Zu "K11481" wurden 125 Artikel gefunden!
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Aurora kinase A (AURKA), human, recombinant
Artikelnummer: CSB-EP002454HU.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 1-403aa. Protein Length: Full Length. Tag Info: N-terminal 6xHis-tagged. Target Protein Sequence: MDRSKENCIS GPVKATAPVG GPKRVLVTQQ FPCQNPLPVN SGQAQRVLCP SNSSQRIPLQ AQKLVSSHKP VQNQKQKQLQ ATSVPHPVSR PLNNTQKSKQ PLPSAPENNP EEELASKQKN EESKKRQWAL...
| Schlagworte: | AIK, AURKA, hARK1, ARK-1, Aurora 2, Aurora kinase A, Aurora-related kinase 1, Aurora/IPL1-related kinase 1, Breast... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 51.8 kD |
ab 283,00 €
Anti-AURKA
Artikelnummer: CSB-PA000924.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-AIK, Anti-AURKA, Anti-hARK1, Anti-ARK-1, Anti-Aurora 2, Anti-Aurora kinase A, Anti-Aurora-related kinase 1,... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 106,00 €
Anti-AURKA
Artikelnummer: CSB-PA000925.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-AIK, Anti-AURKA, Anti-hARK1, Anti-ARK-1, Anti-Aurora 2, Anti-Aurora kinase A, Anti-Aurora-related kinase 1,... |
| Anwendung: | ELISA, WB, IHC, IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat, monkey |
ab 106,00 €
Anti-Phospho-AURKA (T288)
Artikelnummer: CSB-PA050175.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-phospho-AIK, Anti-phospho-AURKA, Anti-phospho-hARK1, Anti-phospho-ARK-1, Anti-phospho-Aurora 2, Anti-phospho-Aurora... |
| Anwendung: | ELISA, WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 106,00 €
Anti-AURKA Recombinant Monoclonal, clone 1H8
Artikelnummer: CSB-RA223479A0HU.100
Isotype: Rabbit IgG. Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Affinity-chromatography. Target Name: AURKA. Antigen Species: Human
| Schlagworte: | Anti-AIK, Anti-AURKA, Anti-hARK1, Anti-ARK-1, Anti-Aurora 2, Anti-Aurora kinase A, Anti-Aurora-related kinase 1,... |
| Anwendung: | ELISA, IF, Recommended dilution: IF:1:20-1:200 |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 201,00 €
Anti-Phospho-AURKA (Thr288)
Artikelnummer: CSB-PA959104.100
Host Species: Rabbit. Isotype: IgG. Buffer: Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antibodies were produced by immunizing rabbits...
| Schlagworte: | Anti-phospho-AIK, Anti-phospho-AURKA, Anti-phospho-hARK1, Anti-phospho-ARK-1, Anti-phospho-Aurora 2, Anti-phospho-Aurora... |
| Anwendung: | ELISA, WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
330,00 €
AKI-603
Artikelnummer: Cay40840-1
AKI-603 is an inhibitor of Aurora A kinase (IC50 = 12 nM). It reduces the proliferation of HL-60 promyeoloblast leukemia cells, K562 chronic myeloid leukemia (CML) cells, U937 lymphoma monocytes, MOLT-4 T cell lymphoblasts, and MCF-7 and MDA-MD-231 breast cancer cells (IC50s = 69, 137, 43, 18, 424, and 84 nM,...
| Schlagworte: | 6-(4-methyl-1-piperazinyl)-N4-(5-methyl-1H-pyrazol-3-yl)-N2-(4-nitrophenyl)-2,4-pyrimidinediamine |
| Anwendung: | Aurora A kinase inhibitor |
| CAS | 1432515-73-5 |
| MW: | 409.5 D |
ab 141,00 €
Phthalazinone pyrazole
Artikelnummer: Cay10735-1
Three Aurora kinases, A-C, are involved in phosphorylation events that are critical for the completion of mitosis. Aurora A, involved in centrosomal assembly and acentrosomal spindle assembly, is overexpressed in many tumors. Phthalazinone pyrazole is a potent inhibitor of Aurora A kinase (IC50 = 31 nM). It does not...
| Schlagworte: | 4-[(5-methyl-1H-pyrazol-3-yl)amino]-2H-phenyl-1-phthalazinone |
| CAS | 880487-62-7 |
| MW: | 317.4 D |
ab 92,00 €
MLN8237
Artikelnummer: Cay13602-1
MLN8237 is an inhibitor of Aurora A kinase (IC50 = 1 nM). It is selective for Aurora A over Aurora B kinase (IC50 = 396.5 nM). MLN8237 (50 nM) induces cell cycle arrest at the G2/M phase and chromosomal misalignment in HCT116 colon cancer cells. It inhibits tumor growth in a Calu-6 non-small cell lung cancer (NSCLC)...
| Schlagworte: | Alisertib, 4-[[9-chloro-7-(2-fluoro-6-methoxyphenyl)-5H-pyrimido[5,4-d][2]benzazepin-2-yl]amino]-2-methoxy benzoic acid |
| Anwendung: | Aurora A kinase inhibitor |
| CAS | 1028486-01-2 |
| MW: | 518.9 D |
ab 43,00 €
MLN8237
Artikelnummer: LKT-M4652.10
MLN8237 inhibits aurora kinase A (AurA) preventing mitotic spindle formation and proper completion of mitosis. MLN8237 exhibits anticancer chemotherapeutic activity and is currently in clinical trials as a potential treatment for multiple myeloma, non-Hodgkin's lymphoma, and chronic lymphocytic leukemia (CLL). In...
| Schlagworte: | Alisertib |
| Anwendung: | Aurora A kinase inhibitor |
| CAS | 1028486-01-2 |
| MW: | 518.92 D |
ab 156,00 €
Anti-Aurora A
Artikelnummer: A300-071A
Protein function: Mitotic serine/threonine kinase that contributes to the regulation of cell cycle progression. Associates with the centrosome and the spindle microtubules during mitosis and plays a critical role in various mitotic events including the establishment of mitotic spindle, centrosome duplication,...
| Schlagworte: | Anti-AIK, Anti-AURKA, Anti-ARK-1, Anti-hARK1, Anti-Aurora 2, EC=2.7.11.1, Anti-Aurora kinase A, Anti-Aurora-related kinase... |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 164,00 €
Aurora Kinase A, active human recombinant protein
Artikelnummer: BPS-40004
Active human Aurora kinase A (GenBank Accession No. NM_003600), (a.a. 2- 403) with N-terminal HIS6 tag, MW=50 kDa, expressed in a Baculovirus infected Sf9 cell expression system.
| Schlagworte: | ARK-1, Aurora 2, Aurora kinase A, Aurora-related kinase 1, Aurora/IPL1-related kinase 1, Breast tumor-amplified kinase,... |
| Anwendung: | Enzyme kinetics, inhibitor screening |
| MW: | 50 kD |
525,00 €