Zu "K11722" wurden 115 Artikel gefunden!
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-15 %
Rabattaktion
Anti-BRD4
Artikelnummer: A301-985A100
Protein function: Chromatin reader protein that recognizes and binds acetylated histones and plays a key role in transmission of epigenetic memory across cell divisions and transcription regulation. Remains associated with acetylated chromatin throughout the entire cell cycle and provides epigenetic memory for...
| Schlagworte: | Anti-BRD4, Anti-HUNK1, Anti-Protein HUNK1, Anti-Bromodomain-containing protein 4 |
| Anwendung: | WB, IP, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
1.090,00 €
926,50 €
-15 %
Rabattaktion
Anti-BRD4
Artikelnummer: A301-985A50
Protein function: Chromatin reader protein that recognizes and binds acetylated histones and plays a key role in transmission of epigenetic memory across cell divisions and transcription regulation. Remains associated with acetylated chromatin throughout the entire cell cycle and provides epigenetic memory for...
| Schlagworte: | Anti-BRD4, Anti-HUNK1, Anti-Protein HUNK1, Anti-Bromodomain-containing protein 4 |
| Anwendung: | WB, IP, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
623,00 €
529,55 €
(+)-JQ1
Artikelnummer: Cay11187-5
The bromodomain and extra terminal domain (BET) family of proteins, including BRD2, BRD3, and BRD4, play a key role in many cellular processes, including inflammatory gene expression, mitosis, and viral/host interaction by controlling the assembly of histone acetylation-dependent chromatin complexes. JQ1 displaces...
| Schlagworte: | (6S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetic acid,... |
| Anwendung: | BRD4 inhibitor |
| CAS | 1268524-70-4 |
| MW: | 457 D |
ab 35,00 €
NEU
Bromodomain-containing protein 4 (BRD4), partial, human,...
Artikelnummer: CSB-EP002802HU.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 150-200aa. Protein Length: Partial. Tag Info: N-terminal 6xHis-GST-tagged. Target Protein Sequence: AEALEKLFLQ KINELPTEET EIMIVQAKGR GRGRKETGTA KPGVSTVPNT T. Purity: Greater than 85% as determined by SDS-PAGE. Endotoxin: Not test. Biological...
| Schlagworte: | BRD4, HUNK1, Protein HUNK1, Bromodomain-containing protein 4, Recombinant Human Bromodomain-containing protein 4 (BRD4),... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 5.5 kD |
ab 240,00 €
NEU
AT-1
Artikelnummer: Cay33265-1
AT-1 is a proteolysis-targeting chimera (PROTAC) that contains the bromodomain and extra terminal (BET) domain-containing protein inhibitor (+)-JQ1 (Cay-11187) conjugated to PROTAC building block VH ligand 032 (Cay-39982). It selectively degrades bromodomain-containing protein 4 (BRD4) over BRD3 and BRD2 in HeLa...
| Schlagworte: | (4R)-N-acetyl-3-[[6-[[2-[(6S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl]... |
| Anwendung: | BRD4 degradation driving PROTAC |
| CAS | 2098836-45-2 |
| MW: | 972.7 D |
ab 64,00 €
NEU
Human BRD4 Protein, hFc Tag
Artikelnummer: DIM-PME100915.10
Recombinant human BRD4 protein with C-terminal human Fc tag. BRD4(Met1-Phe1362) hFc(Glu99-Ala330), Protein function: Chromatin reader protein that recognizes and binds acetylated histones and plays a key role in transmission of epigenetic memory across cell divisions and transcription regulation. Remains associated...
| Schlagworte: | CAP, HUNK1, HUNKI, MCAP |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 178.4 kD |
ab 109,00 €
-15 %
Rabattaktion
Anti-BRD4 Recombinant Monoclonal
Artikelnummer: A700-005
Protein function: Chromatin reader protein that recognizes and binds acetylated histones and plays a key role in transmission of epigenetic memory across cell divisions and transcription regulation. Remains associated with acetylated chromatin throughout the entire cell cycle and provides epigenetic memory for...
| Schlagworte: | Anti-BRD4, Anti-HUNK1, Anti-Protein HUNK1, Anti-Bromodomain-containing protein 4 |
| Anwendung: | WB, IP, IHC, IHC-IF, ICC-IF, FC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
172,00 €
ab 146,20 €
Human BRD4 (Bromodomain Containing Protein 4) ELISA Kit
Artikelnummer: ELK-ELK5398.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human BRD4. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human BRD4. Next,...
| Schlagworte: | BRD4, HUNK1, Protein HUNK1, Bromodomain-containing protein 4 |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
ab 365,00 €
RVX-297
Artikelnummer: Cay38777-10
RVX-297 is an inhibitor of the bromodomain and extra-terminal domain (BET) family protein bromodomain 2 (BD2). It inhibits BD2 in bromodomain-containing protein 2 (BRD2), BRD3, and BRD4, (IC50s = 0.08, 0.05, and 0.02 µM, respectively) and is selective for BD2 over BD1 (IC50s = 3.76, 2.34, and 1.16 µM for BRD2, BRD3,...
| Schlagworte: | 2-[3,5-dimethyl-4-[2-(1-pyrrolidinyl)ethoxy]phenyl]-5,7-dimethoxy-4(3H)-quinazolinone |
| Anwendung: | BD2 bromodomain inhibitor |
| CAS | 1044871-04-6 |
| MW: | 423.5 D |
ab 101,00 €
-15 %
Rabattaktion
Anti-BRD4 Recombinant Monoclonal
Artikelnummer: A700-004
Protein function: Chromatin reader protein that recognizes and binds acetylated histones and plays a key role in transmission of epigenetic memory across cell divisions and transcription regulation. Remains associated with acetylated chromatin throughout the entire cell cycle and provides epigenetic memory for...
| Schlagworte: | Anti-BRD4, Anti-HUNK1, Anti-Protein HUNK1, Anti-Bromodomain-containing protein 4 |
| Anwendung: | WB, IP, IHC, ICC, ICC-IF, ChIP-Seq, FC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
172,00 €
ab 146,20 €
(+)-JQ1 Bromodomain Inhibitor
Artikelnummer: BPS-27400
(+)-JQ1 is a specific inhibitor of the BET family of acetyl-lysine recognition motifs, including the BRD2, BRD3, BRD4 and BRDT bromodomains. (+)-JQ1 has been shown to inhibit BRD4 (BD1) with a Kd of 50 nM, and BRD4 (BD2) with a Kd of 90 nM.
| Schlagworte: | BET inhibitor, Bromodomain inhibitor, |
| Anwendung: | BRD inhibitor |
| MW: | 456.99 D |
360,00 €
BRD4 (49-170), His-tag, human recombinant protein
Artikelnummer: BPS-31042
Human Bromodomain containing 4, also known as BRD4, HUNK1, or MCAP, amino-acids 49-170 (GenBank Accession No. NM_058243) with N-terminal His tag, MW = 15.5 kDa, expressed in an E. coli expression system.
| Schlagworte: | BRD4, HUNK1, Protein HUNK1, Bromodomain-containing protein 4, |
| Anwendung: | Binding assays, inhibitor screening, selectivity profiling |
| MW: | 15.5 kD |
452,00 €