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Zu "K11448" wurden 29 Artikel gefunden!
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Artikelnummer: CSB-PA174245.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: KDM6B. Antigen Species: Human
Schlagworte: | Anti-JMJD3, Anti-KDM6B, Anti-Lysine demethylase 6B, Anti-Lysine-specific demethylase 6B, Anti-JmjC domain-containing... |
Anwendung: | ELISA, WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse |
ab 163,00 €
Artikelnummer: CSB-EP517674HU.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 1530-1682aa. Protein Length: Partial of Isoform 1. Tag Info: C-terminal 6xHis-tagged. Target Protein Sequence: PDLFKMIKFC LLQSMKHCQV QRESLVRAGK KIAYQGRVKD EPAYYCNECD VEVFNILFVT SENGSRNTYL VHCEGCARRR SAGLQGVVVL EQYRTEELAQ AYDAFTLVRA RRARGQRRRA...
Schlagworte: | JMJD3, KDM6B, Lysine demethylase 6B, Lysine-specific demethylase 6B, JmjC domain-containing protein 3, Jumonji... |
Anwendung: | Activity not tested |
Exprimiert in: | E.coli |
Ursprungsart: | human |
MW: | 23.9 kD |
ab 283,00 €
Artikelnummer: CSB-EP517674HU1.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 1176-1505aa. Protein Length: Partial. Tag Info: N-terminal 6xHis-tagged. Target Protein Sequence: LPREKLNPPT PSIYLESKRD AFSPVLLQFC TDPRNPITVI RGLAGSLRLN LGLFSTKTLV EASGEHTVEV RTQVQQPSDE NWDLTGTRQI WPCESSRSHT TIAKYAQYQA SSFQESLQEE KESEDEESEE...
Schlagworte: | JMJD3, KDM6B, Lysine demethylase 6B, Lysine-specific demethylase 6B, JmjC domain-containing protein 3, Jumonji... |
Anwendung: | Activity not tested |
Exprimiert in: | E.coli |
Ursprungsart: | human |
MW: | 41.5 kD |
ab 283,00 €
Artikelnummer: Cay12073-5
The histone H3 lysine 27 (H3K27) demethylase JMJD3 plays important roles in the transcriptional regulation of cell differentiation, development, the inflammatory response, and cancer. GSK-J4 (hydrochloride) is an ethyl ester derivative of the JMJD3 selective histone demethylase inhibitor GSK-J1 (Cay-12054) with an...
Schlagworte: | N-[2-(2-pyridinyl)-6-(1,2,4,5-tetrahydro-3H-3-benzazepin-3-yl)-4-pyrimidinyl]-beta-alanine, ethyl ester, monohydrochloride |
Anwendung: | Histone demethylase inhibitor |
CAS | 1797983-09-5 |
MW: | 454 D |
ab 77,00 €
Artikelnummer: Cay15338-5
JIB-04 is a pyridine hydrazone that broadly inhibits Jumonji histone demethylases (IC50s values = 230, 340, 435, 445, 855 and 1,100 nM for JARID1A, JMJD2E, JMJD2B, JMJD2A, JMJD3, and JMJD2C, respectively). It does not inhibit histone deacetylases and has minimal effect on the iron-containing enzymes methylcytosine...
Schlagworte: | JHDM Inhibitor VII, NSC 693627, phenyl-2-pyridinyl-methanone, (E,E)-2-(5-chloro-2-pyridinyl)hydrazone |
Anwendung: | Jumonji histone demethylase inhibitor |
CAS | 199596-05-9 |
MW: | 308.8 D |
ab 109,00 €
Artikelnummer: BPS-50115
Human JMJD3/KDM6B histone demethylase (a.a. 1000-end) expressed in Sf9 cells. Methylation of Lys27 of histone H3 (H3K27) is a silencing mark associated with imprinting and X chromosome activation. JMJD3 is a histone demethylase that demethylates di- and trimethyl-lysine 27 on histone H3, JMJD3 also plays important...
