Zu "K11481" wurden 133 Artikel gefunden!
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Anti-AURKA
Artikelnummer: ABS-KC-2294.100
Protein function: Mitotic serine/threonine kinase that contributes to the regulation of cell cycle progression (PubMed:26246606). Associates with the centrosome and the spindle microtubules during mitosis and plays a critical role in various mitotic events including the establishment of mitotic spindle, centrosome...
| Schlagworte: | Anti-Aurora kinase A, Anti-Aurora 2, Anti-Aurora/IPL1-related kinase 1, Anti-ARK-1, Anti-Aurora-related kinase 1,... |
| Anwendung: | IHC |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
ab 206,00 €
Anti-AURKA
Artikelnummer: ABS-KC-2618.100
Protein function: Mitotic serine/threonine kinase that contributes to the regulation of cell cycle progression (PubMed:26246606). Associates with the centrosome and the spindle microtubules during mitosis and plays a critical role in various mitotic events including the establishment of mitotic spindle, centrosome...
| Schlagworte: | Anti-Aurora kinase A, Anti-Aurora 2, Anti-Aurora/IPL1-related kinase 1, Anti-ARK-1, Anti-Aurora-related kinase 1,... |
| Anwendung: | IP |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
ab 206,00 €
Anti-AURKA
Artikelnummer: ABS-KC-6096.100
Protein function: Mitotic serine/threonine kinase that contributes to the regulation of cell cycle progression (PubMed:26246606). Associates with the centrosome and the spindle microtubules during mitosis and plays a critical role in various mitotic events including the establishment of mitotic spindle, centrosome...
| Schlagworte: | Anti-Aurora kinase A, Anti-Aurora 2, Anti-Aurora/IPL1-related kinase 1, Anti-ARK-1, Anti-Aurora-related kinase 1,... |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human, monkey |
ab 232,00 €
LY3295668
Artikelnummer: Cay27914-1
LY3295668 is an inhibitor of Aurora A kinase (IC50 = 2 phase in HeLa cells (IC50 = 108 nM). In vivo, LY3295668 (40 mg/kg per day) decreases tumor volume in a patient-derived xenograft (PDX) mouse model of small cell lung cancer.Formal Name:...
| Schlagworte: | AK-01,... |
| Anwendung: | Aurora A kinase inhibitor |
| CAS | 1919888-06-4 |
| MW: | 490 D |
ab 103,00 €
CD532
Artikelnummer: TGM-T50110-10mg
Description: CD532 is A highly potent Aurora A kinase inhibitor with an IC50 value of 45 nM. CD532 can block Aurora A kinase activity, drive MYCN degradation, and can directly interact with AURKA and induce global conformational transformation. CD532 can be used to study cancer. Target: Aurora Kinase. Smiles:...
| Anwendung: | Aurora A kinase activity inhibitor, Aurora A-N-Myc protein-protein interaction inhibitor |
| CAS | 1639009-81-6 |
| MW: | 522.52 D |
ab 34,00 €
MLN8054
Artikelnummer: TGM-T6315-100mg
Description: MLN8054 is a potent and selective Aurora A kinase inhibitor with an IC50 of 4 nM. Target: PKA, Aurora Kinase, Casein Kinase, Src. Smiles: OC(=O)c1ccc(Nc2ncc3CN=C(c4cc(Cl)ccc4-c3n2)c2c(F)cccc2F)cc1. References: Manfredi MG, et al. Proc Natl Acad Sci U S A, 2007, 104(10), 4106-4111.
| Anwendung: | Aurora A kinase ATP-competitive inhibitor |
| CAS | 869363-13-3 |
| MW: | 476.86 D |
ab 48,00 €
Aurora kinase inhibitor-3
Artikelnummer: TGM-T5524-100mg
Description: Aurora kinase inhibitor-3 (Aurora Kinase Inhibitor III) is a potent inhibitor of Aurora A kinase (IC50 = 42 nM).1 It is selective for Aurora A over BMX, BTK, IGF-1R, c-Src, TRKB, SYK, and EGFR. Target: Aurora Kinase. Smiles: FC(F)(F)c1cccc(Nc2ccnc(Nc3cccc(NC(=O)C4CC4)c3)n2)c1. References: Zhang Q , Liu...
| Schlagworte: | Aurora Kinase Inhibitor III |
| Anwendung: | Aurora kinase inhibitor |
| CAS | 879127-16-9 |
| MW: | 413.4 D |
ab 71,00 €
Aurora A inhibitor 2
Artikelnummer: TGM-T62647-100mg
Description: Aurora A inhibitor 2 (Compound 16h) is a potent Aurora A kinase inhibitor with an IC50 of 21.94 nM. Target: Others. Smiles: N(C(CC)=O)C=1NC=2C(N1)=CC=C(C2)C=3C=C4C(=CC3)N=CN(CCN5CCOCC5)C4=O
| Anwendung: | Aurora A inhibitor |
| CAS | 2412144-74-0 |
| MW: | 446.5 D |
ab 1.520,00 €
Aurora kinase inhibitor-9
Artikelnummer: TGM-T62789-50mg
Description: Aurora kinase inhibitor-9 (compound 9d) is a potent AURKA/B bipolar kinase inhibitor with an IC50 of 0.093 µM for Aurora A and 0.09 µM for Aurora B, demonstrating broad-spectrum anti-proliferative activity. Target: Others. Smiles: N(C=1C2=C(N=CC1C(OCC)=O)C=C(Cl)C=C2Cl)C3=CC(S(NC)(=O)=O)=CC=C3
| Anwendung: | Aurora kinase inhibitor |
| CAS | 2419107-09-6 |
| MW: | 454.33 D |
ab 1.520,00 €
Alisertib sodium hydrate
Artikelnummer: TGM-T71232-100mg
Description: Alisertib sodium hydrate is a salt of Alisertib --- an inhibitor of Aurora A kinase with potential antineoplastic activity. Alisertib binds to and inhibits Aurora A kinase, which may result in disruption of the assembly of the mitotic spindle apparatus, disruption of chromosome segregation, and...
| Anwendung: | Targets aurora kinase A [EC:2.7.11.1] (AURKA) |
| CAS | 1208255-63-3 |
| MW: | 558.93 D |
ab 1.671,00 €
Tripolin A
Artikelnummer: TGM-T8537-25mg
Description: Tripolin A is a specific non-ATP competitive inhibitor of Aurora A kinase(Aurora A and Aurora B with IC50 values of 1.5 µM and 7 µM, respectively). Target: Aurora Kinase. Smiles: C(=C/1\C=2C(NC1=O)=CC=CC2)\C3=C(O)C=CC(O)=C3. References: Iliana A Kesisova, et al. Tripolin A, a Novel Small-Molecule...
| Anwendung: | Aurora A kinase inhibitor |
| CAS | 1148118-92-6 |
| MW: | 253.25 D |
817,00 €
Aurora kinase inhibitor-2
Artikelnummer: TGM-T9040-100mg
Description: Aurora kinase inhibitor-2 (IUN-70219) is a cell-permeable anilinoquinazoline that inhibit the activity of Aurora A (IC50 = 0.39 M). Target: Aurora Kinase. Smiles: COc1cc2ncnc(Nc3ccc(NC(=O)c4ccccc4)cc3)c2cc1OC. References: Heron N M , Anderson M , Blowers D P , et al. SAR and inhibitor complex structure...
| Schlagworte: | Aurora Kinase Inhibitor II, IUN-70219 |
| Anwendung: | Aurora kinase inhibitor |
| CAS | 331770-21-9 |
| MW: | 400.43 D |
ab 60,00 €