPJ-00694-10ug
Description: Bromodomain-containing protein 4 (BRD4) is a member of the BET class chromatin reader proteins that bind acetylated histones and play a key role in transcriptional regulation and transmission of epigenetic memory. Remains associated with acetylated chromatin throughout the entire cell cycle and provides...
| Schlagworte: | HUNK1, HUNKI, MCAP, bromodomain-containing protein 4 |
| MW: | 60 kD |
ab 75,00 €
Molibresib
Artikelnummer: TGM-T1906-100mg
Description: Molibresib (GSK525762) is an inhibitor of BET proteins (IC50: about 35 nM). Target: Epigenetic Reader Domain. Smiles: CCNC(=O)C[C@@H]1N=C(c2ccc(Cl)cc2)c2cc(OC)ccc2-n2c(C)nnc12. References: Nicodeme E, et al. Nature, 2010, 468(7327), 1119-1123.
| Schlagworte: | GSK 525762A, GSK525762, I-BET 762 |
| Anwendung: | Targets bromodomain-containing protein 4 (BRD4) |
| CAS | 1260907-17-2 |
| MW: | 423.9 D |
ab 37,00 €
MS436
Artikelnummer: TGM-T1854-100mg
Description: MS436 is a selective, small-molecule inhibitor for the BRD4 bromodomains. Target: Epigenetic Reader Domain. Smiles: Cc1cc(\N=N\c2ccc(cc2)S(=O)(=O)Nc2ccccn2)c(N)cc1O. References: Zhang G, et al. J Med Chem. 2013, 56(22), 9251-9264.
| Anwendung: | Bromodomain inhibitor, BRD4 inhibitor |
| CAS | 1395084-25-9 |
| MW: | 383.42 D |
ab 38,00 €
BRD4 Inhibitor-19
Artikelnummer: TGM-T63302-100mg
Description: BRD4 inhibitors -19 are BET inhibitors that act on BRD4-BD1 (IC50: 55 nM) and can be used to study multiple myeloma. Target: Others. Smiles: C(N1C(C=2C(N(C)C1=O)=CC=C(C2)C=3C(C)=NOC3C)C4=CC=CC=C4)C=5OC(=NN5)C6=CC=CC=C6
| Anwendung: | BRD4 inhibitor |
| CAS | 2757865-63-5 |
| MW: | 491.54 D |
ab 1.520,00 €
BRD4 Inhibitor-18
Artikelnummer: TGM-T63352-100mg
Description: BRD4 Inhibitor-18 is a potent BRD4 inhibitor (IC50: 110 nM) with a hydrophobic acetylcyclopentane side chain. BRD4 Inhibitor-18 significantly reduces the proliferation of MV-4-11 cells with high BRD4 levels, inhibits G0/G1 cycle activity, and promotes apoptosis. The inhibition of G0/G1 cycle activity...
| Anwendung: | BRD4 inhibitor |
| CAS | 2451219-73-9 |
| MW: | 496.02 D |
ab 2.142,00 €
PFI-1
Artikelnummer: TGM-T6222-100mg
Description: PFI-1 (PF-6405761), a specific BET (bromodomain-containing protein) inhibitor for BRD4, is with the IC50 of 0.22 µM in a cell-free assay. Target: Autophagy, Apoptosis, Epigenetic Reader Domain. Smiles: COc1ccccc1S(=O)(=O)Nc1ccc2NC(=O)N(C)Cc2c1. References: Fish PV, et al. J Med Chem, 2012, 55(22),...
| Schlagworte: | PFI 1, PFI1, PF-6405761 |
| Anwendung: | Bromodomain inhibitor |
| CAS | 1403764-72-6 |
| MW: | 347.39 D |
ab 43,00 €