Schlagworte: | KDM6B, JMJD3, Lysine demethylase 6B, Lysine-specific demethylase 6B, JmjC domain-containing protein 3, Jumonji... |
Anwendung: | Enzyme kinetics, inhibitor screening, HTS |
MW: | 71 kD |
701,00 €
Artikelnummer: Cay12054-5
The histone H3 lysine 27 (H3K27) demethylase JMJD3 plays important roles in the transcriptional regulation of cell differentiation, development, the inflammatory response, and cancer. GSK-J1 is a potent inhibitor of the H3K27 histone demethylases JMJD3 and UTX (IC50s = 18 and 56 µM, respectively as measured by mass...
Schlagworte: | N-[2-(2-pyridinyl)-6-(1,2,4,5-tetrahydro-3H-3-benzazepin-3-yl)-4-pyrimidinyl]-beta-alanine, monosodium salt |
Anwendung: | JMJD3 inhibitor |
CAS | 1797832-71-3 |
MW: | 411.4 D |
ab 43,00 €
Artikelnummer: NSJ-F52856-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. Histone demethylase that specifically demethylates 'Lys- 27' of histone H3, thereby playing a central role in histone code. Demethylates trimethylated and dimethylated H3 'Lys-27'. Plays a central role in regulation of posterior development, by regulating HOX gene...
Schlagworte: | Anti-Jmjd3, Anti-Kdm6b, EC=1.14.11.-, Anti-Lysine-specific demethylase 6B, Anti-JmjC domain-containing protein 3,... |
Anwendung: | WB, ELISA |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse |
ab 326,00 €
Artikelnummer: BPS-50406
The JMJD3 Chemiluminescent Assay Kit is designed to measure JMJD3 activity for screening and profiling applications. JMJD3 is a JmjC-domain protein that exhibits demethylation activity toward di- and trimethyl-lysine 27 (H3K27me2/3) on histone H3. The JMJD3 Assay Kit comes in a convenient format, with 8-well strips...
Schlagworte: | JMJD3, KDM6B, |
Anwendung: | Enzyme kinetics, HTS |
1.065,00 €
Artikelnummer: BPS-50416-1
The JMJD3 Homogeneous Assay Kit is designed to measure activity of the JMJD3 for screening and profiling applications. JMJD3 is a JmjC-domain protein that exhibits demethylation activity toward di- and trimethyl-lysine 27 (H3K27me2/3) on histone H3. The JMJD3 Homogeneous Assay Kit comes in a convenient AlphaLISA®...
Schlagworte: | KDM6B, JMJD3, Lysine demethylase 6B, Lysine-specific demethylase 6B, JmjC domain-containing protein 3, Jumonji... |
Anwendung: | Enzyme kinetics, HTS |
ab 1.021,00 €
Artikelnummer: NSJ-F40552-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. Covalent modification of histones plays critical role in regulating chromatin structure and transcription. While most covalent histone modifications are reversible, only recently has it been established that methyl groups are subject to enzymatic removal from histones. A...
Schlagworte: | Anti-Jmjd3, Anti-Kdm6b, EC=1.14.11.-, Anti-Lysine-specific demethylase 6B, Anti-JmjC domain-containing protein 3,... |
Anwendung: | WB, ELISA |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse |
ab 326,00 €
Artikelnummer: NSJ-F53139-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. Histone demethylase that specifically demethylates 'Lys- 27' of histone H3, thereby playing a central role in histone code. Demethylates trimethylated and dimethylated H3 'Lys-27'. Plays a central role in regulation of posterior development, by regulating HOX gene...
Schlagworte: | Anti-JMJD3, Anti-KDM6B, EC=1.14.11.-, Anti-Lysine demethylase 6B, Anti-Lysine-specific demethylase 6B, Anti-JmjC... |
Anwendung: | WB, ELISA |
Wirt: | Rabbit |
Spezies-Reaktivität: | mouse |
ab 326,00 €