Zu "K11430" wurden 130 Artikel gefunden!
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Histone-lysine N-methyltransferase EZH2 (EZH2), human,...
Artikelnummer: CSB-YP613606HU.1
Organism: Homo sapiens (Human). Source: Yeast. Expression Region: 1-746aa. Protein Length: Full Length. Tag Info: C-terminal 6xHis-tagged. Target Protein Sequence: MGQTGKKSEK GPVCWRKRVK SEYMRLRQLK RFRRADEVKS MFSSNRQKIL ERTEILNQEW KQRRIQPVHI LTSVSSLRGT RECSVTSDLD FPTQVIPLKT LNAVASVPIM YSWSPLQQNF MVEDETVLHN IPYMGDEVLD...
| Schlagworte: | KMT6, ENX-1, Enhancer of zeste homolog 2, Lysine N-methyltransferase 6, Histone-lysine N-methyltransferase EZH2,... |
| Anwendung: | Activity not tested |
| Exprimiert in: | Yeast |
| Ursprungsart: | human |
| MW: | 86.8 kD |
ab 336,00 €
Anti-EZH2 Recombinant Monoclonal, clone 10H8
Artikelnummer: CSB-RA218051A0HU.100
Isotype: Rabbit IgG. Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Affinity-chromatography. Target Name: EZH2. Antigen Species: Human
| Schlagworte: | Anti-KMT6, Anti-ENX-1, Anti-Enhancer of zeste homolog 2, Anti-Lysine N-methyltransferase 6, Anti-Histone-lysine... |
| Anwendung: | ELISA, IHC, Recommended dilution: IHC:1:50-1:200 |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 201,00 €
Anti-EZH2 Recombinant Monoclonal, clone 2C7
Artikelnummer: CSB-RA942183A0HU.100
Isotype: Rabbit IgG. Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Affinity-chromatography. Target Name: EZH2. Antigen Species: Human
| Schlagworte: | Anti-KMT6, Anti-ENX-1, Anti-Enhancer of zeste homolog 2, Anti-Lysine N-methyltransferase 6, Anti-Histone-lysine... |
| Anwendung: | ELISA, IHC, Recommended dilution: IHC:1:50-1:200 |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 201,00 €
Anti-EZH2
Artikelnummer: CSB-PA761728.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: EZH2. Antigen Species: Human
| Schlagworte: | Anti-KMT6, Anti-ENX-1, Anti-Enhancer of zeste homolog 2, Anti-Lysine N-methyltransferase 6, Anti-Histone-lysine... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 163,00 €
NEU
Anti-EZH2
Artikelnummer: CSB-PA934125.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: EZH2. Antigen Species: Human
| Schlagworte: | Anti-KMT6, Anti-ENX-1, Anti-Enhancer of zeste homolog 2, Anti-Lysine N-methyltransferase 6, Anti-Histone-lysine... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 163,00 €
EPZ6438
Artikelnummer: Cay16174-1
EPZ6438 is an orally bioavailable, selective inhibitor of the lysine methyltranferase EZH2 (Ki = 2.5 nM), the enzymatic subunit of polycomb repressive complex 2. It displays a 35-fold selectivity versus EZH1 and >4,500-fold selectivity relative to 14 other histone methyltransferases. EPZ6438 blocks histone H3 lysine...
| Schlagworte: | Tazemetostat,... |
| Anwendung: | EZH2 inhibitor |
| CAS | 1403254-99-8 |
| MW: | 572.7 D |
ab 60,00 €
GSK126
Artikelnummer: Cay15415-1
The histone H3 lysine 27 (H3K27) methyltransferase EZH2 plays an important role in regulating gene expression, and its aberrant activity is linked to the onset and progression of cancer. GSK126 is a selective, S-adenosyl-methionine-competitive small molecule inhibitor of EZH2 methyltransferase activity (Ki = 0.57...
