Zu "K11426" wurden 86 Artikel gefunden!
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BAY-598 R-isomer
Artikelnummer: TGM-T26744-1mg
Description: BAY-598 R-isomer is the R-isomer of BAY589, which is used as a reference compound. It is is an inhibitor of lysine N-methyltransferase (SMYD2) and is selective for SMYD2 over protease-activated receptor 1 (PAR1). Target: Others. Smiles:...
| Schlagworte: | BAY598 R-isomer, BAY 598 R-isomer |
| Anwendung: | SMYD2 inhibitor |
| CAS | 1906920-28-2 |
| MW: | 525.34 D |
ab 217,00 €
BAY-6035
Artikelnummer: TGM-T36631-100mg
Description: BAY-6035 is an inhibitor of SET and MYND domain-containing protein 3 (SMYD3). BAY-6035 has more than 100-fold selectivity over other histone methyltransferases. Target: Histone Methyltransferase, MEK. Smiles: C[C@H]1CC(=O)Nc2cc(ccc2N1C(=O)N1CC2CC2C1)C(=O)NCCC1CC1. References: Edoardo F, et, al....
| Anwendung: | SMYD3 inhibitor |
| CAS | 2247890-13-5 |
| MW: | 396.48 D |
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BCI-121
Artikelnummer: TGM-T5322-100mg
Description: BCI-121 is a substrate-competitive SMYD3 inhibitor that inhibits the proliferation of the cancer cell. Target: Histone Methyltransferase. Smiles: NC(=O)C1CCN(CC(=O)Nc2ccc(Br)cc2)CC1. References: Peserico A, et al. A SMYD3 Small-Molecule Inhibitor Impairing Cancer Cell Growth. J Cell Physiol. 2015...
| Anwendung: | SMYD3 inhibitor |
| CAS | 432529-82-3 |
| MW: | 340.22 D |
ab 31,00 €
LLY-507
Artikelnummer: TGM-T6879-100mg
Description: LLY-507 is an effective, cell-active, and specific inhibitor of protein-lysine Methyltransferase SMYD2. Target: Histone Methyltransferase. Smiles: Cc1cn(CCN2CCN(CC2)c2ccccc2-c2cc(cc(c2)C(=O)NCCCN2CCCC2)C#N)c2ccccc12. References: Nguyen H, et al. J Biol Chem. 2015, 290(22):13641-53.
| Schlagworte: | LLY507, LLY 507 |
| Anwendung: | SMYD2 inhibitor |
| CAS | 1793053-37-8 |
| MW: | 574.76 D |
ab 38,00 €
BAY-598
Artikelnummer: TGM-T7403-100mg
Description: BAY-598 is a selective inhibitor of SMYD2 with IC50 values of 27 nM. Target: Histone Methyltransferase. Smiles: CCN([C@H]1CN(N=C1c1ccc(Cl)c(Cl)c1)C(\NC#N)=N\c1cccc(OC(F)F)c1)C(=O)CO. References: Reynoird N , Mazur P K , Stellfeld T , et al. Coordination of stress signals by the lysine methyltransferase...
| Anwendung: | SMYD2 inhibitor |
| CAS | 1906919-67-2 |
| MW: | 525.34 D |
ab 43,00 €
SMYD2 Protein, Human, Recombinant (His)
Artikelnummer: TGM-TMPY-01204-50ug
Description: SET and MYND domain-containing protein 2, also known as HSKM-B, SMYD2, and KMT3C, is a member of the SMYD protein family. It contains one MYND-type zinc finger and one SET domain. Not much is known about SMYD2. However, the interest in better understanding the roles of SMYD2 has grown because of reports...
| Schlagworte: | KMT3C, HSKM-B, SET and MYND domain containing 2, ZMYND14 |
| MW: | 52 kD |
599,00 €
SMYD3 Protein, Human, Recombinant (GST)
Artikelnummer: TGM-TMPY-01268-50ug
Description: SET and MYND domain-containing protein 3, also known as Zinc finger MYND domain-containing protein 1, SMYD3, and ZMYND, is a member of the histone-lysine methyltransferase family. SMYD3 contains one MYND-type zinc finger and one SET domain. SMYD3 is a histone H3 lysine-4-specific methyltransferase. It...
| Schlagworte: | bA74P14.1, ZNFN3A1, SET and MYND domain containing 3, ZMYND1, KMT3E |
| MW: | 656 kD |
599,00 €
SMYD3 Protein, Human, Recombinant (His & Myc)
Artikelnummer: TGM-TMPH-01484-100ug
Description: SMYD3 Protein, Human, Recombinant (His & Myc) is expressed in E. coli.
| Schlagworte: | Zinc finger MYND domain-containing protein 1, SMYD3, SET and MYND domain-containing protein 3, Histone-lysine... |
| MW: | 56.5 kD |
ab 281,00 €
AZ505
Artikelnummer: TGM-TQ0100-100mg
Description: AZ505 is an effective and specific SMYD2 inhibitor (IC50: 0.12 µM). Target: Histone Methyltransferase. Smiles: Oc1ccc(CCNCCN(C2CCCCC2)C(=O)CCNCCc2ccc(Cl)c(Cl)c2)c2OCC(=O)Nc12. References: Komatsu S, et al. Overexpression of SMYD2 contributes to malignant outcome in gastric cancer. Br J Cancer. 2015 Jan...
| Anwendung: | SMYD2 inhibitor |
| CAS | 1035227-43-0 |
| MW: | 577.54 D |
ab 58,00 €
SET and MYND domain-containing protein 3 (SMYD3), human,...
Artikelnummer: CSB-YP884482HU.1
Organism: Homo sapiens (Human). Source: Yeast. Expression Region: 1-428aa. Protein Length: Full Length. Tag Info: N-terminal Flag-tagged and C-terminal 6xHis-Myc-tagged. Target Protein Sequence: MEPLKVEKFA TAKRGNGLRA VTPLRPGELL FRSDPLAYTV CKGSRGVVCD RCLLGKEKLM RCSQCRVAKY CSAKCQKKAW PDHKRECKCL KSCKPRYPPD SVRLLGRVVF...
| Schlagworte: | SMYD3, ZMYND1, Histone-lysine N-methyltransferase SMYD3, SET and MYND domain-containing protein 3, Zinc finger MYND... |
| Anwendung: | Activity not tested |
| Exprimiert in: | Yeast |
| Ursprungsart: | human |
| MW: | 53.5 kD |
ab 347,00 €
Histone-lysine N-methyltransferase SMYD3 (SMYD3), human,...
Artikelnummer: CSB-EP884482HU.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 1-428aa. Protein Length: Full Length. Tag Info: N-terminal 10xHis-tagged and C-terminal Myc-tagged. Target Protein Sequence: MEPLKVEKFA TAKRGNGLRA VTPLRPGELL FRSDPLAYTV CKGSRGVVCD RCLLGKEKLM RCSQCRVAKY CSAKCQKKAW PDHKRECKCL KSCKPRYPPD SVRLLGRVVF...
| Schlagworte: | SMYD3, ZMYND1, Histone-lysine N-methyltransferase SMYD3, SET and MYND domain-containing protein 3, Zinc finger MYND... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 56.5 kD |
ab 292,00 €
Anti-SMYD2
Artikelnummer: CSB-PA004122.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-SMYD2, Anti-KMT3C, Anti-HSKM-B, Anti-Lysine N-methyltransferase 3C, Anti-Histone methyltransferase SMYD2,... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 126,00 €