Zu "K11459" wurden 76 Artikel gefunden!
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BMI-1 Protein, Human, Recombinant (GST)
Artikelnummer: TGM-TMPH-01886-100ug
Description: BMI-1 Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 56.4 kDa and the accession number is P35226.
| Schlagworte: | RING finger protein 51, Polycomb group RING finger protein 4, RNF51, Polycomb complex protein BMI-1, BMI1, PCGF4 |
| MW: | 56.4 kD |
ab 198,00 €
Unesbulin
Artikelnummer: TGM-T12575-100mg
Description: Unesbulin (PTC596) is an orally active, selective inhibitor of B-cell-specific Moloney murine leukemia virus integration site 1 (BMI-1). Target: Apoptosis, BMI-1. Smiles: Cc1nc2ccc(F)cc2n1-c1nc(N)c(F)c(Nc2ccc(cc2)C(F)(F)F)n1. References: Nishida Y, et al. The novel BMI-1 inhibitor PTC596 downregulates...
| Schlagworte: | PTC596 |
| Anwendung: | Targets polycomb group RING finger protein 4 (PCGF4, BMI1) |
| CAS | 1610964-64-1 |
| MW: | 420.34 D |
ab 88,00 €
PTC-028
Artikelnummer: TGM-T16680-100mg
Description: PTC-028 selectively suppresses cancer cells whereas normal cells remain unaffected. PTC-028 is an orally bioavailable inhibitor of stem cell factor BMI-1 in ovarian cancer. The depletion of BMI-1 by PTC-028 causes caspase-mediated apoptosis. Target: Apoptosis, BMI-1. Smiles:...
| Anwendung: | BMI1 inhibitor |
| CAS | 1782970-28-8 |
| MW: | 405.32 D |
ab 40,00 €
Polycomb complex protein BMI-1 (BMI1), partial, human,...
Artikelnummer: CSB-EP002726HU1.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 1-250aa. Protein Length: Partial. Tag Info: N-terminal GST-tagged. Target Protein Sequence: MHRTTRIKIT ELNPHLMCVL CGGYFIDATT IIECLHSFCK TCIVRYLETS KYCPICDVQV HKTRPLLNIR SDKTLQDIVY KLVPGLFKNE MKRRRDFYAA HPSADAANGS NEDRGEVADE DKRIITDDEI ISLSIEFFDQ...
| Schlagworte: | BMI1, PCGF4, RING finger protein 51, Polycomb complex protein BMI-1, Polycomb group RING finger protein 4, Recombinant... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 56.4 kD |
ab 219,00 €
Anti-BMI1
Artikelnummer: CSB-PA03345A0Rb.100
Host Species: Rabbit. Isotype: IgG. Buffer: Preservative: 0.03% Proclin 300Constituents: 50% Glycerol, 0.01M PBS, PH 7.4. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: >95%, Protein G purified. Target Name: BMI1. Antigen Species: Human
| Schlagworte: | Anti-BMI1, Anti-PCGF4, Anti-RING finger protein 51, Anti-Polycomb complex protein BMI-1, Anti-Polycomb group RING finger... |
| Anwendung: | ELISA, WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 167,00 €
Anti-BMI1
Artikelnummer: CSB-PA288653.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: BMI1. Antigen Species: Human
| Schlagworte: | Anti-BMI1, Anti-PCGF4, Anti-RING finger protein 51, Anti-Polycomb complex protein BMI-1, Anti-Polycomb group RING finger... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 167,00 €
Anti-BMI1
Artikelnummer: A301-694A
Protein function: Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates...
| Schlagworte: | Anti-BMI1, Anti-PCGF4, Anti-RING finger protein 51, Anti-Polycomb complex protein BMI-1, Anti-Polycomb group RING finger... |
| Anwendung: | WB, IP, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 178,00 €
PTC-209
Artikelnummer: Cay16277-1
Polycomb complex protein BMI-1 is a polycomb ring finger oncogene that regulates the p16 and p19 cell cycle inhibitor genes. It is necessary for efficient self-renewing cell divisions of stem cells in several tissues and can be over-expressed in tumors. PTC-209 is a BMI-1 inhibitor (IC50 = ~ 0.5 µM) that...
| Schlagworte: | N-(2,6-dibromo-4-methoxyphenyl)-4-(2-methylimidazo[1,2-a]pyrimidin-3-yl)-2-thiazolamine |
| Anwendung: | BMI-1 inhibitor |
| CAS | 315704-66-6 |
| MW: | 495.2 D |
ab 40,00 €
Anti-BMI1 (IHC)
Artikelnummer: IHC-00606
Protein function: Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates...
| Schlagworte: | Anti-BMI1, Anti-PCGF4, Anti-RING finger protein 51, Anti-Polycomb complex protein BMI-1, Anti-Polycomb group RING finger... |
| Anwendung: | IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 178,00 €
PTC-596
Artikelnummer: Cay33529-1
PTC-596 is an inhibitor of B cell-specific Moloney murine leukemia virus integration site 1 (BMI1), which is a member of the polycomb repressive complex 1 (PRC1) that has a role in gene silencing. It inhibits proliferation of MOLM-13 acute myeloid leukemia (AML) and Rec-1 mantle cell lymphoma (MCL) cancer cells...
| Schlagworte: | Unesbulin, 5-fluoro-2-(6-fluoro-2-methyl-1H-benzimidazol-1-yl)-N4-[4-(trifluoromethyl)phenyl]-4,6-pyrimidinediamine |
| Anwendung: | BMI1 inhibitor |
| CAS | 1610964-64-1 |
| MW: | 420.3 D |
ab 108,00 €
Anti-BMI1
Artikelnummer: BPS-25210
BMI1 (UniProtKB/Swiss Prot entry P35226) is a component of a Polycomb group (PcG) multiprotein PRC1 like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. The PcG PRC1 complex acts via chromatin remodeling and modification...
| Schlagworte: | Anti-BMI1, Anti-PCGF4, Anti-RING finger protein 51, Anti-Polycomb complex protein BMI-1, Anti-Polycomb group RING finger... |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
742,00 €
Anti-Bmi-1 (BMI1, RNF51, MGC12685, BUP, C10orf8, PCGF4,...
Artikelnummer: 600-101-392
Protein function: Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates...
| Schlagworte: | Anti-BMI1, Anti-PCGF4, Anti-RING finger protein 51, Anti-Polycomb complex protein BMI-1, Anti-Polycomb group RING finger... |
| Anwendung: | ELISA, IFM, WB |
| Wirt: | Goat |
| Spezies-Reaktivität: | human |
719,00 €