| Schlagworte: | N-[(1,2-dihydro-4,6-dimethyl-2-oxo-3-pyridinyl)methyl]-3-methyl-1-[(1S)-1-methylpropyl]-6-[6-(1-piperazinyl)-3-pyridinyl]-... |
| Anwendung: | Selective EZH2 methyltransferase inhibitor |
| CAS | 1346574-57-9 |
| MW: | 526.7 D |
ab 84,00 €
Human EZH2 (Enhancer Of Zeste Homolog 2) ELISA Kit
Artikelnummer: ELK-ELK3528.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human EZH2. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human EZH2. Next,...
| Schlagworte: | KMT6, ENX-1, Enhancer of zeste homolog 2, Lysine N-methyltransferase 6, Histone-lysine N-methyltransferase EZH2 |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
ab 365,00 €
UNC1999
Artikelnummer: Cay14621-1
The histone H3 lysine 27 (H3K27) methyltransferase EZH2 plays an important role in regulating gene expression, and its aberrant activity is linked to the onset and progression of cancer. UNC1999 is a cell-permeable EZH2 inhibitor (IC50 = 2 nM) that is 22-fold selective over EZH1 and >1,000-fold selective over other...
| Schlagworte: | N-[(1,2-dihydro-6-methyl-2-oxo-4-propyl-3-pyridinyl)methyl]-1-(1-methylethyl)-6-[6-[4-(1-methylethyl)-1-piperazinyl]-3-1H-... |
| Anwendung: | Cell-permeable EZH2 inhibitor |
| CAS | 1431612-23-5 |
| MW: | 569.8 D |
ab 43,00 €
3-Deazaneplanocin A (hydrochloride)
Artikelnummer: Cay11102-500
The lysine methyltransferase EZH2 (KMT6), part of the polycomb repressive complex 2, catalyzes trimethylation of lysine 27 on histone H3 and is involved in proliferation and aggressive cell growth associated with neoplastic cells. 3-Deazaneplanocin A is a cyclopentenyl analog of 3-deazaadenosine, originally...
| Schlagworte: | 2,3-DMMC, 5R-(4-amino-1H-imidazo[4,5-c]pyridin-1-yl)-3-(hydroxymethyl)-3-cyclopentene-1S,2R-diol, monohydrochloride |
| CAS | 120964-45-6 |
| MW: | 298.7 D |
ab 123,00 €
GSK343
Artikelnummer: Cay14094-1
The histone H3 lysine 27 (H3K27) methyltransferase EZH2 plays an important role in regulating gene expression, and its aberrant activity is linked to the onset and progression of cancer. GSK343 is a cell-permeable EZH2 inhibitor (IC50 = 4 nM) that is 60-fold selective over EZH1 and >1,000-fold selective over other...
| Schlagworte: | N-[(1,2-dihydro-6-methyl-2-oxo-4-propyl-3-pyridinyl)methyl]-1-(1-methylethyl)-6-[2-(4-methyl-1-piperazinyl)-4-pyridinyl]-1... |
| Anwendung: | Cell-permeable EZH2 inhibitor |
| CAS | 1346704-33-3 |
| MW: | 541.7 D |
ab 50,00 €
EZH2 chemiluminescent assay kit
Artikelnummer: BPS-52009L
The EZH2/EED/SUZ12/RbAp48/AEBP2 Direct Activity Assay kit is designed to measure EZH2/EED/SUZ12/RbAp48/AEBP2 activity using purified enzyme complex or EZH2/EED/SUZ12/RbAp48/AEBP2 extracts. The EZH2/EED/SUZ12/RbAp48/AEBP2 Direct Activity Assay Kit comes in a convenient format, with a 96-well plate precoated with...
| Schlagworte: | KMT6, ENX-1, Enhancer of zeste homolog 2, Lysine N-methyltransferase 6, Histone-lysine N-methyltransferase EZH2, |
| Anwendung: | Enzyme kinetics, HTS |
2.239,00 €